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The map label for this gene is csrD [H]

Identifier: 218550535

GI number: 218550535

Start: 3316458

End: 3318398

Strand: Reverse

Name: csrD [H]

Synonym: EFER_3230

Alternate gene names: 218550535

Gene position: 3318398-3316458 (Counterclockwise)

Preceding gene: 218550548

Following gene: 218550534

Centisome position: 72.32

GC content: 49.05

Gene sequence:

>1941_bases
ATGAGATTAACGACGAAATTTTCGGCCTTTGTCACGCTGCTCACCGGATTAACGATATTTGTTACGCTGATCGGCTGTAC
GCTGAGCTTTTATAACGCCATTCAGTTTAAGTTTAGTCACCGGGTTCAGGCGGTGGCGACGGCAATTGATACCCATCTGG
TTACCCACGACTTCAAAACGCTTAAGCCACAAATCAATGAACTGATGGTGTCTACTGATATCGTTCGTGTCGATTTTCTT
CAGGGGGAAAAGCTGGTTTATTCCCAGACACGTGGCGGCAGCTATCGCCCTCTTGGTACAAGTAATCAGTTTCGGGATAT
TACTGTTTCATTGGTGAAACATCCGGGCATGTCCTTGCGGCTGGTGTATCAGGATCCGATGGGTAACTATTTCCATTCGC
TGATGACCACGGCACCACTCACCATTGCCATTGGCTTTATCATTATTATGCTTTTTCTGGCCGTACGCTGGTTGCAACGA
CAACTTTCCGGGCAGGAGCTACTGGAGATCCGTTCAACTCGTATTCTGAACGGTGAGCGTGGGGCGAACGTGAGGGGGAC
AATCTACGAGTGGCCACAAAGAACCAGTAGCGCATTAGATATGCTGTTATCAGAAATTCAGAACGCCCGTGAACAGCATA
GCCGACTGGATACACTGATTCGCTCGTATGCTGCACATGACACTAAAACGGGTCTTAATAACCGTTTCTTTTTCGATAAT
CAACTGGCAACGCTTCTGGAAGATCAAGAGAAGGTGGGAACGCATGGCATCGTGATGATGATTCGTCTGCCAGACTTTAC
TTTGCTGAGCGAAACCTGGGGGCATAGCCAGACCGAAGAGCAACTTTTCAGTCTGATCAATCTGTTATCTACCTTTATGA
TGCGCTATCCCGGTGCGTTGCTGGCGCGTTATCACCGCAGTGATTTTACGGTTCTGCTGCCTCATCGCACTCTGAAAGAA
GCGGAAAGCATTGCCGGGCAATTATTGAAGGCAATTGACACGTTGCCGAGCAATAAAATGCTTGATCGTGATGACATGAT
GCACATTGGTATTTGCGGCTGGCGTGGTGGTCAGAGCACTGAGCAAGTGATGGAACATGCGGAGTCTGCAACCCGCAACG
CCGTGTTGCAGGGCGGGAATGGTTGGGCCGTTTATGATGATTCGTTGCCAGAAAAAGGACGCGGAAATGTTCGCTGGCGT
ACGCTTATTGAGCAAATGCTTAGCCGTGGTGGGCCACGGATATATCAAAAACCTGCGGTAACCCGTGAAGGTCATGTCCA
TCATCGTGAGTTGATGTGTCGTATATATGACGGCAACGAAGAAGTCAGCTCCGCTGAATATATGCCTATGGTCCAGCAGT
TTGGCCTGGCAGAAGAGTATGACCGTTTGCAGATTAGCCGTGTGATCCCGTTGCTCAGGTACTGGCCAGAAGAAACGCTG
GCTCTGGAAGTGACAGTAGAGTCATTGATTCGCCCCCGTTTTCAGCGTTGGTTGCGCGATACATTGATGCAATGCGAAAA
ATCGCAGCGTAAACGCATAATTATTGAACTTGCAGAGGCGGATGTAGGTCAACACATCAGCCGTTTGCAATCCGTATTGC
GGTTGGTACACGCGCTGGGTGTTCGGGTGGCGGTAACACAAGCCGGTTTAACACTGGTAAGTACCACCTGGATCAAAGAG
TTGAATGTTGAGTTACTGAAACTTCACCCAAGTCTGGTCAGAAACATCGAGAAGCGCACCGAGAATCAGCTGTTGGTGCA
AAGTTTGGTTGAAGCTTGCACCGGAACAAACACTCAGGTTTATGCCACCGGAGTACGCTCACGTGGTGAGTGGCAGACAC
TGACAGAACGTGGAGTTGCTGGTGGGCAAGGGGAATTTTTTGCGGCCTCTCAGCCACTTGATACTAACGTGAAAAAATAT
TCGCAAAGATACTCGGTTTAA

Upstream 100 bases:

>100_bases
CTCGCTAATTAAATCGCAATGCCGACGAAGCGCAATAAATTGCGAGAAAAATCCTATTTGGTAGTATGCCCGCTTCCCCT
TTATCGGAGTTAAGACAAGG

Downstream 100 bases:

>100_bases
CCTGCCGTTTAATTTGTTTTCACGTAGAATAACGCGCGCTGTGCCTCATGGGAGTGTGCTTGTCTGCTCGCCAGATTGTT
ACAGCGCATTTGCAGGTGAA

Product: regulatory protein CsrD

Products: NA

Alternate protein names: Regulator of CsrB and CsrC decay CsrD [H]

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
MRLTTKFSAFVTLLTGLTIFVTLIGCTLSFYNAIQFKFSHRVQAVATAIDTHLVTHDFKTLKPQINELMVSTDIVRVDFL
QGEKLVYSQTRGGSYRPLGTSNQFRDITVSLVKHPGMSLRLVYQDPMGNYFHSLMTTAPLTIAIGFIIIMLFLAVRWLQR
QLSGQELLEIRSTRILNGERGANVRGTIYEWPQRTSSALDMLLSEIQNAREQHSRLDTLIRSYAAHDTKTGLNNRFFFDN
QLATLLEDQEKVGTHGIVMMIRLPDFTLLSETWGHSQTEEQLFSLINLLSTFMMRYPGALLARYHRSDFTVLLPHRTLKE
AESIAGQLLKAIDTLPSNKMLDRDDMMHIGICGWRGGQSTEQVMEHAESATRNAVLQGGNGWAVYDDSLPEKGRGNVRWR
TLIEQMLSRGGPRIYQKPAVTREGHVHHRELMCRIYDGNEEVSSAEYMPMVQQFGLAEEYDRLQISRVIPLLRYWPEETL
ALEVTVESLIRPRFQRWLRDTLMQCEKSQRKRIIIELAEADVGQHISRLQSVLRLVHALGVRVAVTQAGLTLVSTTWIKE
LNVELLKLHPSLVRNIEKRTENQLLVQSLVEACTGTNTQVYATGVRSRGEWQTLTERGVAGGQGEFFAASQPLDTNVKKY
SQRYSV

Sequences:

>Translated_646_residues
MRLTTKFSAFVTLLTGLTIFVTLIGCTLSFYNAIQFKFSHRVQAVATAIDTHLVTHDFKTLKPQINELMVSTDIVRVDFL
QGEKLVYSQTRGGSYRPLGTSNQFRDITVSLVKHPGMSLRLVYQDPMGNYFHSLMTTAPLTIAIGFIIIMLFLAVRWLQR
QLSGQELLEIRSTRILNGERGANVRGTIYEWPQRTSSALDMLLSEIQNAREQHSRLDTLIRSYAAHDTKTGLNNRFFFDN
QLATLLEDQEKVGTHGIVMMIRLPDFTLLSETWGHSQTEEQLFSLINLLSTFMMRYPGALLARYHRSDFTVLLPHRTLKE
AESIAGQLLKAIDTLPSNKMLDRDDMMHIGICGWRGGQSTEQVMEHAESATRNAVLQGGNGWAVYDDSLPEKGRGNVRWR
TLIEQMLSRGGPRIYQKPAVTREGHVHHRELMCRIYDGNEEVSSAEYMPMVQQFGLAEEYDRLQISRVIPLLRYWPEETL
ALEVTVESLIRPRFQRWLRDTLMQCEKSQRKRIIIELAEADVGQHISRLQSVLRLVHALGVRVAVTQAGLTLVSTTWIKE
LNVELLKLHPSLVRNIEKRTENQLLVQSLVEACTGTNTQVYATGVRSRGEWQTLTERGVAGGQGEFFAASQPLDTNVKKY
SQRYSV
>Mature_646_residues
MRLTTKFSAFVTLLTGLTIFVTLIGCTLSFYNAIQFKFSHRVQAVATAIDTHLVTHDFKTLKPQINELMVSTDIVRVDFL
QGEKLVYSQTRGGSYRPLGTSNQFRDITVSLVKHPGMSLRLVYQDPMGNYFHSLMTTAPLTIAIGFIIIMLFLAVRWLQR
QLSGQELLEIRSTRILNGERGANVRGTIYEWPQRTSSALDMLLSEIQNAREQHSRLDTLIRSYAAHDTKTGLNNRFFFDN
QLATLLEDQEKVGTHGIVMMIRLPDFTLLSETWGHSQTEEQLFSLINLLSTFMMRYPGALLARYHRSDFTVLLPHRTLKE
AESIAGQLLKAIDTLPSNKMLDRDDMMHIGICGWRGGQSTEQVMEHAESATRNAVLQGGNGWAVYDDSLPEKGRGNVRWR
TLIEQMLSRGGPRIYQKPAVTREGHVHHRELMCRIYDGNEEVSSAEYMPMVQQFGLAEEYDRLQISRVIPLLRYWPEETL
ALEVTVESLIRPRFQRWLRDTLMQCEKSQRKRIIIELAEADVGQHISRLQSVLRLVHALGVRVAVTQAGLTLVSTTWIKE
LNVELLKLHPSLVRNIEKRTENQLLVQSLVEACTGTNTQVYATGVRSRGEWQTLTERGVAGGQGEFFAASQPLDTNVKKY
SQRYSV

Specific function: Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility ge

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=646, Percent_Identity=87.1517027863777, Blast_Score=1190, Evalue=0.0,
Organism=Escherichia coli, GI1787410, Length=121, Percent_Identity=25.6198347107438, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1788849, Length=236, Percent_Identity=22.4576271186441, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI87081921, Length=422, Percent_Identity=20.8530805687204, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 73544; Mature: 73544

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTTKFSAFVTLLTGLTIFVTLIGCTLSFYNAIQFKFSHRVQAVATAIDTHLVTHDFKT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKPQINELMVSTDIVRVDFLQGEKLVYSQTRGGSYRPLGTSNQFRDITVSLVKHPGMSLR
HHHHHHHHHHHHCEEEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
LVYQDPMGNYFHSLMTTAPLTIAIGFIIIMLFLAVRWLQRQLSGQELLEIRSTRILNGER
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHEECCCC
GANVRGTIYEWPQRTSSALDMLLSEIQNAREQHSRLDTLIRSYAAHDTKTGLNNRFFFDN
CCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECH
QLATLLEDQEKVGTHGIVMMIRLPDFTLLSETWGHSQTEEQLFSLINLLSTFMMRYPGAL
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHH
LARYHRSDFTVLLPHRTLKEAESIAGQLLKAIDTLPSNKMLDRDDMMHIGICGWRGGQST
HHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCH
EQVMEHAESATRNAVLQGGNGWAVYDDSLPEKGRGNVRWRTLIEQMLSRGGPRIYQKPAV
HHHHHHHHHHHHHHEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCC
TREGHVHHRELMCRIYDGNEEVSSAEYMPMVQQFGLAEEYDRLQISRVIPLLRYWPEETL
CCCCCCHHHHHEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCE
ALEVTVESLIRPRFQRWLRDTLMQCEKSQRKRIIIELAEADVGQHISRLQSVLRLVHALG
EEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHC
VRVAVTQAGLTLVSTTWIKELNVELLKLHPSLVRNIEKRTENQLLVQSLVEACTGTNTQV
CHHEEHHCCHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
YATGVRSRGEWQTLTERGVAGGQGEFFAASQPLDTNVKKYSQRYSV
EEECCCCCCCHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MRLTTKFSAFVTLLTGLTIFVTLIGCTLSFYNAIQFKFSHRVQAVATAIDTHLVTHDFKT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKPQINELMVSTDIVRVDFLQGEKLVYSQTRGGSYRPLGTSNQFRDITVSLVKHPGMSLR
HHHHHHHHHHHHCEEEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEE
LVYQDPMGNYFHSLMTTAPLTIAIGFIIIMLFLAVRWLQRQLSGQELLEIRSTRILNGER
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHEECCCC
GANVRGTIYEWPQRTSSALDMLLSEIQNAREQHSRLDTLIRSYAAHDTKTGLNNRFFFDN
CCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECH
QLATLLEDQEKVGTHGIVMMIRLPDFTLLSETWGHSQTEEQLFSLINLLSTFMMRYPGAL
HHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHH
LARYHRSDFTVLLPHRTLKEAESIAGQLLKAIDTLPSNKMLDRDDMMHIGICGWRGGQST
HHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCH
EQVMEHAESATRNAVLQGGNGWAVYDDSLPEKGRGNVRWRTLIEQMLSRGGPRIYQKPAV
HHHHHHHHHHHHHHEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCCCC
TREGHVHHRELMCRIYDGNEEVSSAEYMPMVQQFGLAEEYDRLQISRVIPLLRYWPEETL
CCCCCCHHHHHEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCE
ALEVTVESLIRPRFQRWLRDTLMQCEKSQRKRIIIELAEADVGQHISRLQSVLRLVHALG
EEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHC
VRVAVTQAGLTLVSTTWIKELNVELLKLHPSLVRNIEKRTENQLLVQSLVEACTGTNTQV
CHHEEHHCCHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
YATGVRSRGEWQTLTERGVAGGQGEFFAASQPLDTNVKKYSQRYSV
EEECCCCCCCHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 3049542 [H]