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The map label for this gene is fepG [H]

Identifier: 218549823

GI number: 218549823

Start: 2567991

End: 2568983

Strand: Direct

Name: fepG [H]

Synonym: EFER_2505

Alternate gene names: 218549823

Gene position: 2567991-2568983 (Clockwise)

Preceding gene: 218549822

Following gene: 218549824

Centisome position: 55.96

GC content: 56.8

Gene sequence:

>993_bases
ATGATTTACGTCTCTCGTCGATTAATTATCACCTGTCTGCTGTTGCTAATAGCCTGTGTGATGGCAAGCGTGTGGGGATT
ACGCAGCGGTGCCGTCACGCTGGAAACCTCGCAGGTATTTGCCGCGCTGATGGGTGACGCACCGCGCAGTATGACAATGG
TGGTCACCGAATGGCGTTTACCGCGGGTACTAATGGCGCTGTTGATTGGTGCGGCACTGGGCGTCAGCGGCGCGATTTTT
CAGTCGTTGATGCGTAACCCACTCGGCAGCCCTGACGTAATGGGCTTTAACACCGGAGCGTGGAGCGGCGTGCTGGTGGC
GATGGTGCTGTTTGGTCAGGACCTGACGGCTATCGCGCTGGCAGCAATGGCGGGCGGCATTATCACTTCGCTGCTGGTCT
GGTTGCTTGCCTGGCGTAACGGTATCGACACCTTTCGGTTGATTATTATCGGCATCGGCGTTCGCGCCATGCTGGTGGCC
TTTAATACCTGGCTGTTGCTGAAAGCGTCTTTAGAAACGGCGTTAACAGCGGGTTTGTGGAATGCCGGATCGCTCAATGG
CCTGACGTGGGCAAAAACCTCGCCCTCCGCGCCCATCATTATATTGATGCTAATTGCCGCCGCCTTACTGGTAAGGCGGA
TGCGCTTGCTGGAGATGGGTGATGACACCGCGTGTGCGTTAGGCGTCAGCGTCGAACGTTCGCGTCTATTAATGATGCTG
GTCGCCGTAGTACTTACCGCAGCTGCCACTGCCCTGGCGGGGCCGATTTCCTTTATTGCTTTAGTCGCGCCACACATTGC
CCGCCGCATCAGCGGCACCGCTCGCTGGGGGCTAACCCAGGCGGCGCTGTGCGGTGCGCTGTTACTGCTGGCAGCCGATC
TCTGTGCTCAGCAACTGTTTATGCCGTATCAACTTCCGGTTGGCGTCGTTACCGTCAGCCTCGGCGGTATTTACCTTATC
GTCTTGTTAATTCAGGAGTCTCGCAAAAAATGA

Upstream 100 bases:

>100_bases
GTGTGATTGTTCCCGGCGAACTGCGCGTTTCTGTAGTCAGTGCCTTTATTGGCGCACCAGTGCTGATCTTCCTTGTACGA
CGTAAAACGCGAGGTGGCGC

Downstream 100 bases:

>100_bases
CCGAATCAGTAGCCCGTTTGCGTGGCGAACAGTTAACCCTAGGATATGGCAAATATACCGTTGCGGAAAATCTGACTGTA
GAAATTCCTGATGGTCACTT

Product: iron-enterobactin transporter permease

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MIYVSRRLIITCLLLLIACVMASVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF
QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIITSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI
VLLIQESRKK

Sequences:

>Translated_330_residues
MIYVSRRLIITCLLLLIACVMASVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF
QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIITSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI
VLLIQESRKK
>Mature_330_residues
MIYVSRRLIITCLLLLIACVMASVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF
QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIITSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI
VLLIQESRKK

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=330, Percent_Identity=97.2727272727273, Blast_Score=563, Evalue=1e-162,
Organism=Escherichia coli, GI1790740, Length=288, Percent_Identity=38.1944444444444, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786347, Length=321, Percent_Identity=33.6448598130841, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1786805, Length=309, Percent_Identity=36.8932038834951, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1790741, Length=287, Percent_Identity=33.7979094076655, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788004, Length=294, Percent_Identity=35.3741496598639, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34969; Mature: 34969

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYVSRRLIITCLLLLIACVMASVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRL
CEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEHHHH
PRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIAL
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
AAMAGGIITSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGLW
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHC
MPYQLPVGVVTVSLGGIYLIVLLIQESRKK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIYVSRRLIITCLLLLIACVMASVWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRL
CEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEHHHH
PRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIAL
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
AAMAGGIITSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGLW
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHC
MPYQLPVGVVTVSLGGIYLIVLLIQESRKK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 9278503 [H]