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The map label for this gene is tatA

Identifier: 218692130

GI number: 218692130

Start: 4478919

End: 4479188

Strand: Direct

Name: tatA

Synonym: ECED1_4540

Alternate gene names: 218692130

Gene position: 4478919-4479188 (Clockwise)

Preceding gene: 218692129

Following gene: 218692131

Centisome position: 85.98

GC content: 45.93

Gene sequence:

>270_bases
ATGGGTGGTATCAGTATTTGGCAGTTATTGATTATTGCCGTCATCGTTGTACTGCTTTTTGGCACCAAAAAGCTCGGCTC
CATCGGTTCCGATCTTGGTGCGTCGATCAAAGGCTTTAAAAAAGCAATGAGCGATGATGAACCAAAGCAGGATAAAACCA
GCCAGGATGCTGATTTTACTGCGAAAACTATCGCCGATAAGCAGGCGGATACGAATCAGGAACAGGCTAAAACAGAAGAC
GCGAAGCGCCACGATAAAGAGCAGGTGTAA

Upstream 100 bases:

>100_bases
CGGTTGGCGCAAAACACGCTGATTTTTTCATCGCTCAAGGCGGGCCGTGTAACGTATAATGCGGCTTTGTTTAATCATCA
TCTACCACAGAGGAACATGT

Downstream 100 bases:

>100_bases
TCTGTGTTTGATATCGGTTTTAGCGAACTGCTATTGGTGTTCATCATCGGCCTCGTCGTTCTGGGGCCGCAACGACTGCC
TGTGGCGGTAAAAACGGTAG

Product: twin arginine translocase protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 89; Mature: 88

Protein sequence:

>89_residues
MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTED
AKRHDKEQV

Sequences:

>Translated_89_residues
MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTED
AKRHDKEQV
>Mature_88_residues
GGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTEDA
KRHDKEQV

Specific function: Required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif S/T-R-R-X-F-L-K. This sec-independent pathway is termed TAT for twin-arginine translocation system. This system mainly transports protei

COG id: COG1826

COG function: function code U; Sec-independent protein secretion pathway components

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatA/E family

Homologues:

Organism=Escherichia coli, GI87082337, Length=89, Percent_Identity=100, Blast_Score=176, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TATA_ECO57 (P69430)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   F91224
- RefSeq:   NP_290468.1
- RefSeq:   NP_312793.1
- ProteinModelPortal:   P69430
- EnsemblBacteria:   EBESCT00000026088
- EnsemblBacteria:   EBESCT00000058829
- GeneID:   915138
- GeneID:   960322
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5358
- KEGG:   ecs:ECs4766
- GeneTree:   EBGT00050000010284
- HOGENOM:   HBG751935
- OMA:   FETKNIT
- ProtClustDB:   PRK03554
- BioCyc:   ECOL83334:ECS4766-MONOMER
- HAMAP:   MF_00236
- InterPro:   IPR003369
- InterPro:   IPR006312
- TIGRFAMs:   TIGR01411

Pfam domain/function: PF02416 MttA_Hcf106

EC number: NA

Molecular weight: Translated: 9664; Mature: 9533

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x24e90c5c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFT
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
AKTIADKQADTNQEQAKTEDAKRHDKEQV
HHHHHHHCCCCCHHHHHHHHHHHHHCCCH
>Mature Secondary Structure 
GGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFT
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
AKTIADKQADTNQEQAKTEDAKRHDKEQV
HHHHHHHCCCCCHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796