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The map label for this gene is yvbU [H]

Identifier: 218550124

GI number: 218550124

Start: 2878811

End: 2879731

Strand: Direct

Name: yvbU [H]

Synonym: EFER_2812

Alternate gene names: 218550124

Gene position: 2878811-2879731 (Clockwise)

Preceding gene: 218550117

Following gene: 218550125

Centisome position: 62.74

GC content: 41.59

Gene sequence:

>921_bases
ATGAACCGATTTACCCTTAAACAACTTAAATATTTTGTCACCGTCGTCGAAACAGAAAGTATTGCTGAAGCTTCACGTCA
GTTACACATTGCCCAACCTTCAATTTCTATTGCGATTAAAAATCTCGAAAGCACCTTTGATCAACAACTCTTTATTCGCC
ACCATGCGCAAGGTGTATCGTTAACATCAGGTGGCAGACGTTTCTATGAAAAGGCGAAAGAGCTCTTGCGCTTATCCTGG
GAGTTCGAGCAAAACTCACGTGCCGATAAGGACATGATTTCAGGAACAATTTCAATAGGTTGTTTTGAATCGGTAGCCCC
GTTATATATGCCGAAACTGGTTGCAGGATTCAAAAAACTTTATCCTGAAATTACTCTGCAACTTTATGATGGTGAGCAAC
ATGAATTAATGCACGGTTTACATCGTGGGCGATTTGATCTGGCTTTGTTGTATGATCTGGAGCTGGGTCATACCATCCAT
AAAGAATTACTTAACGCACCGCACCAGCCTTATGCATTATTGCCCGCATCACATCCTTTGGCACGAAAAAAGAGCGTGAC
ACTGCAGGAACTGAGCAAGGAACCCATGATCTTGCTTGATGCCGTGCCGAGCAAAAATTATTTTGTCGCTATTTTCAAAG
AAAAAGGTTATCACCCTCATATTGCTTACAGTTCACCTTCTATTGAAATGGTACGTTGTATGGTTGGACAAGGGTTAGGA
TTTTCAGTATTAGTTACCCGCCCCTGCAGCGATATAACCTATGATGGTGAGCGTCTTGTACAACTCGATATAGAAGATGA
AATGCCTGCATCAACATTAATAATGGCACACCTTGCAAATAATGAACCTACCCGACCGACGCAATTATTTATGGATTACT
GCCGTAACCGTGAATTAATGCCGCCAGGATTACATTATTAA

Upstream 100 bases:

>100_bases
TCGCCATTTATTAAAAAACGGTTAATTTATCTGAAAATGTTTATGGCACGACTCTTGCTACATATATTTTATATCTAACA
GGATAACTGACAGGTAGCCT

Downstream 100 bases:

>100_bases
GCCTCGTAATTTTATATACTCAAGAACGTTTTATAATAATTTACCCACTGCGCGTTGTTATTTAATCTGAGCTTAGTCAA
TTCCGGTAAATACGCCGGTT

Product: regulatory protein, LysR:LysR substrate-binding domain (fragment)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNRFTLKQLKYFVTVVETESIAEASRQLHIAQPSISIAIKNLESTFDQQLFIRHHAQGVSLTSGGRRFYEKAKELLRLSW
EFEQNSRADKDMISGTISIGCFESVAPLYMPKLVAGFKKLYPEITLQLYDGEQHELMHGLHRGRFDLALLYDLELGHTIH
KELLNAPHQPYALLPASHPLARKKSVTLQELSKEPMILLDAVPSKNYFVAIFKEKGYHPHIAYSSPSIEMVRCMVGQGLG
FSVLVTRPCSDITYDGERLVQLDIEDEMPASTLIMAHLANNEPTRPTQLFMDYCRNRELMPPGLHY

Sequences:

>Translated_306_residues
MNRFTLKQLKYFVTVVETESIAEASRQLHIAQPSISIAIKNLESTFDQQLFIRHHAQGVSLTSGGRRFYEKAKELLRLSW
EFEQNSRADKDMISGTISIGCFESVAPLYMPKLVAGFKKLYPEITLQLYDGEQHELMHGLHRGRFDLALLYDLELGHTIH
KELLNAPHQPYALLPASHPLARKKSVTLQELSKEPMILLDAVPSKNYFVAIFKEKGYHPHIAYSSPSIEMVRCMVGQGLG
FSVLVTRPCSDITYDGERLVQLDIEDEMPASTLIMAHLANNEPTRPTQLFMDYCRNRELMPPGLHY
>Mature_306_residues
MNRFTLKQLKYFVTVVETESIAEASRQLHIAQPSISIAIKNLESTFDQQLFIRHHAQGVSLTSGGRRFYEKAKELLRLSW
EFEQNSRADKDMISGTISIGCFESVAPLYMPKLVAGFKKLYPEITLQLYDGEQHELMHGLHRGRFDLALLYDLELGHTIH
KELLNAPHQPYALLPASHPLARKKSVTLQELSKEPMILLDAVPSKNYFVAIFKEKGYHPHIAYSSPSIEMVRCMVGQGLG
FSVLVTRPCSDITYDGERLVQLDIEDEMPASTLIMAHLANNEPTRPTQLFMDYCRNRELMPPGLHY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=245, Percent_Identity=29.3877551020408, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787530, Length=272, Percent_Identity=24.2647058823529, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788887, Length=281, Percent_Identity=26.3345195729537, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790399, Length=243, Percent_Identity=23.0452674897119, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787601, Length=144, Percent_Identity=29.8611111111111, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI145693105, Length=246, Percent_Identity=24.7967479674797, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788297, Length=151, Percent_Identity=31.7880794701987, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI157672245, Length=230, Percent_Identity=28.695652173913, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1789204, Length=266, Percent_Identity=26.6917293233083, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788296, Length=242, Percent_Identity=22.7272727272727, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788748, Length=246, Percent_Identity=25.2032520325203, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787806, Length=153, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI2367136, Length=257, Percent_Identity=24.9027237354086, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790208, Length=248, Percent_Identity=24.5967741935484, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081904, Length=198, Percent_Identity=25.2525252525253, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34874; Mature: 34874

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50931 HTH_LYSR ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFTLKQLKYFVTVVETESIAEASRQLHIAQPSISIAIKNLESTFDQQLFIRHHAQGVS
CCCHHHHHHHHHHHEECHHHHHHHHHEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCE
LTSGGRRFYEKAKELLRLSWEFEQNSRADKDMISGTISIGCFESVAPLYMPKLVAGFKKL
ECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHH
YPEITLQLYDGEQHELMHGLHRGRFDLALLYDLELGHTIHKELLNAPHQPYALLPASHPL
CCEEEEEEECCCHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHCCCCCCEEECCCCCCC
ARKKSVTLQELSKEPMILLDAVPSKNYFVAIFKEKGYHPHIAYSSPSIEMVRCMVGQGLG
HHHHCCHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHCCCCC
FSVLVTRPCSDITYDGERLVQLDIEDEMPASTLIMAHLANNEPTRPTQLFMDYCRNRELM
EEEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHEEECCCCCCCCHHHHHHHHHCCCCCC
PPGLHY
CCCCCC
>Mature Secondary Structure
MNRFTLKQLKYFVTVVETESIAEASRQLHIAQPSISIAIKNLESTFDQQLFIRHHAQGVS
CCCHHHHHHHHHHHEECHHHHHHHHHEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCE
LTSGGRRFYEKAKELLRLSWEFEQNSRADKDMISGTISIGCFESVAPLYMPKLVAGFKKL
ECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHH
YPEITLQLYDGEQHELMHGLHRGRFDLALLYDLELGHTIHKELLNAPHQPYALLPASHPL
CCEEEEEEECCCHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHCCCCCCEEECCCCCCC
ARKKSVTLQELSKEPMILLDAVPSKNYFVAIFKEKGYHPHIAYSSPSIEMVRCMVGQGLG
HHHHCCHHHHHCCCCEEEEECCCCCCEEEEEEECCCCCCEEEECCCCHHHHHHHHCCCCC
FSVLVTRPCSDITYDGERLVQLDIEDEMPASTLIMAHLANNEPTRPTQLFMDYCRNRELM
EEEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHEEECCCCCCCCHHHHHHHHHCCCCCC
PPGLHY
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]