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The map label for this gene is ldcA [H]

Identifier: 218549111

GI number: 218549111

Start: 1812275

End: 1813189

Strand: Direct

Name: ldcA [H]

Synonym: EFER_1763

Alternate gene names: 218549111

Gene position: 1812275-1813189 (Clockwise)

Preceding gene: 218549109

Following gene: 218549112

Centisome position: 39.49

GC content: 47.65

Gene sequence:

>915_bases
ATGTCTCTGTTTCATTTAATTGCTCCATCAGGTTATTGCATCAATCAAGAGGCCGCCTGGCGCGGTGTTCAACGCCTGAC
AGAAGCTGGTCATCAGGTGAATAATTCAGACGTTATTTACCGACGCTATCAACGTTTTGCTGGTACAGAGACAGAGCGGC
TGGCAGATATCAATGCCCTCGCCCATCTTGATCTCCCCAATACCATCGTACTGGCCGTACGTGGTGGTTATGGTGCCAGT
CGAATCCTGGCCGGGATCGACTGGTCGGCATTGATTGCACGGCAGTTGCATAACCCATTACTCATTTGTGGGCACAGTGA
TTTCACTGCAATTCAGTGTGGGTTACTGGCAAAAGGCAACGTGATTACTTTCAGCGGCCCCATGCTGGCAGCAAATTTTG
GCGCAGAAACACTCAATGAGTTTACGGCTCACCATTTCTGGCTGGCATTGCGTAACAAAACATTCACCGTCGAGTGGCAA
GGTGAAGGCCCTTCTTGTCAGACAGAAGGAACATTGTGGGGGGGAAATCTGGCAATGTTGATTTCATTAATAGGCACTCC
GTGGATGCCAAATATCAGTAACGGCATTCTGGTTCTGGAGGATATTAATGAACATCCATTCCGGGTTGAGCGGATGCTAT
TACAGTTACTTGAAGCTGGAATATTAGATCGTCAAAAAGGGATTGTTCTCGGTAGTTTTAGCGGTAGTGCTCCCAATGAT
TACGATGCCGGTTATTCCCTGCAAAGTGTGTTTGATTTTCTGCGGTCACGCCTCTCTGTTCCACTGCTTACTGGGTTAGA
TTTCGGTCATGAGCAACGCACGGTCACTTTACCTTTGGGGGCTCACGCAGTACTGAGAAATAATCAAAATGGCACCCAGT
TAATCCTTAGCGGTCATCCTGTTCTGAAATCTTAA

Upstream 100 bases:

>100_bases
ACTTCGTCTATCCTTATGCCGGAATTTGTCTCTGAGGTGACAACACAATACCTACGCGGCATGATATACATTTGCATTCA
GTTGTCAGCAAGGAATTGCC

Downstream 100 bases:

>100_bases
AAAAAACGTGAATAAGCGTTAACTATCCCGCTGTTTCGGTCGTTAATATGGTAGTGTTGTTACTACGAAACAGCGTAATT
TGGGAGAAACATAACGTTGG

Product: L,D-carboxypeptidase A

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSLFHLIAPSGYCINQEAAWRGVQRLTEAGHQVNNSDVIYRRYQRFAGTETERLADINALAHLDLPNTIVLAVRGGYGAS
RILAGIDWSALIARQLHNPLLICGHSDFTAIQCGLLAKGNVITFSGPMLAANFGAETLNEFTAHHFWLALRNKTFTVEWQ
GEGPSCQTEGTLWGGNLAMLISLIGTPWMPNISNGILVLEDINEHPFRVERMLLQLLEAGILDRQKGIVLGSFSGSAPND
YDAGYSLQSVFDFLRSRLSVPLLTGLDFGHEQRTVTLPLGAHAVLRNNQNGTQLILSGHPVLKS

Sequences:

>Translated_304_residues
MSLFHLIAPSGYCINQEAAWRGVQRLTEAGHQVNNSDVIYRRYQRFAGTETERLADINALAHLDLPNTIVLAVRGGYGAS
RILAGIDWSALIARQLHNPLLICGHSDFTAIQCGLLAKGNVITFSGPMLAANFGAETLNEFTAHHFWLALRNKTFTVEWQ
GEGPSCQTEGTLWGGNLAMLISLIGTPWMPNISNGILVLEDINEHPFRVERMLLQLLEAGILDRQKGIVLGSFSGSAPND
YDAGYSLQSVFDFLRSRLSVPLLTGLDFGHEQRTVTLPLGAHAVLRNNQNGTQLILSGHPVLKS
>Mature_303_residues
SLFHLIAPSGYCINQEAAWRGVQRLTEAGHQVNNSDVIYRRYQRFAGTETERLADINALAHLDLPNTIVLAVRGGYGASR
ILAGIDWSALIARQLHNPLLICGHSDFTAIQCGLLAKGNVITFSGPMLAANFGAETLNEFTAHHFWLALRNKTFTVEWQG
EGPSCQTEGTLWGGNLAMLISLIGTPWMPNISNGILVLEDINEHPFRVERMLLQLLEAGILDRQKGIVLGSFSGSAPNDY
DAGYSLQSVFDFLRSRLSVPLLTGLDFGHEQRTVTLPLGAHAVLRNNQNGTQLILSGHPVLKS

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=303, Percent_Identity=82.1782178217822, Blast_Score=525, Evalue=1e-150,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 33296; Mature: 33164

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFHLIAPSGYCINQEAAWRGVQRLTEAGHQVNNSDVIYRRYQRFAGTETERLADINAL
CCEEEEECCCCCEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHE
AHLDLPNTIVLAVRGGYGASRILAGIDWSALIARQLHNPLLICGHSDFTAIQCGLLAKGN
EECCCCCEEEEEEECCCCHHHHHCCCCHHHHHHHHHCCCEEEECCCCCCEEEECEEECCC
VITFSGPMLAANFGAETLNEFTAHHFWLALRNKTFTVEWQGEGPSCQTEGTLWGGNLAML
EEEECCCEEEECCCHHHHHHHHHHEEEEEEECCEEEEEECCCCCCCCCCCEEECCHHHHH
ISLIGTPWMPNISNGILVLEDINEHPFRVERMLLQLLEAGILDRQKGIVLGSFSGSAPND
HHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCC
YDAGYSLQSVFDFLRSRLSVPLLTGLDFGHEQRTVTLPLGAHAVLRNNQNGTQLILSGHP
CCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCCEEEEECCCCCCEEEEECCC
VLKS
CCCC
>Mature Secondary Structure 
SLFHLIAPSGYCINQEAAWRGVQRLTEAGHQVNNSDVIYRRYQRFAGTETERLADINAL
CEEEEECCCCCEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHE
AHLDLPNTIVLAVRGGYGASRILAGIDWSALIARQLHNPLLICGHSDFTAIQCGLLAKGN
EECCCCCEEEEEEECCCCHHHHHCCCCHHHHHHHHHCCCEEEECCCCCCEEEECEEECCC
VITFSGPMLAANFGAETLNEFTAHHFWLALRNKTFTVEWQGEGPSCQTEGTLWGGNLAML
EEEECCCEEEECCCHHHHHHHHHHEEEEEEECCEEEEEECCCCCCCCCCCEEECCHHHHH
ISLIGTPWMPNISNGILVLEDINEHPFRVERMLLQLLEAGILDRQKGIVLGSFSGSAPND
HHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCC
YDAGYSLQSVFDFLRSRLSVPLLTGLDFGHEQRTVTLPLGAHAVLRNNQNGTQLILSGHP
CCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEECCCEEEEECCCCCCEEEEECCC
VLKS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]