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The map label for this gene is cadC [H]

Identifier: 218549242

GI number: 218549242

Start: 1948017

End: 1949546

Strand: Reverse

Name: cadC [H]

Synonym: EFER_1902

Alternate gene names: 218549242

Gene position: 1949546-1948017 (Counterclockwise)

Preceding gene: 218549243

Following gene: 218549241

Centisome position: 42.49

GC content: 44.51

Gene sequence:

>1530_bases
ATGCAACAACCTGTAGTTCGCGTTGGGGAATGGCTTGTTACTCCGTCGATAAACCAAATAAGTCGCAATGGACGTCAGCT
TACCCTGGAGCCTCGGTTAATCGATCTTTTGGTTTTCTTTGCTCGCCATAGTGGAGAAGTACTTAGCAGAGATGAACTTA
TCGATAATGTCTGGACGAGAAGTGTCGTTACCAATCATGTCGTGACGCAGAGTATTTCAGAGCTGCGTAAATCGCTTAAA
GATGGTGATGAAAATAGCCCTGTCTATATCGCTACTGTACCGAAGCGCGGTTATAAATTAATGGTGCCGGTTATCTGGTG
TACAGAGGAGGAGAGCGAAGAAATAATGTCGGCGTCACCTCCCGCACTACCAGAGACAATACCTGATTCCGCTTCGCCTC
CTGCCATTGCTGAAACCACGACACCGCCACCTCAGACAACCACAGTTAAACGCAAACGATTCACTACCTTTTGGGTATGG
TGTTTCTTTCTTCTTGCCCTGGGAACTTGCGTGGCGCTGGTGGCATTGTCGAGTTTTGAAACACGTCTTCCTGTTAGTAA
ATCGCGTATTTTGCTCAACCCACGCGATATAGATATCCATTTGGTGAATAAGAGTCCATGTAACAACTGGACTTCACAAC
GCTCTTACGCGGTAGGGCTGGGTAGCCTGGTAACAACCTCGCTTAACACCTTCTCCACCTTTATGGTGCATGACAAAACG
AACTACAACATTGATGAACCGAGCAGTTCCGGTAAGACGCTGACCATTGAGTTTGTTAATCAGCGTCATTACCGCGCGCA
ACAATGCTTTATGTCGGTAAAACTGGTGGACAATGCTGATGGCTCAACCATGCTGGATAAACGCTACTTCATTACTAACG
ATAATCAGTTATCGATTCAGAATGATTTACTGGCGAGCTTGTCAAAGGCATTGAATCAACCGTGGCCACAACGAATGCAA
GAGATGTTTCAACAATTTCAACCTCGCCGCGGGGCATTATTAACCAGTTTTTACCAGGCGCATGATTATTTAATGCGGGG
TGATGTCGAATCATTGAGTCGAGCCAGTGAATTGTTAGGTGAGATTCTTGAGGAAGCTCCAGATTTTATCTACGTGCGGG
CAGAGAAAGCATTGGTTGATGTATTACGCCATTCTCAGCATCCTTTAGACGAAAAACAATTAGCGGCTCTGTATGAGGAA
GTTGATAAAGTAGGAGCGATGCCTGGCATGAATGATATGTCTATTTTCTATCAAATTAAAACAGTCAGTGCTTTGGGAAG
CGGGAAAATAGATGAAGCGTATCAGGCGATCAATACCGGCATTGAACTTGAAATGTCGTGGTTAAATTATGTATTGCTGG
GCAAGGTTTATGAAATGAAAGGCATGAACCGTGAAGCCGCTGATGCATATCTGACAGCATTTAATTTACGCCCTGGTGAA
AATACACTTTACTGGATTGAAAACGGCGTATTTCAGACTTCTGTCTCTCATGTTGTTCCTTATCTCGATAATTTCCTCGC
TTCAGAATAA

Upstream 100 bases:

>100_bases
AACAACACTCATATAAATTGTTTGCTGGCTATTGATAGATGGTAAAAATAGGTGAGGGCAATTATCATTGCGCCAGTCCC
TTTTCGAATGAGTTTCTATT

Downstream 100 bases:

>100_bases
GTAAACATCAGGCATACTCAGTTATGGGTATGCCTGATGTTGAATTCATGTATATTTTATCAATTTAATATGTTGCGATA
ATGTATTTAATTGGCGTGTT

Product: DNA-binding transcriptional activator CadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFARHSGEVLSRDELIDNVWTRSVVTNHVVTQSISELRKSLK
DGDENSPVYIATVPKRGYKLMVPVIWCTEEESEEIMSASPPALPETIPDSASPPAIAETTTPPPQTTTVKRKRFTTFWVW
CFFLLALGTCVALVALSSFETRLPVSKSRILLNPRDIDIHLVNKSPCNNWTSQRSYAVGLGSLVTTSLNTFSTFMVHDKT
NYNIDEPSSSGKTLTIEFVNQRHYRAQQCFMSVKLVDNADGSTMLDKRYFITNDNQLSIQNDLLASLSKALNQPWPQRMQ
EMFQQFQPRRGALLTSFYQAHDYLMRGDVESLSRASELLGEILEEAPDFIYVRAEKALVDVLRHSQHPLDEKQLAALYEE
VDKVGAMPGMNDMSIFYQIKTVSALGSGKIDEAYQAINTGIELEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLRPGE
NTLYWIENGVFQTSVSHVVPYLDNFLASE

Sequences:

>Translated_509_residues
MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFARHSGEVLSRDELIDNVWTRSVVTNHVVTQSISELRKSLK
DGDENSPVYIATVPKRGYKLMVPVIWCTEEESEEIMSASPPALPETIPDSASPPAIAETTTPPPQTTTVKRKRFTTFWVW
CFFLLALGTCVALVALSSFETRLPVSKSRILLNPRDIDIHLVNKSPCNNWTSQRSYAVGLGSLVTTSLNTFSTFMVHDKT
NYNIDEPSSSGKTLTIEFVNQRHYRAQQCFMSVKLVDNADGSTMLDKRYFITNDNQLSIQNDLLASLSKALNQPWPQRMQ
EMFQQFQPRRGALLTSFYQAHDYLMRGDVESLSRASELLGEILEEAPDFIYVRAEKALVDVLRHSQHPLDEKQLAALYEE
VDKVGAMPGMNDMSIFYQIKTVSALGSGKIDEAYQAINTGIELEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLRPGE
NTLYWIENGVFQTSVSHVVPYLDNFLASE
>Mature_509_residues
MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFARHSGEVLSRDELIDNVWTRSVVTNHVVTQSISELRKSLK
DGDENSPVYIATVPKRGYKLMVPVIWCTEEESEEIMSASPPALPETIPDSASPPAIAETTTPPPQTTTVKRKRFTTFWVW
CFFLLALGTCVALVALSSFETRLPVSKSRILLNPRDIDIHLVNKSPCNNWTSQRSYAVGLGSLVTTSLNTFSTFMVHDKT
NYNIDEPSSSGKTLTIEFVNQRHYRAQQCFMSVKLVDNADGSTMLDKRYFITNDNQLSIQNDLLASLSKALNQPWPQRMQ
EMFQQFQPRRGALLTSFYQAHDYLMRGDVESLSRASELLGEILEEAPDFIYVRAEKALVDVLRHSQHPLDEKQLAALYEE
VDKVGAMPGMNDMSIFYQIKTVSALGSGKIDEAYQAINTGIELEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLRPGE
NTLYWIENGVFQTSVSHVVPYLDNFLASE

Specific function: Required for Pcad induction, a promoter upstream of cadB that is responsible for the pH-regulated expression of cadA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790576, Length=514, Percent_Identity=79.9610894941634, Blast_Score=824, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 57545; Mature: 57545

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFARHSGEVLSRDELIDNVWTR
CCCCHHHHCCEEECCCHHHHHCCCCEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SVVTNHVVTQSISELRKSLKDGDENSPVYIATVPKRGYKLMVPVIWCTEEESEEIMSASP
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEEECCCHHHHHHCCCC
PALPETIPDSASPPAIAETTTPPPQTTTVKRKRFTTFWVWCFFLLALGTCVALVALSSFE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLPVSKSRILLNPRDIDIHLVNKSPCNNWTSQRSYAVGLGSLVTTSLNTFSTFMVHDKT
HCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCC
NYNIDEPSSSGKTLTIEFVNQRHYRAQQCFMSVKLVDNADGSTMLDKRYFITNDNQLSIQ
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHEEEEEEECCCCCEEECCEEEEECCCCEEHH
NDLLASLSKALNQPWPQRMQEMFQQFQPRRGALLTSFYQAHDYLMRGDVESLSRASELLG
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EILEEAPDFIYVRAEKALVDVLRHSQHPLDEKQLAALYEEVDKVGAMPGMNDMSIFYQIK
HHHHCCCCEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
TVSALGSGKIDEAYQAINTGIELEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLRPGE
EHHHCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECCCCC
NTLYWIENGVFQTSVSHVVPYLDNFLASE
CEEEEEECCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFARHSGEVLSRDELIDNVWTR
CCCCHHHHCCEEECCCHHHHHCCCCEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SVVTNHVVTQSISELRKSLKDGDENSPVYIATVPKRGYKLMVPVIWCTEEESEEIMSASP
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEEECCCHHHHHHCCCC
PALPETIPDSASPPAIAETTTPPPQTTTVKRKRFTTFWVWCFFLLALGTCVALVALSSFE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLPVSKSRILLNPRDIDIHLVNKSPCNNWTSQRSYAVGLGSLVTTSLNTFSTFMVHDKT
HCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCC
NYNIDEPSSSGKTLTIEFVNQRHYRAQQCFMSVKLVDNADGSTMLDKRYFITNDNQLSIQ
CCCCCCCCCCCCEEEEEECCCHHHHHHHHHEEEEEEECCCCCEEECCEEEEECCCCEEHH
NDLLASLSKALNQPWPQRMQEMFQQFQPRRGALLTSFYQAHDYLMRGDVESLSRASELLG
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
EILEEAPDFIYVRAEKALVDVLRHSQHPLDEKQLAALYEEVDKVGAMPGMNDMSIFYQIK
HHHHCCCCEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEE
TVSALGSGKIDEAYQAINTGIELEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLRPGE
EHHHCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECCCCC
NTLYWIENGVFQTSVSHVVPYLDNFLASE
CEEEEEECCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370290; 7610040; 9278503 [H]