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The map label for this gene is ldrD [H]

Identifier: 218550815

GI number: 218550815

Start: 3611946

End: 3612188

Strand: Reverse

Name: ldrD [H]

Synonym: EFER_3529

Alternate gene names: 218550815

Gene position: 3612188-3611946 (Counterclockwise)

Preceding gene: 218550817

Following gene: 218550813

Centisome position: 78.72

GC content: 52.67

Gene sequence:

>243_bases
GTGGCATTGGTTGCTGGAGAGAGAAAACCCCCGCATATTGCAGGTATGCACCTGACAACATCACGGGGGCCATTCTTGAA
CCTACACAACTCAAGAGTAGCCGCGAAACGTTGTCATTACAACACTGGCGGCTATATGACGCTCGCAGAGCTGGGCATGG
CCTTCTGGCACGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGATCGTGAACTGGCTGAACAAGCGGAAG
TAA

Upstream 100 bases:

>100_bases
TGAAGAAGTGACGGATTCCGCAGCACAAAAACAGTCGTAGAATCAGCGGCAAGCCGGAAAGATTCCGGTGAGGCGCAATG
TTGCGGGGGCTTAATCCCTG

Downstream 100 bases:

>100_bases
CGTGTCGGACGAGCGTCAGGCTGCCGTAATGGCAATTTGCGCCCGGACCAGGCCGCAGAGGTGAAACTCTGCGGCCTTTT
TCGTAAGAAAAATGCAACGG

Product: toxic polypeptide, small

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 79

Protein sequence:

>80_residues
MALVAGERKPPHIAGMHLTTSRGPFLNLHNSRVAAKRCHYNTGGYMTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Sequences:

>Translated_80_residues
MALVAGERKPPHIAGMHLTTSRGPFLNLHNSRVAAKRCHYNTGGYMTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK
>Mature_79_residues
ALVAGERKPPHIAGMHLTTSRGPFLNLHNSRVAAKRCHYNTGGYMTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Specific function: Toxic peptide whose overexpression causes rapid cell killing and nucleoid condensation of the host cell. Overexpression induces stress-response and a number of membrane protein genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the toxic peptide ldr family [H]

Homologues:

Organism=Escherichia coli, GI48994945, Length=35, Percent_Identity=97.1428571428571, Blast_Score=72, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 8797; Mature: 8665

Theoretical pI: Translated: 10.88; Mature: 10.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVAGERKPPHIAGMHLTTSRGPFLNLHNSRVAAKRCHYNTGGYMTLAELGMAFWHDLA
CCCCCCCCCCCCEECEEEECCCCCEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
APVIAGILASMIVNWLNKRK
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALVAGERKPPHIAGMHLTTSRGPFLNLHNSRVAAKRCHYNTGGYMTLAELGMAFWHDLA
CCCCCCCCCCCEECEEEECCCCCEEECCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
APVIAGILASMIVNWLNKRK
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]