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The map label for this gene is sucC [H]

Identifier: 218692340

GI number: 218692340

Start: 4732445

End: 4733614

Strand: Direct

Name: sucC [H]

Synonym: ECED1_4773

Alternate gene names: 218692340

Gene position: 4732445-4733614 (Clockwise)

Preceding gene: 218692339

Following gene: 218692341

Centisome position: 90.84

GC content: 51.71

Gene sequence:

>1170_bases
ATGAATTTACATGAGTATCAGGCCAAATCGTTACTGGCTGGCATGGGGATGCCGTGTCCAAAAGAGATAGCCATCCAACA
GATTTCGCAACTGGCAGATGCCTGGCAACATATTGCTTGCCCGAGTAAAGGCGCGGTACTTAAAGCGCAGGTACATGCTG
GTGGGCGCGGTAAAGCTGGCGGCGTAAAAGTGCTTAAGCAGCTGCCGGAAGCACAGGCTTTTGTACAGCAAATGTTGGGA
TCGCAACTGGTGACTTATCAGACCGGGCCAGAAGGGCAGTATGTCAGCAGTATTTTGCTGTGCGAAAACATCTATCCGGT
ACGCCAGGAACTCTATTTTGGCATGGTGGTGGATCGTGAAAGCCAGCGGGTCACGTTTATTGTCAGCCCGGAAGGTGGTG
TGGAAATTGAAAAAGTCGCCCATGAGACACCGGAGAAAATCAGCAGTGTCAGCATTGATCCACTGACAGGCGTGCAGCCT
TGCCATATCCGCGAAATGTTTGCTGTTCTGCAACTGGAACACGGGCTATTTGCTGCCTTTAGTCGCCTGGTTAATCAGGC
GTGGAAAGCCTTTAACGAACTGGATTTCGCCCTGCTGGAAATTAACCCTCTGGTGTTGCGGGAAACGGGCGAATTTATGT
GTGCAGACGCGAAAGTATCGCTGGATGATAACGCGCTGTATCGTCACCCGGAACTCCAGGTGCTACGTGATGAAACCCAG
GAAGATCCACGCGAAAGCCAGGCAGCGAAGCTTGATCTTAATTATGTCTCGCTGGACGGAAATATCGGCTGCATGGTCAA
TGGTGCAGGGCTGGCTATGGCAACCATGGACATCATCAAGCTATACGGTGAACAACCCGCAAACTTCCTGGATGTTGGCG
GTGGCGCAACCCAGGAGCGCGTCAGTGAAGCCTTTCGGCTGATTGTTTCCGACAGCAAAGTGAAAGCCATTCTGGTTAAT
ATTTTTGGTGGGATTGTCCGTTGCGACATGATCGCCAGAGCCATTATTCATGCTCTGAATGAGGCCCGTATCACCCTGCC
TGTCGTGGTGCGTCTCTCCGGTAATAACGCTGCCGAAGGGCAGCGGTTACTGGCAGAAAGTGGCCTGACGGTGGAAGCCG
TCAATTCTCTGGATGATGCCGCTAAACGCATCATTGCGTTACTGAATTAA

Upstream 100 bases:

>100_bases
GATCCATGCGCATCCGACCTTAAGCGAAGTCATCCACGAAGCAGCAATGGCCTTGAATAATAAAGCATTACACGGATAAC
ACATACCACTGAGGGAATAT

Downstream 100 bases:

>100_bases
CAGGAGGTTAAGATGAGCGTTTTGATCAACAAACACACGCGGGTACTGGTGCAGGGCATTACCGGCAAAAACGGCACATT
TCATACAGAGCAGGCTATTG

Product: Succinyl-CoA synthetase subunit beta (SCS-beta)

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNLHEYQAKSLLAGMGMPCPKEIAIQQISQLADAWQHIACPSKGAVLKAQVHAGGRGKAGGVKVLKQLPEAQAFVQQMLG
SQLVTYQTGPEGQYVSSILLCENIYPVRQELYFGMVVDRESQRVTFIVSPEGGVEIEKVAHETPEKISSVSIDPLTGVQP
CHIREMFAVLQLEHGLFAAFSRLVNQAWKAFNELDFALLEINPLVLRETGEFMCADAKVSLDDNALYRHPELQVLRDETQ
EDPRESQAAKLDLNYVSLDGNIGCMVNGAGLAMATMDIIKLYGEQPANFLDVGGGATQERVSEAFRLIVSDSKVKAILVN
IFGGIVRCDMIARAIIHALNEARITLPVVVRLSGNNAAEGQRLLAESGLTVEAVNSLDDAAKRIIALLN

Sequences:

>Translated_389_residues
MNLHEYQAKSLLAGMGMPCPKEIAIQQISQLADAWQHIACPSKGAVLKAQVHAGGRGKAGGVKVLKQLPEAQAFVQQMLG
SQLVTYQTGPEGQYVSSILLCENIYPVRQELYFGMVVDRESQRVTFIVSPEGGVEIEKVAHETPEKISSVSIDPLTGVQP
CHIREMFAVLQLEHGLFAAFSRLVNQAWKAFNELDFALLEINPLVLRETGEFMCADAKVSLDDNALYRHPELQVLRDETQ
EDPRESQAAKLDLNYVSLDGNIGCMVNGAGLAMATMDIIKLYGEQPANFLDVGGGATQERVSEAFRLIVSDSKVKAILVN
IFGGIVRCDMIARAIIHALNEARITLPVVVRLSGNNAAEGQRLLAESGLTVEAVNSLDDAAKRIIALLN
>Mature_389_residues
MNLHEYQAKSLLAGMGMPCPKEIAIQQISQLADAWQHIACPSKGAVLKAQVHAGGRGKAGGVKVLKQLPEAQAFVQQMLG
SQLVTYQTGPEGQYVSSILLCENIYPVRQELYFGMVVDRESQRVTFIVSPEGGVEIEKVAHETPEKISSVSIDPLTGVQP
CHIREMFAVLQLEHGLFAAFSRLVNQAWKAFNELDFALLEINPLVLRETGEFMCADAKVSLDDNALYRHPELQVLRDETQ
EDPRESQAAKLDLNYVSLDGNIGCMVNGAGLAMATMDIIKLYGEQPANFLDVGGGATQERVSEAFRLIVSDSKVKAILVN
IFGGIVRCDMIARAIIHALNEARITLPVVVRLSGNNAAEGQRLLAESGLTVEAVNSLDDAAKRIIALLN

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=396, Percent_Identity=45.2020202020202, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=39.119170984456, Blast_Score=274, Evalue=1e-73,
Organism=Homo sapiens, GI294862256, Length=361, Percent_Identity=39.3351800554017, Blast_Score=257, Evalue=1e-68,
Organism=Escherichia coli, GI1786948, Length=386, Percent_Identity=55.9585492227979, Blast_Score=408, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17539378, Length=397, Percent_Identity=38.7909319899244, Blast_Score=294, Evalue=7e-80,
Organism=Caenorhabditis elegans, GI17567829, Length=395, Percent_Identity=41.0126582278481, Blast_Score=286, Evalue=9e-78,
Organism=Saccharomyces cerevisiae, GI6321683, Length=397, Percent_Identity=39.0428211586902, Blast_Score=288, Evalue=1e-78,
Organism=Drosophila melanogaster, GI21356231, Length=403, Percent_Identity=41.6873449131514, Blast_Score=304, Evalue=9e-83,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=43.8144329896907, Blast_Score=297, Evalue=8e-81,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=43.8144329896907, Blast_Score=297, Evalue=8e-81,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=43.9588688946015, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=43.9588688946015, Blast_Score=295, Evalue=4e-80,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42348; Mature: 42348

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKSLLAGMGMPCPKEIAIQQISQLADAWQHIACPSKGAVLKAQVHAGGRGKAG
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCH
GVKVLKQLPEAQAFVQQMLGSQLVTYQTGPEGQYVSSILLCENIYPVRQELYFGMVVDRE
HHHHHHHCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHEEEECC
SQRVTFIVSPEGGVEIEKVAHETPEKISSVSIDPLTGVQPCHIREMFAVLQLEHGLFAAF
CCEEEEEECCCCCCCHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SRLVNQAWKAFNELDFALLEINPLVLRETGEFMCADAKVSLDDNALYRHPELQVLRDETQ
HHHHHHHHHHHHHCCEEEEECCCEEEECCCCEEEECCEEECCCCCEEECCCHHHHHHHHC
EDPRESQAAKLDLNYVSLDGNIGCMVNGAGLAMATMDIIKLYGEQPANFLDVGGGATQER
CCCCHHCCEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHH
VSEAFRLIVSDSKVKAILVNIFGGIVRCDMIARAIIHALNEARITLPVVVRLSGNNAAEG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHH
QRLLAESGLTVEAVNSLDDAAKRIIALLN
HHHHHHCCCEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLHEYQAKSLLAGMGMPCPKEIAIQQISQLADAWQHIACPSKGAVLKAQVHAGGRGKAG
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCH
GVKVLKQLPEAQAFVQQMLGSQLVTYQTGPEGQYVSSILLCENIYPVRQELYFGMVVDRE
HHHHHHHCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHEEEECC
SQRVTFIVSPEGGVEIEKVAHETPEKISSVSIDPLTGVQPCHIREMFAVLQLEHGLFAAF
CCEEEEEECCCCCCCHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SRLVNQAWKAFNELDFALLEINPLVLRETGEFMCADAKVSLDDNALYRHPELQVLRDETQ
HHHHHHHHHHHHHCCEEEEECCCEEEECCCCEEEECCEEECCCCCEEECCCHHHHHHHHC
EDPRESQAAKLDLNYVSLDGNIGCMVNGAGLAMATMDIIKLYGEQPANFLDVGGGATQER
CCCCHHCCEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCCHHH
VSEAFRLIVSDSKVKAILVNIFGGIVRCDMIARAIIHALNEARITLPVVVRLSGNNAAEG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHH
QRLLAESGLTVEAVNSLDDAAKRIIALLN
HHHHHHCCCEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA