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The map label for this gene is ydhM

Identifier: 218689595

GI number: 218689595

Start: 1807990

End: 1808505

Strand: Direct

Name: ydhM

Synonym: ECED1_1849

Alternate gene names: 218689595

Gene position: 1807990-1808505 (Clockwise)

Preceding gene: 218689592

Following gene: 218689596

Centisome position: 34.71

GC content: 52.13

Gene sequence:

>516_bases
ATGGGGCTAAGCGAACTCCTAAAAACCGCTGAAGTGCCGAAAGGGTCCTTCTATCACTACTTTCGTTCTAAAGAAGCGTT
TGGCGTTGCTATGCTTGAGCGCCATTACGCCGCATATCACCAGCGACTGACTGAGTTGCTGCAATCCGGCGAAGGTAACT
ACCGCGACCGCATACTGGCTTATTACCAGCAAACACTGAACCAGTTTTGCCAACATGGAACCATCAGTGGTTGCCTGACA
GTAAAACTCTCTGCCGAAGTGTGCGATCTGTCAGAAGATATGCGCAGCGCAATGGATAAAGGGGCTCGCGGCGTGATCGC
CCTGCTCTCTCAGGCGCTGGAAAATGGCCGTGAGAACCATTGTTTAACCTTTTGTGGCGAACCGCTGCAACAGGCACAAG
TGCTTTACGCACTGTGGCTTGGCGCGAATCTGCAGGCCAAAATTTCGCGCAGTTTCGAGCCACTGGAAAACGCGCTGGCC
CATGTAAAAAACATTATTGCGACGCCTGCCGTTTAG

Upstream 100 bases:

>100_bases
TACTACACTCCAACGCATGAACAAACACACCGAACATGATACTCGCGAACATCTCCTGGCGACGGGCGAGCAACTTTGCC
TGCAACGTGGATTCACCGGG

Downstream 100 bases:

>100_bases
CAGGCATTTTTTATCACCAGACGACCGGGAGCCTTTATGTCATCTGAAAAACTGTATTCCCCACTGAAAGTGGGCGCGAT
CACGGCGGCAAATCGTATTT

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MGLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGTISGCLT
VKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQAQVLYALWLGANLQAKISRSFEPLENALA
HVKNIIATPAV

Sequences:

>Translated_171_residues
MGLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGTISGCLT
VKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQAQVLYALWLGANLQAKISRSFEPLENALA
HVKNIIATPAV
>Mature_170_residues
GLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGTISGCLTV
KLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQAQVLYALWLGANLQAKISRSFEPLENALAH
VKNIIATPAV

Specific function: Represses the transcription of the nemRA operon by binding to the nemR box

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI145693141, Length=171, Percent_Identity=100, Blast_Score=355, Evalue=1e-100,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NEMR_ECOL6 (P67431)

Other databases:

- EMBL:   AE014075
- RefSeq:   NP_753937.1
- ProteinModelPortal:   P67431
- SMR:   P67431
- EnsemblBacteria:   EBESCT00000045186
- GeneID:   1036152
- GenomeReviews:   AE014075_GR
- KEGG:   ecc:c2042
- GeneTree:   EBGT00050000009067
- HOGENOM:   HBG658459
- OMA:   TAGVPKG
- ProtClustDB:   CLSK880155
- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- Gene3D:   G3DSA:1.10.357.10

Pfam domain/function: PF00440 TetR_N; SSF46689 Homeodomain_like; SSF48498 TetR_like_C

EC number: NA

Molecular weight: Translated: 19070; Mature: 18939

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS01081 HTH_TETR_1; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILA
CCHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YYQQTLNQFCQHGTISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENH
HHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
CLTFCGEPLQQAQVLYALWLGANLQAKISRSFEPLENALAHVKNIIATPAV
CHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GLSELLKTAEVPKGSFYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILA
CHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YYQQTLNQFCQHGTISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENH
HHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
CLTFCGEPLQQAQVLYALWLGANLQAKISRSFEPLENALAHVKNIIATPAV
CHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157