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The map label for this gene is yliE

Identifier: 218694307

GI number: 218694307

Start: 934354

End: 936702

Strand: Direct

Name: yliE

Synonym: EC55989_0878

Alternate gene names: 218694307

Gene position: 934354-936702 (Clockwise)

Preceding gene: 218694306

Following gene: 218694308

Centisome position: 18.13

GC content: 41.72

Gene sequence:

>2349_bases
ATGCTGAGTTTATACGAAAAGATAAAGATAAGGCTGATAATTTTATTTTTATTGGCAGCACTGTCATTTATTGGTCTTTT
TTTCATCATTAACTATCAACTGGTATCGGAACGCGCGGTAAAACGTGCCGATAGCCGCTTTGAACTTATTCAGAAAAACG
TTGGCTATTTCTTTAAAGATATTGAACGTTCGGCCCTGACATTAAAGGACTCACTGTATTTATTAAAAAATACAGAGGAG
ATTCAACGCGCCGTGATTCTGAAAATGGAAATGATGCCATTTTTAGACTCGGTGGGACTGGTACTTGATGATAATAAATA
TTATCTCTTTTCACGGAGGGCGAATGATAAAATCGTTGTTTATCATCAGGAACAAGTAAATGGACCGCTTGTCGACGAGT
CAGGGCGGGTTATTTTTGCCGATTTTAACCCATCGAAACGACCGTGGTCGGTGGCTTCAGATGACTCTAACAACAGCTGG
AATCCGGCATACAATTGCTTTGATCGTCCGGGTAAAAAATGTATCTCTTTTACGCTACGTATCAACGGCAAAGATCACGA
TTTGTTAGCGGTAGATAAAATTCATGTCGATTTAAACTGGCGGTATCTGAACGAGTATCTTGATCAAATCAGCGCTAATG
ATGAAGTTCTATTTTTGAAACAAGGTCATGAGATCATTGCCAAGAATCAACTCGCTCGTGAAAAACTGATTATTTATAAT
AGCGAAGGTAATTATAATATTATTGATTCTGTCGATACGGAGTATATTGCAAAGACATCAGCAGTGCCAAATAATGCATT
GTTCGAAATCTATTTTTATTATCCTGGCGGTAATTTATTGAACGCATCAGATAAACTTTTTTATCTACCGTTTGCGTTCA
TTATTATCGTGTTGCTGGTGGTATATTTCATGACCACTCGTGTGTTCCGTCGGCAATTTTCTGAAATGACCGAGCTGGTT
AATACGCTGGCGTTTTTGCCCGACTCAACGGATCAGATCGAGGCTCTGAAAATTCGCGAAGGCGATGCGAAAGAGATTAT
CAGCATCAAAAATTCGATCGCGGAAATGAAAGATGCCGAAATTGAACGGTCAAATAAATTGCTCTCACTGATCTCTTACG
ATCAGGAAAGCGGTTTTATTAAAAATATGGCGATTATTGAGTCCAACAATAATCAGTATCTGGCTGTGGGGATCATCAAA
CTGTGTGGTCTGGAAGCCGTGGAAGCGGTGTTTGGTGTTGATGAACGCAATAAAATCGTCAGGAAATTGTGTCAGCGAAT
TGCCGAGAAATATGCGCAATGCTGCGATATCGTGACATTCAATGCCGATCTCTATTTACTTCTGTGTCGGGAAAATGTAC
AGACATTTACCCGTAAAATAGCGATGGTAAACGATTTTGACAGCAGCTTTGGCTACCGCAATCTGCGCATCCATAAGTCT
GCCATTTGTGAACCTTTGCAGGGGGAAAACGCCTGGAGTTACGCAGAAAAACTGAAACTGGCGATTTCCAGTATCCGTGA
CCATATGTTCTCCGAGTTTATTTTCTGTGATGACGCGAAACTCAATGAAATAGAAGAGAATATCTGGATTGCGCGTAATA
TTCGCCATGCAATGGAAATTGGCGAACTATTCCTCGTCTATCAACCGATCGTTGATATTAACACCCGCGCCATTCTGGGC
GCGGAGGCGTTGTGCCGTTGGGTTTCTGCGGAGCGGGGGATCATTTCACCGCTGAAGTTCATTACCATTGCTGAAGATAT
CGGGTTTATCAATGAGCTGGGTTATCAGATTATTAAAACGGCAATGGGTGAATTCAGACATTTTAGTCAGCGTGCGTCGC
TGAAGGATGATTTCTTACTGCATATTAATGTTTCGCCCTGGCAGTTAAACGAACCGCACTTTCATGAGCGTTTTACCACC
ATCATGAAAGAAAATGGCCTGAAGGCGAACAGCCTCTGTGTTGAGATCACTGAAACCGTGATCGAGCGAATTAATGAACA
TTTTTATCTCAATATTGAACAACTGCGTAAACAAGGGGTACGGATATCGATTGATGACTTTGGCACCGGTTTGTCAAACC
TGAAACGTTTTTATGAAATTAATCCAGACAGCATAAAGGTGGACTCGCAATTTACCGGCGATATTTTCGGTACTGCGGGA
AAAATTGTGCGCATTATTTTCGATCTGGCACGCTATAACCGGATCCCGGTGATTGCGGAAGGCGTAGAGAGCGAAGACGT
TGCGCGCGAATTAATTAAATTAGGATGTGTTCAGGCTCAGGGGTATCTGTACCAGAAACCCATGCCATTCTCCGCCTGGG
ATAAAAGTGGAAAATTAGTAAAAGAGTAG

Upstream 100 bases:

>100_bases
TGATTTTGTAGAATCGGGTAATTTGGTTAAAAAGCCGCAGCAAGGGACTATTTTTGCAGCGGCACAGCGTTCAGATAGTT
ATTTTGTTAAATGTATTAAC

Downstream 100 bases:

>100_bases
TTTACGTATGTCCAGAATCAATAAGTTCGTACTTACAGTCAGTCTGCTGATTTTTATCATGATTTCAGCAGTTGCCTGCG
GGATCTACACTCAAATGGTA

Product: conserved hypothetical protein; putative inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 782; Mature: 782

Protein sequence:

>782_residues
MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRADSRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEE
IQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGRVIFADFNPSKRPWSVASDDSNNSW
NPAYNCFDRPGKKCISFTLRINGKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLFLKQGHEIIAKNQLAREKLIIYN
SEGNYNIIDSVDTEYIAKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLVVYFMTTRVFRRQFSEMTELV
NTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAEIERSNKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIK
LCGLEAVEAVFGVDERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIAMVNDFDSSFGYRNLRIHKS
AICEPLQGENAWSYAEKLKLAISSIRDHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGELFLVYQPIVDINTRAILG
AEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKTAMGEFRHFSQRASLKDDFLLHINVSPWQLNEPHFHERFTT
IMKENGLKANSLCVEITETVIERINEHFYLNIEQLRKQGVRISIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFGTAG
KIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLVKE

Sequences:

>Translated_782_residues
MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRADSRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEE
IQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGRVIFADFNPSKRPWSVASDDSNNSW
NPAYNCFDRPGKKCISFTLRINGKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLFLKQGHEIIAKNQLAREKLIIYN
SEGNYNIIDSVDTEYIAKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLVVYFMTTRVFRRQFSEMTELV
NTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAEIERSNKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIK
LCGLEAVEAVFGVDERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIAMVNDFDSSFGYRNLRIHKS
AICEPLQGENAWSYAEKLKLAISSIRDHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGELFLVYQPIVDINTRAILG
AEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKTAMGEFRHFSQRASLKDDFLLHINVSPWQLNEPHFHERFTT
IMKENGLKANSLCVEITETVIERINEHFYLNIEQLRKQGVRISIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFGTAG
KIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLVKE
>Mature_782_residues
MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRADSRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEE
IQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGRVIFADFNPSKRPWSVASDDSNNSW
NPAYNCFDRPGKKCISFTLRINGKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLFLKQGHEIIAKNQLAREKLIIYN
SEGNYNIIDSVDTEYIAKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLVVYFMTTRVFRRQFSEMTELV
NTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAEIERSNKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIK
LCGLEAVEAVFGVDERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIAMVNDFDSSFGYRNLRIHKS
AICEPLQGENAWSYAEKLKLAISSIRDHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGELFLVYQPIVDINTRAILG
AEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKTAMGEFRHFSQRASLKDDFLLHINVSPWQLNEPHFHERFTT
IMKENGLKANSLCVEITETVIERINEHFYLNIEQLRKQGVRISIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFGTAG
KIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLVKE

Specific function: Overexpression reduces biofilm formation. Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1787055, Length=782, Percent_Identity=99.616368286445, Blast_Score=1597, Evalue=0.0,
Organism=Escherichia coli, GI1787541, Length=294, Percent_Identity=30.2721088435374, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI87081921, Length=275, Percent_Identity=30.5454545454545, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1790496, Length=254, Percent_Identity=31.1023622047244, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082096, Length=512, Percent_Identity=24.21875, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=29.2887029288703, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI87081980, Length=254, Percent_Identity=30.3149606299213, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788849, Length=250, Percent_Identity=26.8, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786507, Length=249, Percent_Identity=29.3172690763052, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI226510982, Length=267, Percent_Identity=26.2172284644195, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788502, Length=251, Percent_Identity=29.0836653386454, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=26.9709543568465, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 90045; Mature: 90045

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRADSRFELIQKNVGYFFKD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IERSALTLKDSLYLLKNTEEIQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVV
HHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEEEECCCCEEEE
YHQEQVNGPLVDESGRVIFADFNPSKRPWSVASDDSNNSWNPAYNCFDRPGKKCISFTLR
EEHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEE
INGKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLFLKQGHEIIAKNQLAREKLIIYN
ECCCCCCEEEEEEEEEEEEHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCEEEEEE
SEGNYNIIDSVDTEYIAKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLV
CCCCEEEECCCCHHHHHHCCCCCCCCEEEEEEEECCCCEECCCCCEEEHHHHHHHHHHHH
VYFMTTRVFRRQFSEMTELVNTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
IERSNKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIKLCGLEAVEAVFGVDERNKIV
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEHHHHHCHHHHHHHHCCCHHHHHH
RKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIAMVNDFDSSFGYRNLRIHKS
HHHHHHHHHHHHHHHCEEEECCCEEEEEEHHHHHHHHHHHHHEECCCCCCCCCEEEEEHH
AICEPLQGENAWSYAEKLKLAISSIRDHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHH
GELFLVYQPIVDINTRAILGAEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKT
HHHHEEEECCCCCCCHHHHCHHHHHHHHHCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHH
AMGEFRHFSQRASLKDDFLLHINVSPWQLNEPHFHERFTTIMKENGLKANSLCVEITETV
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IERINEHFYLNIEQLRKQGVRISIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFGTAG
HHHCCCCEEEEHHHHHHCCCEEEEHHHCCCHHHHHHHHCCCCCCEEECCCCCCCHHCCHH
KIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLV
HHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCC
KE
CC
>Mature Secondary Structure
MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRADSRFELIQKNVGYFFKD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IERSALTLKDSLYLLKNTEEIQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVV
HHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEEEECCCCEEEE
YHQEQVNGPLVDESGRVIFADFNPSKRPWSVASDDSNNSWNPAYNCFDRPGKKCISFTLR
EEHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEE
INGKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLFLKQGHEIIAKNQLAREKLIIYN
ECCCCCCEEEEEEEEEEEEHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCEEEEEE
SEGNYNIIDSVDTEYIAKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLV
CCCCEEEECCCCHHHHHHCCCCCCCCEEEEEEEECCCCEECCCCCEEEHHHHHHHHHHHH
VYFMTTRVFRRQFSEMTELVNTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHH
IERSNKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIKLCGLEAVEAVFGVDERNKIV
HHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCEEEEEHHHHHCHHHHHHHHCCCHHHHHH
RKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIAMVNDFDSSFGYRNLRIHKS
HHHHHHHHHHHHHHHCEEEECCCEEEEEEHHHHHHHHHHHHHEECCCCCCCCCEEEEEHH
AICEPLQGENAWSYAEKLKLAISSIRDHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHH
GELFLVYQPIVDINTRAILGAEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKT
HHHHEEEECCCCCCCHHHHCHHHHHHHHHCCCCCCCCHHHEEEHHHHHHHHHHHHHHHHH
AMGEFRHFSQRASLKDDFLLHINVSPWQLNEPHFHERFTTIMKENGLKANSLCVEITETV
HHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
IERINEHFYLNIEQLRKQGVRISIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFGTAG
HHHCCCCEEEEHHHHHHCCCEEEEHHHCCCHHHHHHHHCCCCCCEEECCCCCCCHHCCHH
KIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLV
HHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCC
KE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]