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The map label for this gene is atoS [H]

Identifier: 218690382

GI number: 218690382

Start: 2610428

End: 2612254

Strand: Direct

Name: atoS [H]

Synonym: ECED1_2685

Alternate gene names: 218690382

Gene position: 2610428-2612254 (Clockwise)

Preceding gene: 218690380

Following gene: 218690383

Centisome position: 50.11

GC content: 48.82

Gene sequence:

>1827_bases
ATGCATTATATGAAGTGGATTTATCCACGCCGCTTACGCAATCAAATGATCCTGATGGCAATCCTGATGGTCATTGTCCC
AACGCTTACTATTGGTTATATCGTAGAAACGGAAGGACGTTCAGCAGTCTTATCTGAAAAAGAGAAAAAACTTTCTGCCG
TGGTCAACCTGCTTAATCAGGCGCTAGGCAATCGCTACGATCTCTACATCGACTTACCGCGTGAGGAGCGTATCCGCGCA
TTAAATGCAGAACTTGCCCCCATTACCGAAAATATCACTCACGCCTTCCCTGGCATCGGCGCTGGTTATTACAACAAAAC
GCTGGATGCGATAATCACCTACGCGCCTTCAGCGCTATATCAGAATAATGTGGGCGTTACCATTGCCGCAGATCACCCTG
GTCGCGAAGTCATGCGTACAAATACCCCTTTGGTTTATTCAGGCAGGCAGGTGCGCGGCGATATTTTGAATTCAATGATT
CCCATTGAGCGTAATGGTGAAATCCTCGGCTATATCTGGGCCAATGAATTAACCGAAGATATTCGCCGCCAGGCCTGGAA
AATGGATGTGAGGATTATCATTGTGCTCACCGCCGGTTTGCTGATAAGCCTGCTGTTGATTGTCCTTTTCTCCCGTCGCC
TGAGCGCCAATATAGATATCATCACCGATGGCCTCTCGACTCTGGCACAAAATATTCCCACTCGATTACCACAATTGCCC
GGTGAAATGGGGCAAATCAGTCAGAGTGTTAACAACCTCGCCCAGGCACTGCGTGAAACGCGAACACTTAACGATCTGAT
TATTGAAAACGCTGCCGATGGCGTCATTGCCATTGACCGCCAGGGTGATGTAACCACCATGAACCCAGCAGCAGAAGTCA
TCACTGGCTATCAACGTCATGAACTGGTAGGGCAGCCTTACTCCATGTTGTTCGACAATACTCAGTTCTACAGTCCAGTA
CTGGATACGCTGGAACATGGCACCGAACATGTAGCACTGGAGATCAGTTTTCCAGGCCGTGACCGCACCATTGAACTCAG
TGTCACGACCAGTCGTATTCATAACACGCACGGTGAAATGATAGGTGCTTTGGTGATTTTCTCTGATTTAACTGCCCGCA
AAGAAACCCAGCGCCGCATGGCGCAAGCAGAACGCCTCGCCACACTGGGTGAGCTGATGGCTGGCGTGGCGCATGAAGTA
CGTAATCCGCTAACAGCTATTCGTGGTTATGTACAGATCTTGCACCAACAAACCCGTGACCCAATACATCAGGAATATCT
GTCCGTAGTACTCAAAGAAATCGATTCAATTAACAAAGTTATTCAGCAATTGCTCGAATTTTCACGTCCACGCCACAGTC
AATGGCAACAAGTCAGCCTCAATGCATTGGTTGAAGAAACTCTGGTACTGGTACAAACCGCCGGCGTACAAGCGCGGGTC
GACTTCATAAGCGAACTGGATAATGAATTAAGCCCGATTAACGCCGATCGTGAACTGCTCAAACAGGTACTACTGAATAT
CCTGATCAATGCCGTCCAGGCTATCAGTGCACGAGGGAAAATTCGCATTCGAACCTGGCAGTATAGCGACTCGCAACAGG
CCATTTCGATAGAGGACAACGGCAGTGGCATTGATCTCTCGCTGCAAAAAAAGATCTTCGATCCCTTTTTCACTACCAAA
GCCCCAGGAACCGGGCTTGGTCTGGCGTTAAGTCAACGCATCATTAATGCCCATCAGGGTGATATTCGCGTCGCCAGTTT
GCCGGGCTACGGCGCAACCTTCACGCTTATTTTACCGATCAACCCGCAGGGAAATCAGACTGTATGA

Upstream 100 bases:

>100_bases
GCAATGTTCTCTCTTCTCTGGAATATGATACACCGCCGAGAAATCATCACCTTAACCTCTGATAATCGTCATATACCGGA
CAAGACTAGTGGATTTCAGC

Downstream 100 bases:

>100_bases
CTGCTATTAATCGCATCCTTATTGTGGATGATGAAGATAATGTTCGCCGTATGCTGAGCACCGCTTTTGCACTACAAGGA
TTCGAAACACATTGTGCGAA

Product: sensory histidine kinase AtoS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 608; Mature: 608

Protein sequence:

>608_residues
MHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVLSEKEKKLSAVVNLLNQALGNRYDLYIDLPREERIRA
LNAELAPITENITHAFPGIGAGYYNKTLDAIITYAPSALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDILNSMI
PIERNGEILGYIWANELTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANIDIITDGLSTLAQNIPTRLPQLP
GEMGQISQSVNNLAQALRETRTLNDLIIENAADGVIAIDRQGDVTTMNPAAEVITGYQRHELVGQPYSMLFDNTQFYSPV
LDTLEHGTEHVALEISFPGRDRTIELSVTTSRIHNTHGEMIGALVIFSDLTARKETQRRMAQAERLATLGELMAGVAHEV
RNPLTAIRGYVQILHQQTRDPIHQEYLSVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEETLVLVQTAGVQARV
DFISELDNELSPINADRELLKQVLLNILINAVQAISARGKIRIRTWQYSDSQQAISIEDNGSGIDLSLQKKIFDPFFTTK
APGTGLGLALSQRIINAHQGDIRVASLPGYGATFTLILPINPQGNQTV

Sequences:

>Translated_608_residues
MHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVLSEKEKKLSAVVNLLNQALGNRYDLYIDLPREERIRA
LNAELAPITENITHAFPGIGAGYYNKTLDAIITYAPSALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDILNSMI
PIERNGEILGYIWANELTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANIDIITDGLSTLAQNIPTRLPQLP
GEMGQISQSVNNLAQALRETRTLNDLIIENAADGVIAIDRQGDVTTMNPAAEVITGYQRHELVGQPYSMLFDNTQFYSPV
LDTLEHGTEHVALEISFPGRDRTIELSVTTSRIHNTHGEMIGALVIFSDLTARKETQRRMAQAERLATLGELMAGVAHEV
RNPLTAIRGYVQILHQQTRDPIHQEYLSVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEETLVLVQTAGVQARV
DFISELDNELSPINADRELLKQVLLNILINAVQAISARGKIRIRTWQYSDSQQAISIEDNGSGIDLSLQKKIFDPFFTTK
APGTGLGLALSQRIINAHQGDIRVASLPGYGATFTLILPINPQGNQTV
>Mature_608_residues
MHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVLSEKEKKLSAVVNLLNQALGNRYDLYIDLPREERIRA
LNAELAPITENITHAFPGIGAGYYNKTLDAIITYAPSALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDILNSMI
PIERNGEILGYIWANELTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANIDIITDGLSTLAQNIPTRLPQLP
GEMGQISQSVNNLAQALRETRTLNDLIIENAADGVIAIDRQGDVTTMNPAAEVITGYQRHELVGQPYSMLFDNTQFYSPV
LDTLEHGTEHVALEISFPGRDRTIELSVTTSRIHNTHGEMIGALVIFSDLTARKETQRRMAQAERLATLGELMAGVAHEV
RNPLTAIRGYVQILHQQTRDPIHQEYLSVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEETLVLVQTAGVQARV
DFISELDNELSPINADRELLKQVLLNILINAVQAISARGKIRIRTWQYSDSQQAISIEDNGSGIDLSLQKKIFDPFFTTK
APGTGLGLALSQRIINAHQGDIRVASLPGYGATFTLILPINPQGNQTV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=608, Percent_Identity=98.6842105263158, Blast_Score=1216, Evalue=0.0,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=41.9753086419753, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1790300, Length=350, Percent_Identity=29.1428571428571, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI145693157, Length=273, Percent_Identity=29.6703296703297, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786600, Length=365, Percent_Identity=23.8356164383562, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786912, Length=308, Percent_Identity=26.9480519480519, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI48994928, Length=421, Percent_Identity=25.41567695962, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788713, Length=367, Percent_Identity=23.9782016348774, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI87081816, Length=267, Percent_Identity=27.3408239700375, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789808, Length=218, Percent_Identity=27.0642201834862, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789149, Length=247, Percent_Identity=25.9109311740891, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788393, Length=264, Percent_Identity=25.3787878787879, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082128, Length=260, Percent_Identity=26.5384615384615, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788279, Length=225, Percent_Identity=25.3333333333333, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67832; Mature: 67832

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVLSEKEKKLSAVVNLLNQ
CCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHH
ALGNRYDLYIDLPREERIRALNAELAPITENITHAFPGIGAGYYNKTLDAIITYAPSALY
HHCCCEEEEEECCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHH
QNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDILNSMIPIERNGEILGYIWANELTED
CCCCCEEEECCCCCHHHHHCCCCEEECCCHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHH
IRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANIDIITDGLSTLAQNIPTRLPQLP
HHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCC
GEMGQISQSVNNLAQALRETRTLNDLIIENAADGVIAIDRQGDVTTMNPAAEVITGYQRH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCHHHHHHCHHHH
ELVGQPYSMLFDNTQFYSPVLDTLEHGTEHVALEISFPGRDRTIELSVTTSRIHNTHGEM
HHCCCCHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEHHHHHHHHHHH
IGALVIFSDLTARKETQRRMAQAERLATLGELMAGVAHEVRNPLTAIRGYVQILHQQTRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PIHQEYLSVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEETLVLVQTAGVQARV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
DFISELDNELSPINADRELLKQVLLNILINAVQAISARGKIRIRTWQYSDSQQAISIEDN
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEECC
GSGIDLSLQKKIFDPFFTTKAPGTGLGLALSQRIINAHQGDIRVASLPGYGATFTLILPI
CCCCEEEHHHHHCCCHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEE
NPQGNQTV
CCCCCCCC
>Mature Secondary Structure
MHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVLSEKEKKLSAVVNLLNQ
CCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHH
ALGNRYDLYIDLPREERIRALNAELAPITENITHAFPGIGAGYYNKTLDAIITYAPSALY
HHCCCEEEEEECCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHH
QNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDILNSMIPIERNGEILGYIWANELTED
CCCCCEEEECCCCCHHHHHCCCCEEECCCHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHH
IRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANIDIITDGLSTLAQNIPTRLPQLP
HHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCC
GEMGQISQSVNNLAQALRETRTLNDLIIENAADGVIAIDRQGDVTTMNPAAEVITGYQRH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCHHHHHHCHHHH
ELVGQPYSMLFDNTQFYSPVLDTLEHGTEHVALEISFPGRDRTIELSVTTSRIHNTHGEM
HHCCCCHHHHHCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEHHHHHHHHHHH
IGALVIFSDLTARKETQRRMAQAERLATLGELMAGVAHEVRNPLTAIRGYVQILHQQTRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PIHQEYLSVVLKEIDSINKVIQQLLEFSRPRHSQWQQVSLNALVEETLVLVQTAGVQARV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
DFISELDNELSPINADRELLKQVLLNILINAVQAISARGKIRIRTWQYSDSQQAISIEDN
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEEECC
GSGIDLSLQKKIFDPFFTTKAPGTGLGLALSQRIINAHQGDIRVASLPGYGATFTLILPI
CCCCEEEHHHHHCCCHHCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEE
NPQGNQTV
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]