The gene/protein map for NC_011745 is currently unavailable.
Definition Escherichia coli ED1a chromosome, complete genome.
Accession NC_011745
Length 5,209,548

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The map label for this gene is int [H]

Identifier: 218688736

GI number: 218688736

Start: 946145

End: 947152

Strand: Direct

Name: int [H]

Synonym: ECED1_0923

Alternate gene names: 218688736

Gene position: 946145-947152 (Clockwise)

Preceding gene: 218688735

Following gene: 218688737

Centisome position: 18.16

GC content: 48.71

Gene sequence:

>1008_bases
TTGGAGGGGCTAATCATGTCGATTAAGCAACTCAAAGACGGGCGTTATAAGGTTGATGTAAGACCGCAAGGGACGGAAGG
AAAGCGGATCCGTAAGATTTTTACCCTGAAGTCAAAGGCACAGGAGTTTGAAAGGTATGTTTTGCAGAATTTCCACGATA
AACCGTGGCAGGCCAAGCCAGCTGATCAGCGTCGGTTATCCGAACTGATAGATGCCTGGTGGGTGCTTGATGGCCGGAAT
CAGCCTTACGGGGATACTTACAGGGTCAGGCTGGAAAAAATAAACCGTGAGATGAGGGACCCCTGCGCCAGTGAGATGAC
GCGAAAGTTTATGCTCGGGTATCGTTCAGACAAATTACAGGCCGGATTAATGCCCTCCAGTGTTAATCGTGATTTGTGCG
CCTTGTCTGCAATGTTTACCTCGCTGATTGATGCGGAGGTTTTCCATAACGAAAACCCGGTGCGTGGAATACGTAAGCTC
AAGGTCAGGAATACAGAAATGGCCTTTCTTTCAGATGATGAGATTGATCGGCTGCTTGAACGACTCGAGGGGGATGCGCG
TCGTGTTGCTGTTCTGTGTCTTTCCACTGGCGCAAGGTGGGGGGAAGCAGCTGGCTTACGTGGTGAGCATATCGTTGGTA
ACCGCGTAATGTTCTTTAACACAAAGAATGGAAAATCCCGCGCGGTTCCTGTTTCTGATACGGTGCTTTCGTTGATAAAA
ACCCGAAAAACCGGGCTATTGTACCAGGCTGATTACATCCGTTTTCGGGATATCCTTCAGGAGGTGAAACCGGATTTACC
CAAAGGTCAGGCGACTCACGTTATGCGTCACACGTTCGCCACGCATTTCATGATGAACGGCGGAAATATCGTTACGTTAC
AGCGAATCCTTGGGCACACCACGATTCAACAAACGATGACGTATGCGCATTTTTCACCGGACTTTTTACAGGATGCGATT
AGCTTTAATCCGCTGGCTGATAGTGTCCATAAACTGTCCATTGACTAG

Upstream 100 bases:

>100_bases
CGGCATTACCCAAAAATCACCCCGATCTCGTCGCAATGCTGGCTAACGCTGTACATCGAGCGGGTTTCATCCCGTAGAGA
GTGTACGGCTGATTCATCCG

Downstream 100 bases:

>100_bases
TTGTAATTTGCGTTAATTTGCTCCCCTTTTTTTGATTTAGTCATTGAAAAATAAGTAAATCATCAAGGGGGGTAAGGTGT
GTTAAATCTCCTGCGGGCGC

Product: Integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MEGLIMSIKQLKDGRYKVDVRPQGTEGKRIRKIFTLKSKAQEFERYVLQNFHDKPWQAKPADQRRLSELIDAWWVLDGRN
QPYGDTYRVRLEKINREMRDPCASEMTRKFMLGYRSDKLQAGLMPSSVNRDLCALSAMFTSLIDAEVFHNENPVRGIRKL
KVRNTEMAFLSDDEIDRLLERLEGDARRVAVLCLSTGARWGEAAGLRGEHIVGNRVMFFNTKNGKSRAVPVSDTVLSLIK
TRKTGLLYQADYIRFRDILQEVKPDLPKGQATHVMRHTFATHFMMNGGNIVTLQRILGHTTIQQTMTYAHFSPDFLQDAI
SFNPLADSVHKLSID

Sequences:

>Translated_335_residues
MEGLIMSIKQLKDGRYKVDVRPQGTEGKRIRKIFTLKSKAQEFERYVLQNFHDKPWQAKPADQRRLSELIDAWWVLDGRN
QPYGDTYRVRLEKINREMRDPCASEMTRKFMLGYRSDKLQAGLMPSSVNRDLCALSAMFTSLIDAEVFHNENPVRGIRKL
KVRNTEMAFLSDDEIDRLLERLEGDARRVAVLCLSTGARWGEAAGLRGEHIVGNRVMFFNTKNGKSRAVPVSDTVLSLIK
TRKTGLLYQADYIRFRDILQEVKPDLPKGQATHVMRHTFATHFMMNGGNIVTLQRILGHTTIQQTMTYAHFSPDFLQDAI
SFNPLADSVHKLSID
>Mature_335_residues
MEGLIMSIKQLKDGRYKVDVRPQGTEGKRIRKIFTLKSKAQEFERYVLQNFHDKPWQAKPADQRRLSELIDAWWVLDGRN
QPYGDTYRVRLEKINREMRDPCASEMTRKFMLGYRSDKLQAGLMPSSVNRDLCALSAMFTSLIDAEVFHNENPVRGIRKL
KVRNTEMAFLSDDEIDRLLERLEGDARRVAVLCLSTGARWGEAAGLRGEHIVGNRVMFFNTKNGKSRAVPVSDTVLSLIK
TRKTGLLYQADYIRFRDILQEVKPDLPKGQATHVMRHTFATHFMMNGGNIVTLQRILGHTTIQQTMTYAHFSPDFLQDAI
SFNPLADSVHKLSID

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 38476; Mature: 38476

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGLIMSIKQLKDGRYKVDVRPQGTEGKRIRKIFTLKSKAQEFERYVLQNFHDKPWQAKP
CCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ADQRRLSELIDAWWVLDGRNQPYGDTYRVRLEKINREMRDPCASEMTRKFMLGYRSDKLQ
HHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHH
AGLMPSSVNRDLCALSAMFTSLIDAEVFHNENPVRGIRKLKVRNTEMAFLSDDEIDRLLE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHH
RLEGDARRVAVLCLSTGARWGEAAGLRGEHIVGNRVMFFNTKNGKSRAVPVSDTVLSLIK
HHCCCHHEEEEEEEECCCCCCCCCCCCCCEEECCEEEEEECCCCCCCCCCHHHHHHHHHH
TRKTGLLYQADYIRFRDILQEVKPDLPKGQATHVMRHTFATHFMMNGGNIVTLQRILGHT
HHHCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEECCCCEEEHHHHHCHH
TIQQTMTYAHFSPDFLQDAISFNPLADSVHKLSID
HHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCC
>Mature Secondary Structure
MEGLIMSIKQLKDGRYKVDVRPQGTEGKRIRKIFTLKSKAQEFERYVLQNFHDKPWQAKP
CCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ADQRRLSELIDAWWVLDGRNQPYGDTYRVRLEKINREMRDPCASEMTRKFMLGYRSDKLQ
HHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCHH
AGLMPSSVNRDLCALSAMFTSLIDAEVFHNENPVRGIRKLKVRNTEMAFLSDDEIDRLLE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHH
RLEGDARRVAVLCLSTGARWGEAAGLRGEHIVGNRVMFFNTKNGKSRAVPVSDTVLSLIK
HHCCCHHEEEEEEEECCCCCCCCCCCCCCEEECCEEEEEECCCCCCCCCCHHHHHHHHHH
TRKTGLLYQADYIRFRDILQEVKPDLPKGQATHVMRHTFATHFMMNGGNIVTLQRILGHT
HHHCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEECCCCEEEHHHHHCHH
TIQQTMTYAHFSPDFLQDAISFNPLADSVHKLSID
HHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA