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The map label for this gene is crl

Identifier: 218693723

GI number: 218693723

Start: 291961

End: 292362

Strand: Direct

Name: crl

Synonym: EC55989_0264

Alternate gene names: 218693723

Gene position: 291961-292362 (Clockwise)

Preceding gene: 218693722

Following gene: 218693725

Centisome position: 5.66

GC content: 50.75

Gene sequence:

>402_bases
ATGACGTTACCGAGTGGACACCCGAAGAGCAGATTGATCAAAAAATTTACCGCACTAGGCCCGTATATTCGTGAAGGTAA
GTGCGAAGATAATCGATTCTTTTTCGATTGTCTGGCTGTATGCGTCAACGTGAAACCGGCACCGGAAGTGCGTGAGTTCT
GGGGCTGGTGGATGGAGCTGGAAGCGCAGGAATCCCGTTTTACCTACAGCTACCAGTTTGGTCTGTTCGATAAAGCAGGC
GACTGGAAGAGTGTTCCGGTAAAAGATACTGAAGTGGTTGAACGACTGGAACACACCCTGCGTGAGTTTCACGAGAAGCT
GCGTGAACTGCTGACGACGCTGAATCTGAAGCTGGAACCGGCGGATGATTTTCGTGACGAGCCGGTGAAGTTAACGGCGT
GA

Upstream 100 bases:

>100_bases
TCTTCAGGAAATCACCGACTGGATCGAAAAACGTTTGTGTTAAAAATTTGCTAAATTTTACCAATTTGGTAAAACAGTTG
CATCACAACAGGAGATTGCA

Downstream 100 bases:

>100_bases
GTGAAATGTGCCGGATGCATCACATCCGGCAATATCTATTAAAACTGATAGGTCATGCCAACCGCGACAATATCATCATT
ATTAATATTCAATTTGTTAT

Product: DNA-binding transcriptional regulator Crl

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAG
DWKSVPVKDTEVVERLEHTLREFHEKLRELLTTLNLKLEPADDFRDEPVKLTA

Sequences:

>Translated_133_residues
MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAG
DWKSVPVKDTEVVERLEHTLREFHEKLRELLTTLNLKLEPADDFRDEPVKLTA
>Mature_132_residues
TLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGD
WKSVPVKDTEVVERLEHTLREFHEKLRELLTTLNLKLEPADDFRDEPVKLTA

Specific function: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the crl family

Homologues:

Organism=Escherichia coli, GI1786435, Length=133, Percent_Identity=99.2481203007519, Blast_Score=274, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CRL_ECO24 (A7ZHZ9)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001461428.1
- ProteinModelPortal:   A7ZHZ9
- STRING:   A7ZHZ9
- EnsemblBacteria:   EBESCT00000022508
- GeneID:   5586696
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_0272
- eggNOG:   NOG06255
- GeneTree:   EBGT00050000010611
- HOGENOM:   HBG644153
- OMA:   PYIREEQ
- ProtClustDB:   PRK10984
- BioCyc:   ECOL331111:ECE24377A_0272-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_01178
- InterPro:   IPR009986

Pfam domain/function: PF07417 Crl

EC number: NA

Molecular weight: Translated: 15656; Mature: 15525

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMEL
CCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHE
EAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLREFHEKLRELLTTLNLKLEP
ECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ADDFRDEPVKLTA
CCCCCCCCEEECC
>Mature Secondary Structure 
TLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMEL
CCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHE
EAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLREFHEKLRELLTTLNLKLEP
ECCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
ADDFRDEPVKLTA
CCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA