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The map label for this gene is zntR

Identifier: 218550568

GI number: 218550568

Start: 3354797

End: 3355222

Strand: Reverse

Name: zntR

Synonym: EFER_3276

Alternate gene names: 218550568

Gene position: 3355222-3354797 (Counterclockwise)

Preceding gene: 218550569

Following gene: 218550567

Centisome position: 73.12

GC content: 50.23

Gene sequence:

>426_bases
ATGTATCGCATTGGTGAGCTGGCAAAAATGGCGGAAGTAACACCCGACACGATTCGTTATTACGAAAAGCAGCAGATGAT
GGAGCATGAAGTACGTACCGAAGGTGGGTTTCGCCTGTATACCGAAAGCGATCTCCAGCGATTGAAATTTATCCGCCATG
CCAGACAACTTGGTTTCAGTCTGGAGTCGATCCGCGAGTTGCTGTCGATCCGTATCGATCCTGAGCACCATACCTGTCAG
GAGTCAAAAGGCATTGTGCAGGAAAGATTACAGGAAGTGGAAGCACGGATAGCCGAGTTGCAGAGTATGCAGCGTTCCTT
GCAACGCCTTAACGATGCCTGCTGTGGGACCGCCCATAGCAGTGTTTATTGCTCGATTCTTGAAGCCCTTGAACAAGGGG
CGAGTGGCGTTAAGAGTGGTTGTTGA

Upstream 100 bases:

>100_bases
GAGTTAAAGCTGCGACAAGCAGGATTGAGTACCGATTTTTTACGCGGCGATTATGCTGACAAGTTGTTGAATAAAATCAA
CGATAACTAGTGGAGTATGT

Downstream 100 bases:

>100_bases
TTTTTTGCACTGGCGGGATTACACTCGCGCCGTTAAATAACCAACTGGAGTTTTTATGAGCCGATATCAGCATACTAAAG
GACAGATAAAAGATAATTCG

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESDLQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQ
ESKGIVQERLQEVEARIAELQSMQRSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC

Sequences:

>Translated_141_residues
MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESDLQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQ
ESKGIVQERLQEVEARIAELQSMQRSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC
>Mature_141_residues
MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESDLQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQ
ESKGIVQERLQEVEARIAELQSMQRSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC

Specific function: Zinc-responsive transcriptional regulator of zntA

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1789687, Length=141, Percent_Identity=100, Blast_Score=288, Evalue=1e-79,
Organism=Escherichia coli, GI1786695, Length=138, Percent_Identity=36.9565217391304, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZNTR_ECO57 (P0ACS6)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   E91148
- RefSeq:   NP_289853.2
- RefSeq:   NP_312184.1
- ProteinModelPortal:   P0ACS6
- SMR:   P0ACS6
- EnsemblBacteria:   EBESCT00000027155
- EnsemblBacteria:   EBESCT00000055182
- GeneID:   915990
- GeneID:   958746
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4662
- KEGG:   ecs:ECs4157
- GeneTree:   EBGT00050000009854
- HOGENOM:   HBG710951
- OMA:   GPESAEH
- ProtClustDB:   PRK09514
- BioCyc:   ECOL83334:ECS4157-MONOMER
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788
- PRINTS:   PR00040
- SMART:   SM00422
- TIGRFAMs:   TIGR02043

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; SSF46955 Putativ_DNA_bind

EC number: NA

Molecular weight: Translated: 16180; Mature: 16180

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00552 HTH_MERR_1; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESDLQRLKFIRHARQLGFS
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCC
LESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQSMQRSLQRLNDACCGTAHS
HHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SVYCSILEALEQGASGVKSGC
HHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESDLQRLKFIRHARQLGFS
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCC
LESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQSMQRSLQRLNDACCGTAHS
HHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SVYCSILEALEQGASGVKSGC
HHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796