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The map label for this gene is ycgM [H]

Identifier: 218549122

GI number: 218549122

Start: 1827164

End: 1827823

Strand: Reverse

Name: ycgM [H]

Synonym: EFER_1774

Alternate gene names: 218549122

Gene position: 1827823-1827164 (Counterclockwise)

Preceding gene: 218549123

Following gene: 218549121

Centisome position: 39.83

GC content: 49.39

Gene sequence:

>660_bases
ATGTACCAACATCATAACTGGCAAGGTGCGCTGCTCGATTACCCGGTAAGTAAGGTTGTTTGTGTCGGCAGTAATTATGC
CAAACACATCAAGGAGATGGGCAGCGAGACGCCAGAGGAACCGGTGTTGTTTATCAAACCGGAAACGGCATTGTGCGATC
TCCGTCAGCCGCTGGCTATCCCGAGCGATCTTGGTGCTGTCCATCATGAAGTTGAACTGGCTGTACTGATTGGTGCGACC
CTGCGTCAGGCCACAGAAGAGCATGTACGCAAAGCCATTGCGGGTTATGGCGTTGCGTTAGATCTGACGCTGCGTGATAT
TCAGGGAAAAATGAAAAAAGCAGGGCAACCGTGGGAAAAAGCGAAAGCCTTTGATAATTCTTGCCCAATTTCGGGGTTTA
TCCCTGTTGGGGAATTTGACGGTGATCCCCAGAATACATCATTAGGTTTGAAGGTGAACGGTCATGTGCGGCAGCAGGGA
ACTACTGCTGATATGATTCATCAAATTGTTCCGCTTATCGCTTATATGAGTAAGTTCTTCACCCTGAGAGCGGGGGATGT
CGTACTGACTGGAACGCCAGAAGGCGTAGGTCCCCTGGTGAGTGGCGATGAGCTGGAAATCAACGTCAATGGTCATTATT
TGATCACTCGCGTATTGTAA

Upstream 100 bases:

>100_bases
AACAGCATCTTTCTTTGACTGGGCATATCCGTACAGAGAGTGAGCAATAACGGGTAGTCTCCAGGTCATTCCTGAATATC
ACTTAGCGTAGGGGAAAACT

Downstream 100 bases:

>100_bases
TATCTTGTATACAGATTCTGCCGCTCTTTGGGGCGGCAATACTTGCATCGATCTTACGAAGTGGTTATAAGAAGCGCCTT
TATAGCAATGGTGGATACCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSETPEEPVLFIKPETALCDLRQPLAIPSDLGAVHHEVELAVLIGAT
LRQATEEHVRKAIAGYGVALDLTLRDIQGKMKKAGQPWEKAKAFDNSCPISGFIPVGEFDGDPQNTSLGLKVNGHVRQQG
TTADMIHQIVPLIAYMSKFFTLRAGDVVLTGTPEGVGPLVSGDELEINVNGHYLITRVL

Sequences:

>Translated_219_residues
MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSETPEEPVLFIKPETALCDLRQPLAIPSDLGAVHHEVELAVLIGAT
LRQATEEHVRKAIAGYGVALDLTLRDIQGKMKKAGQPWEKAKAFDNSCPISGFIPVGEFDGDPQNTSLGLKVNGHVRQQG
TTADMIHQIVPLIAYMSKFFTLRAGDVVLTGTPEGVGPLVSGDELEINVNGHYLITRVL
>Mature_219_residues
MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSETPEEPVLFIKPETALCDLRQPLAIPSDLGAVHHEVELAVLIGAT
LRQATEEHVRKAIAGYGVALDLTLRDIQGKMKKAGQPWEKAKAFDNSCPISGFIPVGEFDGDPQNTSLGLKVNGHVRQQG
TTADMIHQIVPLIAYMSKFFTLRAGDVVLTGTPEGVGPLVSGDELEINVNGHYLITRVL

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=193, Percent_Identity=46.6321243523316, Blast_Score=186, Evalue=1e-47,
Organism=Homo sapiens, GI215422413, Length=193, Percent_Identity=46.6321243523316, Blast_Score=186, Evalue=1e-47,
Organism=Homo sapiens, GI66348062, Length=193, Percent_Identity=46.6321243523316, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI156231349, Length=199, Percent_Identity=37.1859296482412, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI40786394, Length=213, Percent_Identity=34.7417840375587, Blast_Score=123, Evalue=1e-28,
Organism=Escherichia coli, GI1787428, Length=219, Percent_Identity=88.5844748858447, Blast_Score=410, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17557057, Length=191, Percent_Identity=43.979057591623, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6324161, Length=220, Percent_Identity=35, Blast_Score=137, Evalue=1e-33,
Organism=Drosophila melanogaster, GI28571789, Length=189, Percent_Identity=39.6825396825397, Blast_Score=147, Evalue=5e-36,
Organism=Drosophila melanogaster, GI28572127, Length=180, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24663695, Length=186, Percent_Identity=27.4193548387097, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 23847; Mature: 23847

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSETPEEPVLFIKPETALCDLRQPLAI
CCCCCCCCCCEEECCCCEEEEECCHHHHHHHHHCCCCCCCCEEEECCCHHHHHCCCCCCC
PSDLGAVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDLTLRDIQGKMKKAGQPWEK
CHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHCCCCHHH
AKAFDNSCPISGFIPVGEFDGDPQNTSLGLKVNGHVRQQGTTADMIHQIVPLIAYMSKFF
HHHCCCCCCCCCEEECCCCCCCCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHH
TLRAGDVVLTGTPEGVGPLVSGDELEINVNGHYLITRVL
EEECCCEEEECCCCCCCCCCCCCEEEEEECCEEEEEEEC
>Mature Secondary Structure
MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSETPEEPVLFIKPETALCDLRQPLAI
CCCCCCCCCCEEECCCCEEEEECCHHHHHHHHHCCCCCCCCEEEECCCHHHHHCCCCCCC
PSDLGAVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDLTLRDIQGKMKKAGQPWEK
CHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHCCCCHHH
AKAFDNSCPISGFIPVGEFDGDPQNTSLGLKVNGHVRQQGTTADMIHQIVPLIAYMSKFF
HHHCCCCCCCCCEEECCCCCCCCCCCEEEEEECCEEECCCCHHHHHHHHHHHHHHHHHHH
TLRAGDVVLTGTPEGVGPLVSGDELEINVNGHYLITRVL
EEECCCEEEECCCCCCCCCCCCCEEEEEECCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]