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The map label for this gene is queC [H]

Identifier: 218549888

GI number: 218549888

Start: 2639960

End: 2640655

Strand: Direct

Name: queC [H]

Synonym: EFER_2573

Alternate gene names: 218549888

Gene position: 2639960-2640655 (Clockwise)

Preceding gene: 218549887

Following gene: 218549898

Centisome position: 57.53

GC content: 51.15

Gene sequence:

>696_bases
ATGAAACGTGCTGTCGTTGTGTTCAGTGGAGGCCAGGATTCCACCACCTGTCTGGTGCAGGCATTACAACAATATGATGA
AGTCCATTGCGTGACGTTCGATTACGGTCAGCGACATCGCGCAGAAATCGACGTGGCACGCGAACTGGCGCTGAAACTGG
GGGCACGCGCGCATAAGGTTCTTGATGTAACGCTGCTCAACGAGCTGGCGGTCAGCAGCCTGACACGTGACAGCATTCCA
GTGCCAGATTATGAACCTGAAGCCGATGGCATCCCGAATACGTTTGTCCCAGGCCGTAATATTTTATTCCTGACGCTGGC
GGCAATATATGCGTATCAGGTCAAAGCCGAAGCAGTGATTACCGGCGTCTGCGAAACGGATTTCTCCGGTTACCCGGATT
GCCGCGATGAGTTTGTGAAAGCACTAAACCATGCCGTCAGTTTAGGCATGGCGAAAGATATTCGTTTTGAAACGCCGCTG
ATGTGGATTGATAAAGCGGAAACCTGGGCGCTGGCTGATTATTACGGCAAACTAGATTTAGTCCGTAACGAAACGTTGAC
CTGCTATAACGGCATTAAAGGCGACGGTTGCGGTCATTGTGCGGCGTGTAATTTACGCTCCAACGGTTTGCATCATTATC
TGGCCGATAAACCGACGGTGATGGCAGCGATGAAGCAGAAAACCGGGTTGAAGTAA

Upstream 100 bases:

>100_bases
TTTACCGAAGCCTGGCTTCCCGCGCCGTCGCAATGAATAGCTGGTCCGGGTTAATCGCAGGCGTTACCATAACGCTTTTA
TTGTTCAAGCAGGATTATCT

Downstream 100 bases:

>100_bases
TTATTCCGGGTGTCGCCGGATGCGGCTTGAGCATCCGGCACCACAAAACGTTTACTTAACCATCTGCTCCAGCTTTTCGC
GCAATTCCCCTTCCAGAGCT

Product: queuosine biosynthesis protein QueC

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIP
VPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPL
MWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRSNGLHHYLADKPTVMAAMKQKTGLK

Sequences:

>Translated_231_residues
MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIP
VPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPL
MWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRSNGLHHYLADKPTVMAAMKQKTGLK
>Mature_231_residues
MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIP
VPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPL
MWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRSNGLHHYLADKPTVMAAMKQKTGLK

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=231, Percent_Identity=98.2683982683983, Blast_Score=476, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 25491; Mature: 25491

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKV
CCEEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHH
LDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEE
TGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDL
EEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCEEEEECCCCEEHHHHHCCEEE
VRNETLTCYNGIKGDGCGHCAACNLRSNGLHHYLADKPTVMAAMKQKTGLK
EECCEEEEECCCCCCCCCCEEECCCCCCCCEEHHCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKV
CCEEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHH
LDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVI
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEE
TGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDL
EEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCEEEEECCCCEEHHHHHCCEEE
VRNETLTCYNGIKGDGCGHCAACNLRSNGLHHYLADKPTVMAAMKQKTGLK
EECCEEEEECCCCCCCCCCEEECCCCCCCCEEHHCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA