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The map label for this gene is yciA [H]

Identifier: 218549054

GI number: 218549054

Start: 1749039

End: 1749437

Strand: Direct

Name: yciA [H]

Synonym: EFER_1701

Alternate gene names: 218549054

Gene position: 1749039-1749437 (Clockwise)

Preceding gene: 218549053

Following gene: 218549056

Centisome position: 38.12

GC content: 47.87

Gene sequence:

>399_bases
ATGACAACAACAAATAACGTCCCTCAGGGCGATCTGGTTTTACGCACTCTGGCAATGCCAGCTGATACCAATGCCAACGG
TGATATTTTTGGTGGTTGGTTAATGTCACAAATGGATATTGGTGGCGCCATTCTGGCAAAAGAAATTGCGCACGGTCGTG
TGGTGACTGTTCGCGTCGAAGGAATGACTTTTTTACGTCCAGTTGCGGTCGGTGATGTGGTGTGCTGCTACGCACGCTGT
GTTAATAAAGGCACTACTTCGGTCAGCATTAATATTGAAGTTTGGGTGAAGAAAGTCGCTTCCGAACCGATTGGACAGCG
CTATAAAGCCACTGAGGCGTTGTTTAAATATGTTGCAGTGGATCCCGATGGAAAACCTCGACCACTGCCCGTACCGTAA

Upstream 100 bases:

>100_bases
GCCAGTCCTGCAGGGCTGGCGCTTTCTTTTCACCTCTGTTCTCGTTTCGCAAATCATAGTAGCATCGCGCCTGTAATCTT
TCTTTTAAGTCGGTTCTAGC

Downstream 100 bases:

>100_bases
TAGCAAAAGCCTCCTGTCCGGAGGCTTTTGTTTTTTATGGCTGATTATTGGATTTGGGTTGCTCCATTCATCCGGAACAA
AATATTAACCACAATTCCAC

Product: acyl-CoA thioester hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MTTTNNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAILAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARC
VNKGTTSVSINIEVWVKKVASEPIGQRYKATEALFKYVAVDPDGKPRPLPVP

Sequences:

>Translated_132_residues
MTTTNNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAILAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARC
VNKGTTSVSINIEVWVKKVASEPIGQRYKATEALFKYVAVDPDGKPRPLPVP
>Mature_131_residues
TTTNNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAILAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCV
NKGTTSVSINIEVWVKKVASEPIGQRYKATEALFKYVAVDPDGKPRPLPVP

Specific function: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA [H]

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1787506, Length=131, Percent_Identity=96.1832061068702, Blast_Score=261, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 14188; Mature: 14056

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTNNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAILAKEIAHGRVVTVRVE
CCCCCCCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHHCCCHHHHHHHHCCCCEEEEEEC
GMTFLRPVAVGDVVCCYARCVNKGTTSVSINIEVWVKKVASEPIGQRYKATEALFKYVAV
CEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHEEE
DPDGKPRPLPVP
CCCCCCCCCCCC
>Mature Secondary Structure 
TTTNNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAILAKEIAHGRVVTVRVE
CCCCCCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHHCCCHHHHHHHHCCCCEEEEEEC
GMTFLRPVAVGDVVCCYARCVNKGTTSVSINIEVWVKKVASEPIGQRYKATEALFKYVAV
CEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHEEE
DPDGKPRPLPVP
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]