Click here to switch to the map view.

The map label for this gene is rcsB

Identifier: 218690380

GI number: 218690380

Start: 2606676

End: 2607326

Strand: Direct

Name: rcsB

Synonym: ECED1_2683

Alternate gene names: 218690380

Gene position: 2606676-2607326 (Clockwise)

Preceding gene: 218690379

Following gene: 218690382

Centisome position: 50.04

GC content: 47.77

Gene sequence:

>651_bases
ATGAACAATATGAACGTAATTATTGCCGATGACCATCCGATAGTCTTGTTCGGTATTCGCAAATCACTTGAGCAAATTGA
GTGGGTGAATGTTGTCGGCGAATTTGAAGACTCTACAGCACTGATCAACAACCTGCCGAAACTGGATGCGCATGTGTTGA
TTACCGATCTCTCCATGCCTGGCGATAAGTACGGCGATGGCATTACCTTAATCAAGTACATCAAGCGCCATTTCCCAAGC
CTGTCGATCATTGTTCTGACCATGAACAACAACCCGGCGATTCTTAGTGCGGTATTGGATCTGGATATCGAAGGGATCGT
GCTGAAACAAGGTGCACCGACCGATCTGCCGAAAGCTCTCGCCGCGCTGCAGAAAGGGAAAAAATTTACCCCGGAAAGCG
TTTCTCGCCTGTTGGAAAAAATCAGTGCTGGTGGTTACGGTGACAAGCGTCTCTCGCCAAAAGAGAGTGAAGTTCTGCGC
CTGTTTGCGGAAGGCTTCCTGGTGACCGAGATCGCTAAAAAGCTGAACCGCAGTATCAAAACCATCAGTAGCCAGAAGAA
ATCTGCGATGATGAAGCTGGGTGTCGAGAACGATATTGCCCTGCTGAATTATCTCTCTTCAGTGACGTTAAGTCCGGCAG
ATAAAGACTAA

Upstream 100 bases:

>100_bases
GAACATCTGATTCGTGAGAAGGATGTTCCAGGAATAGAAAAATACATCAGCGACATTGACAGTTATGTCAAGAGCTTGCT
GTAGCAAGGTAGCCTATTAC

Downstream 100 bases:

>100_bases
TCACCTGTAGGCCAGATAAGACGCGTCAGTGTCTTATCTGGCATTTGCACGGATTGCCGGATGCGGCATAAACGCCTTAT
CCGTCCTACGATTCCCGCGA

Product: transcriptional regulator RcsB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPS
LSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD

Sequences:

>Translated_216_residues
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPS
LSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD
>Mature_216_residues
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPS
LSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD

Specific function: Also stimulates ftsZ expression. This suggests that rcsB is a regulator implicated in the regulation of more than one cellular function

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788546, Length=216, Percent_Identity=100, Blast_Score=433, Evalue=1e-123,
Organism=Escherichia coli, GI1788521, Length=200, Percent_Identity=31, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=26.5700483091787, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1790102, Length=203, Percent_Identity=29.5566502463054, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=27.1844660194175, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788712, Length=190, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RCSB_ECO57 (P69409)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B91017
- RefSeq:   NP_288797.1
- RefSeq:   NP_311133.1
- ProteinModelPortal:   P69409
- SMR:   P69409
- MINT:   MINT-1221906
- EnsemblBacteria:   EBESCT00000026266
- EnsemblBacteria:   EBESCT00000058685
- GeneID:   916814
- GeneID:   961169
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3476
- KEGG:   ecs:ECs3106
- GeneTree:   EBGT00050000008645
- HOGENOM:   HBG753323
- OMA:   SGYGDKR
- ProtClustDB:   PRK10840
- BioCyc:   ECOL83334:ECS3106-MONOMER
- GO:   GO:0005622
- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00038
- SMART:   SM00421
- SMART:   SM00448

Pfam domain/function: PF00196 GerE; PF00072 Response_reg; SSF46894 Bipartite_resp_reg_C-effector; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 23671; Mature: 23671

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00622 HTH_LUXR_1; PS50043 HTH_LUXR_2; PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP
CCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEEECCCC
GDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKAL
CCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHCCCCEEEEECCCCCCHHHHH
AALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIK
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP
CCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEEECCCC
GDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKAL
CCCCCCCHHHHHHHHHHCCCEEEEEEEECCCCCEEHHHHHCCCCEEEEECCCCCCHHHHH
AALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIK
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796