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The map label for this gene is ldrD [H]

Identifier: 218550813

GI number: 218550813

Start: 3611464

End: 3611715

Strand: Reverse

Name: ldrD [H]

Synonym: EFER_3527

Alternate gene names: 218550813

Gene position: 3611715-3611464 (Counterclockwise)

Preceding gene: 218550815

Following gene: 218550809

Centisome position: 78.71

GC content: 50.79

Gene sequence:

>252_bases
TTGATCCCTGGTGGCATTGGTTGCTGGAGAGAGAAAACCCCCGCATGTTGCAGGTATGCACCTGACAATATGAGGGGGCT
AATCTTGAACCCAAACAACTCAAGAATAGCCGCGAAACGTTGTCATTACAACACAGGCGGCTATATGACGCTCGCAGAAC
TGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGATCGTGAACTGGCTGAAC
AAGCGGAAGTAA

Upstream 100 bases:

>100_bases
CAGCACAGAGTGAAGAAGTGACGGATTCCGGAGCACAGAAACAGCCGTAGAATCAGCGGCAAGCCGGAAGAGTTCCGGTG
AGGCGCAATGTTGCGGGGGC

Downstream 100 bases:

>100_bases
CGTGTCATGTGGGCGTCAGCTGCCGTAATGGCAATTTGCGCCCGGACCAGGCCGCAGAGGTGAAACTCTGCGGCCTTTTT
CGTAAGAAAAATGCAACGGT

Product: Small toxic polypeptide ldrD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 83; Mature: 83

Protein sequence:

>83_residues
MIPGGIGCWREKTPACCRYAPDNMRGLILNPNNSRIAAKRCHYNTGGYMTLAELGMAFWHDLAAPVIAGILASMIVNWLN
KRK

Sequences:

>Translated_83_residues
MIPGGIGCWREKTPACCRYAPDNMRGLILNPNNSRIAAKRCHYNTGGYMTLAELGMAFWHDLAAPVIAGILASMIVNWLN
KRK
>Mature_83_residues
MIPGGIGCWREKTPACCRYAPDNMRGLILNPNNSRIAAKRCHYNTGGYMTLAELGMAFWHDLAAPVIAGILASMIVNWLN
KRK

Specific function: Toxic peptide whose overexpression causes rapid cell killing and nucleoid condensation of the host cell. Overexpression induces stress-response and a number of membrane protein genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the toxic peptide ldr family [H]

Homologues:

Organism=Escherichia coli, GI48994945, Length=35, Percent_Identity=97.1428571428571, Blast_Score=72, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 9206; Mature: 9206

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
10.8 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
10.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPGGIGCWREKTPACCRYAPDNMRGLILNPNNSRIAAKRCHYNTGGYMTLAELGMAFWH
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEHHCCCCCCCCCHHHHHHHHHHHH
DLAAPVIAGILASMIVNWLNKRK
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIPGGIGCWREKTPACCRYAPDNMRGLILNPNNSRIAAKRCHYNTGGYMTLAELGMAFWH
CCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEHHCCCCCCCCCHHHHHHHHHHHH
DLAAPVIAGILASMIVNWLNKRK
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]