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The map label for this gene is ubiG [H]

Identifier: 218690395

GI number: 218690395

Start: 2629952

End: 2630674

Strand: Direct

Name: ubiG [H]

Synonym: ECED1_2698

Alternate gene names: 218690395

Gene position: 2629952-2630674 (Clockwise)

Preceding gene: 218690388

Following gene: 218690397

Centisome position: 50.48

GC content: 54.08

Gene sequence:

>723_bases
ATGAATGCCGAAAAATCGCCGGTAAACCACAACGTAGACCACAAAGAGATCGCTAAATTTGAAGCCGTCGCCTCCCGCTG
GTGGGATCTTGAAGGTGAGTTCAAACCGCTGCACCGCATTAACCCGCTGCGTCTGGGCTATATTGCCGAGCGTGCTGGCG
GTTTATTTGGCAAAAAGGTGCTCGATGTCGGTTGTGGCGGCGGCATTCTGGCCGAGAGTATGGCGCGGGAGGGCGCGACG
GTGACCGGTCTGGATATGGGCTTTGAGCCATTGCAGGTGGCAAAACTGCACGCACTGGAAAGCGGCATTCAGGTGGATTA
CGTGCAGGAAACCGTGGAAGAGCACGCGGCAAAACATGCCGGACAGTATGACGTGGTGACCTGTATGGAGATGCTGGAGC
ACGTCCCCGATCCTCAGTCAGTGGTCAGAGCCTGTGCGCAACTGGTGAAACCGGGCGGCGATGTCTTTTTCTCGACGCTT
AACCGCAACGGCAAGTCATGGCTGATGGCGGTGGTTGGTGCGGAATATATTTTGCGCATGGTGCCTAAAGGTACACATGA
TGTGAAGAAGTTTATTAAACCGGCAGAATTGCTGGGCTGGGTGGATCAGACCAGTCTTAAAGAACGGCATATGACCGGGC
TGCATTACAACCCTATCACTAATTCCTTTAAGCTCGGCCCCGGCGTGGATGTGAACTATATGCTGCACACGCAGAATAAG
TGA

Upstream 100 bases:

>100_bases
TATAACACAGCCGCGCAGTTTGAGGTAAACCTATACGCTTTATTCACATCCAATGCCTGATATACTCGTTTGTCTTGCCA
ATTACGGAGTAGAAGTGCCA

Downstream 100 bases:

>100_bases
GGTTGTTGTTTGGATTCATCCGGCAACCGAGCCAAGCCTGATGCGGCGCTTGCCGCGTCTTATCAGGCCTACAAATGCTC
CCCGTAGGCCAGATAAGGCG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MNAEKSPVNHNVDHKEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHMTGLHYNPITNSFKLGPGVDVNYMLHTQNK

Sequences:

>Translated_240_residues
MNAEKSPVNHNVDHKEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHMTGLHYNPITNSFKLGPGVDVNYMLHTQNK
>Mature_240_residues
MNAEKSPVNHNVDHKEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHMTGLHYNPITNSFKLGPGVDVNYMLHTQNK

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=236, Percent_Identity=33.8983050847458, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI1788564, Length=240, Percent_Identity=98.75, Blast_Score=496, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI115533050, Length=239, Percent_Identity=31.3807531380753, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6324476, Length=235, Percent_Identity=32.3404255319149, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281365311, Length=229, Percent_Identity=34.061135371179, Blast_Score=141, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24585589, Length=227, Percent_Identity=34.3612334801762, Blast_Score=138, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 26559; Mature: 26559

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAEKSPVNHNVDHKEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCCHHHHHH
LDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHA
HHCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRM
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
VPKGTHDVKKFIKPAELLGWVDQTSLKERHMTGLHYNPITNSFKLGPGVDVNYMLHTQNK
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCEEEEEEECCC
>Mature Secondary Structure
MNAEKSPVNHNVDHKEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHCCHHHHHH
LDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHA
HHCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRM
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
VPKGTHDVKKFIKPAELLGWVDQTSLKERHMTGLHYNPITNSFKLGPGVDVNYMLHTQNK
CCCCHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA