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The map label for this gene is fepD [H]

Identifier: 218549822

GI number: 218549822

Start: 2566990

End: 2567994

Strand: Direct

Name: fepD [H]

Synonym: EFER_2504

Alternate gene names: 218549822

Gene position: 2566990-2567994 (Clockwise)

Preceding gene: 218549820

Following gene: 218549823

Centisome position: 55.94

GC content: 60.0

Gene sequence:

>1005_bases
ATGTCTGGTTCTGTTGCCGTGACACGCGCCATTGCCGTGCCCGGATTGCTGTTATTACTGATTATCGCGACGGCATTAAG
CCTGCTCATTGGGGCAAAATCACTCCCCGCTTCCGTAGTGCTGGAGGCCCTCTCCGGCACCTGCCAGAGCGCCGACTGCA
CCATCGTGCTCGACGCGCGACTGCCGCGTACCCTTGCCGGTTTACTGGCAGGCGGCGCGCTTGGCCTTGCCGGGGCGTTA
ATGCAAACCCTCACCCGAAACCCACTTGCCGACCCCGGCTTGCTTGGCGTGAACGCCGGGGCCAGCTTTGCCATTGTGCT
GGGCGCGGCGCTGTTTGGTTACTCATCCGCGCAGGAACAACTAGCGATGGCCTTCGCCGGGGCGCTGGTGGCCTCGTTGA
TTGTTGCCTTTACTGGCAGCCAGGGCGGTGGGCAGTTAAGTCCGGTGCGTTTAACTCTGGCGGGCGTGGCGCTGGCGGCA
GTGCTGGAAGGGCTGACCAGCGGCATCGCCCTGCTTAATCCCGACGTCTACGATCAACTGCGTTTCTGGCAAGCCGGTTC
GCTGGATATTCGTAATTTACACACCTTAAAAGTAGTGCTGATCCCGGTGCTGATCGCTGGAGCAACTGCACTATTACTGA
GCCGCGCGCTGAACAGTTTAAGCCTTGGCAGTGACACCGCGACGGCGCTGGGCAGTCGCGTGGCGCGCACACAGTTGATT
GGTCTGCTGACGATTACCGTGCTTTGTGGTAGTGCGACGGCGGTAGTTGGCCCGATTGCTTTTATTGGCCTGATGATGCC
GCACATGGCACGTTGGTTGGTTGGAGCCGATCATCGCTGGTCGCTGCCCGTCACGCTGCTCGCCACACCAGCCCTGCTGC
TGTTTGCCGATATTATCGGGCGTGTGATTGTTCCCGGCGAACTGCGCGTTTCTGTAGTCAGTGCCTTTATTGGCGCACCA
GTGCTGATCTTCCTTGTACGACGTAAAACGCGAGGTGGCGCATGA

Upstream 100 bases:

>100_bases
TGCCATCAAATATTTTAAATACCTATTCTTAGGCTGCACATGCTAACATATCCAAATAAGATCGATAACGATAATTAATT
TCATTATCATGGAAGTTCGT

Downstream 100 bases:

>100_bases
TTTACGTCTCTCGTCGATTAATTATCACCTGTCTGCTGTTGCTAATAGCCTGTGTGATGGCAAGCGTGTGGGGATTACGC
AGCGGTGCCGTCACGCTGGA

Product: iron-enterobactin transporter membrane protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEALSGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGAL
MQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLI
GLLTITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAP
VLIFLVRRKTRGGA

Sequences:

>Translated_334_residues
MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEALSGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGAL
MQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLI
GLLTITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAP
VLIFLVRRKTRGGA
>Mature_333_residues
SGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEALSGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALM
QTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAAV
LEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLIG
LLTITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAPV
LIFLVRRKTRGGA

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=334, Percent_Identity=99.1017964071856, Blast_Score=626, Evalue=0.0,
Organism=Escherichia coli, GI1790741, Length=288, Percent_Identity=38.5416666666667, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1790740, Length=305, Percent_Identity=36.3934426229508, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786804, Length=337, Percent_Identity=35.0148367952522, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786347, Length=277, Percent_Identity=35.3790613718412, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=38.7543252595156, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 33854; Mature: 33723

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEALSGTCQSADCTIVLDAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEECCC
LPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHCCCHHHHH
LAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLTSGIALLNPDVYDQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHH
RFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLI
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GLLTITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
HEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEALSGTCQSADCTIVLDAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEECCC
LPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHCCCHHHHH
LAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLTSGIALLNPDVYDQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHH
RFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLI
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GLLTITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
HEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 1787794; 9278503 [H]