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The map label for this gene is baeR

Identifier: 218695701

GI number: 218695701

Start: 2394306

End: 2395028

Strand: Direct

Name: baeR

Synonym: EC55989_2335

Alternate gene names: 218695701

Gene position: 2394306-2395028 (Clockwise)

Preceding gene: 218695700

Following gene: 218695702

Centisome position: 46.45

GC content: 53.8

Gene sequence:

>723_bases
ATGACCGAGTTACCAATCGACGAAAACACACCGCGTATTTTGATCGTGGAAGATGAACCGAAGCTGGGACAGTTGCTCAT
TGATTATCTGCGTGCTGCGAGCTATGCGCCGACGCTTATCAGCCACGGCGATCAGGTACTGCCGTATGTGCGCCAGACAC
CACCGGATCTGATCCTGTTAGATCTGATGCTCCCTGGCACCGATGGCCTGACGCTGTGCCGGGAAATTCGTCGTTTTTCT
GACATTCCGATCGTGATGGTGACGGCAAAAATCGAAGAGATCGATCGCCTGCTGGGGCTGGAGATTGGCGCAGATGATTA
TATCTGTAAGCCGTACAGCCCACGGGAAGTGGTAGCGCGCGTCAAAACCATTTTGCGCCGTTGCAAACCGCAGCGCGAGT
TGCAGCAACAGGATGCTGAAAGCCCGTTGATTATCGACGAAGGTCGTTTTCAGGCTTCATGGCGCGGTAAAATGCTTGAC
CTGACGCCTGCGGAATTTCGTCTGCTGAAAACGCTCTCTCATGAACCAGGAAAAGTGTTCTCCCGCGAGCATTTGCTCAA
TCATCTTTATGACGACTACCGCGTAGTAACCGACCGCACCATCGACAGCCACATTAAAAACCTGCGCCGCAAGCTGGAAT
CTCTCGACGCCGAACAGTCATTTATCCGCGCCGTTTACGGCGTTGGTTACCGCTGGGAAGCCGACGCCTGCCGCATCGTT
TAG

Upstream 100 bases:

>100_bases
TTGAAGCACATAATGGCCGCATTATTGCTGCCCATTCGCCTTTTGGCGGGGTAAGCATTACAGTAGAGTTACCGCTGGAA
CGGGATTTACAGAGAGAAGT

Downstream 100 bases:

>100_bases
TTTTAGCGACATGACTTTGTTAGCCGGAGATGGCGTTCAGACCAGATCCGGCAACATTATCCCACGCATGGTCAGCAAAC
TGACATTATCTCTCCGCCCT

Product: DNA-binding transcriptional regulator BaeR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFS
DIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
LTPAEFRLLKTLSHEPGKVFSREHLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV

Sequences:

>Translated_240_residues
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFS
DIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
LTPAEFRLLKTLSHEPGKVFSREHLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV
>Mature_239_residues
TELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSD
IPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLDL
TPAEFRLLKTLSHEPGKVFSREHLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV

Specific function: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=99.5833333333333, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=41.7777777777778, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=39.7321428571429, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=37.4468085106383, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=37.7777777777778, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=35.5855855855856, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.1931330472103, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=31.7596566523605, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.0807174887892, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.2222222222222, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=31.8181818181818, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=33.1877729257642, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=31.8385650224215, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=30.0448430493274, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27665; Mature: 27534

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILL
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHCCCCCEEEE
DLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCEECCCCCEECCCCHHHHHHH
VKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLDLTPAEFRLLKTLSHEPGKVF
HHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCHHHHHHHHHHCCCCCHHH
SREHLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV
HHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECCCCCCCC
>Mature Secondary Structure 
TELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILL
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHCCCCCEEEE
DLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCEECCCCCEECCCCHHHHHHH
VKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLDLTPAEFRLLKTLSHEPGKVF
HHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCHHHHHHHHHHCCCCCHHH
SREHLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV
HHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]