Click here to switch to the map view.

The map label for this gene is mipA [H]

Identifier: 218549151

GI number: 218549151

Start: 1859226

End: 1859972

Strand: Reverse

Name: mipA [H]

Synonym: EFER_1804

Alternate gene names: 218549151

Gene position: 1859972-1859226 (Counterclockwise)

Preceding gene: 218549160

Following gene: 218549150

Centisome position: 40.53

GC content: 52.34

Gene sequence:

>747_bases
GTGACCAAACTCAAACTTCTGGCACTTGGTGTGCTGATCGCAACGTCCGCTGGTGTGGCGCAGGCTGAAAGCAACTTCTC
TCTGGGCGCTGGGGTAGGTGTGGTTGAGCACCCATATAAAGATTATGACACTGACGTGTACCCGGTTCCGGTCATTAACT
ACGAAGGCGATAACTTCTGGTTTCGTGGTTTAGGTGGTGGTTACTACCTGTGGAATGACGCGACGGATAAACTCTCGGTA
ACTGCTTACTGGTCTCCGCTCTATTTCAAAGCGAAAGACAGTGGTGATCACCAAATGCGTCGTCTGGAAGATCGTAAGAG
CACCATGATGGCAGGTCTCTCTTATGCCCACTTCACCCAGTATGGTTACCTGCGTACTACCATTGCCGGTGACACTCTGG
ATAACAGCAATGGACTGGTCTGGGATCTTGCCTGGCTTTATCGTTACACCAACGGTGGCCTGACCCTGACGCCGGGTATC
GGTGTTCAGTGGAACAGCGAAAACCAGAACGAATACTACTACGGTGTTTCGCGCAAAGAGTCTGCCCGCAGTGGTCTGCG
CGGCTATAACCCGAACGATAGCTGGAGCCCGTACCTCGAACTGAGCGCCAACTACAATTTCACTGGTGACTGGAGCGTTT
ACGGTTCAGCACGTTACACTCGCCTGTCTGACGAAGTCACCGACAGCCCGATGGTGGATAAATCCTGGACTGGTCTGATT
TCTGCCGGGATCACGTACAAATTCTGA

Upstream 100 bases:

>100_bases
ACAGTTACCTTGTTAAAGGAATACGCAAAATAGTTGGGTTTAAACATATTGCCGGGTAAACTTTGCCGCCCGTAAACATT
GGTTTAAGGAATAATAGATT

Downstream 100 bases:

>100_bases
TTGTGCTCCTCCAAAGCGCATTTTATGCATAAAAACAGGGCGTCATGCCCTGTTTTGCATTACGGTGGTGCATAAACAAG
GAGGATGTGATGCAAAAGAA

Product: scaffolding protein for murein synthesizing machinery

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTKLKLLALGVLIATSAGVAQAESNFSLGAGVGVVEHPYKDYDTDVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSV
TAYWSPLYFKAKDSGDHQMRRLEDRKSTMMAGLSYAHFTQYGYLRTTIAGDTLDNSNGLVWDLAWLYRYTNGGLTLTPGI
GVQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSANYNFTGDWSVYGSARYTRLSDEVTDSPMVDKSWTGLI
SAGITYKF

Sequences:

>Translated_248_residues
MTKLKLLALGVLIATSAGVAQAESNFSLGAGVGVVEHPYKDYDTDVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSV
TAYWSPLYFKAKDSGDHQMRRLEDRKSTMMAGLSYAHFTQYGYLRTTIAGDTLDNSNGLVWDLAWLYRYTNGGLTLTPGI
GVQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSANYNFTGDWSVYGSARYTRLSDEVTDSPMVDKSWTGLI
SAGITYKF
>Mature_247_residues
TKLKLLALGVLIATSAGVAQAESNFSLGAGVGVVEHPYKDYDTDVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSVT
AYWSPLYFKAKDSGDHQMRRLEDRKSTMMAGLSYAHFTQYGYLRTTIAGDTLDNSNGLVWDLAWLYRYTNGGLTLTPGIG
VQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSANYNFTGDWSVYGSARYTRLSDEVTDSPMVDKSWTGLIS
AGITYKF

Specific function: May serve as a scaffold protein required for the formation of a complex with mrcB/ponB and mltA, this complex could play a role in enlargement and septation of the murein sacculus [H]

COG id: COG3713

COG function: function code M; Outer membrane protein V

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mipA/ompV family [H]

Homologues:

Organism=Escherichia coli, GI1788082, Length=248, Percent_Identity=94.3548387096774, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1790010, Length=245, Percent_Identity=38.3673469387755, Blast_Score=186, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010583 [H]

Pfam domain/function: PF06629 MipA [H]

EC number: NA

Molecular weight: Translated: 27824; Mature: 27693

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLKLLALGVLIATSAGVAQAESNFSLGAGVGVVEHPYKDYDTDVYPVPVINYEGDNFW
CCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCEECCCCCCCCCCEEEEEEEEECCCCEE
FRGLGGGYYLWNDATDKLSVTAYWSPLYFKAKDSGDHQMRRLEDRKSTMMAGLSYAHFTQ
EEECCCCEEEECCCCCEEEEEEEECEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHH
YGYLRTTIAGDTLDNSNGLVWDLAWLYRYTNGGLTLTPGIGVQWNSENQNEYYYGVSRKE
CCEEEEEEECCCCCCCCCEEEEEEEEEEEECCCEEECCCCCEEECCCCCCEEEEECCCCH
SARSGLRGYNPNDSWSPYLELSANYNFTGDWSVYGSARYTRLSDEVTDSPMVDKSWTGLI
HHHHCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCEE
SAGITYKF
ECCEEECC
>Mature Secondary Structure 
TKLKLLALGVLIATSAGVAQAESNFSLGAGVGVVEHPYKDYDTDVYPVPVINYEGDNFW
CCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCEECCCCCCCCCCEEEEEEEEECCCCEE
FRGLGGGYYLWNDATDKLSVTAYWSPLYFKAKDSGDHQMRRLEDRKSTMMAGLSYAHFTQ
EEECCCCEEEECCCCCEEEEEEEECEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHH
YGYLRTTIAGDTLDNSNGLVWDLAWLYRYTNGGLTLTPGIGVQWNSENQNEYYYGVSRKE
CCEEEEEEECCCCCCCCCEEEEEEEEEEEECCCEEECCCCCEEECCCCCCEEEEECCCCH
SARSGLRGYNPNDSWSPYLELSANYNFTGDWSVYGSARYTRLSDEVTDSPMVDKSWTGLI
HHHHCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCEE
SAGITYKF
ECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 10037771; 10806384 [H]