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The map label for this gene is yciR [C]

Identifier: 218548797

GI number: 218548797

Start: 1477835

End: 1480003

Strand: Direct

Name: yciR [C]

Synonym: EFER_1436

Alternate gene names: 218548797

Gene position: 1477835-1480003 (Clockwise)

Preceding gene: 218548796

Following gene: 218548801

Centisome position: 32.21

GC content: 46.66

Gene sequence:

>2169_bases
GTGAGAATGGCTAACTGGCTGCACTGGCGTAATATACCAACTGCAAAAACGTTGTTTGTGATGATTTTTATCGCCGGGAT
CGGGTTAATCATCTCGGTTGTGGCATTACTTTATCTGTCGTTACATCTAATCAGCTCTAAAGCTAATGAGATTGATAATC
GGCGTGCTGCATTATCCGTCGAAGGGGCAATACAGACTTCGGTATTTCGAGTGTCATCGTTAGTACTGGATAATGCCGTC
TGGGACGAAGCAGTGAAAGAAACGTATCGATCCGAACTTAATACTGACTGGTTATACAACACCTGGGGATCAGGTTTTAA
AGTTAATAACCTTTATGACGGTACATTTGTCCTTAATGAAAATTTCGAGGTGCTCTGGGGGGCATTTCGCGGTGAAACGT
TAAGGGGAAATGAACGCCATTTTTTTGGTAAAGGGATCGAAGCGTTAATTGATAAACATGCAGATGCGTTAAAAAACGGC
AAAAATATCTATTCGGGGATCACCCGCACTCAGGCTGGAATTGCCTTTGTGGGCATCGGTTTGATTCGCCCTATGGCTGA
AGCTTTCTCTTTTACACAGCCTTCTCGCCGCTATTTACTGATCACCCGGCATTTAAATAACAATATTCTGCACGCGTTGG
GTAATACCTTTCAAATTGCCCATCTTTCATACAGCGAAAATGAACCTGGTACACCTCATATTCCGCTCACCAGTTCAGCC
GGAGAATTATTAGGTTATCTCAGTTGGCAACCACGACTTCCTGGGGCTCAGGCAGCCGATGCGGCATCAAGTCAGATTAC
ACAAATAGTGGCACTGGCATCGGCGCTCATTCTGTTATTTATATTGCTCAGCAGCGTGGGGCTATACAAATTAGCCCACG
GCGAACAGAAGGCGAGGCGGATTGCCCGCATTGACTGGTTGAGTCGTTTACCAAATCGTCGTGCTTTAATTGAAACACTG
GAAGATTTACGTAAACGTGGAGAATGTGATCTCAAAAGTGTTGTGTTTATTGATCTCGATGGCTTTAAAGACATCAATGA
TATCTACGGACATTATGTTGGCGATCAGTTGATCATCTCCCTTGCCCAGACGTTACAGGTATTAACACCGAAAGACGGAA
TGCTGGCGCGGATGGGCGGTGATGAGTTTGCGCTGATGATCGGCGGTAAAAAATCAGAGCAAATAGCGACGGAATTTGCA
GATAAGGTAATGAAATATCTTAATAATCCTGTACAGCTGGGTGAGCGTTCTATTCACATTAGTGCCAGTATTGGTATTGC
CAGTGGTTCACTGGTTGAATGCACCAGTTCGGAGTTATTTCGTCGGGCGGATATCGCTATGTATCACGCGAAAGCAACGG
GCAAAGGGCGCATTACGCATTACGATGCTGAACTCAATAGCGCTCGGGAACGGCAACTGACAATCGAGAACGATATTCGA
CTGGGGCTGGAAAGAAATGAATTTGACGTCTGGTATCAGCCAATCGTCGATGCCCGCACACAGTTAATGGTGGGGGTTGA
AGGGCTGGTTCGCTGGAAGCGACGTCCTGCAGGAGAACTTCGTCCAGATGATTTTATCCCTGTTGCCGAAACAAGTGGTC
TCATTGACGCTCTGGGGCAATTCGTATTACGCCGAGCCTGTTATGATCTTCATCCTCTGAGTGAGCTTAAACTGTCGGTA
AATATCTCCCCGGCACAGTTTCGTGATCCCGAATTTGAAGACAAAGTCGCCGGCGTCTTAAACGAAACATGTTTCCCGGC
CTCCCGTTTACAACTGGAAGTCACTGAAACCTACGTTCTGGAGAATCCAGACCGCGCGAAATCAGCAATTGCTAACCTGA
AAGCACTGGGTACAGCTATTGCTCTGGATGATTTTGGCACTGGATATTCCAGTATTGGGTATTTGCGGCGATTTAATTTC
GATGCCATCAAAATTGATAAATCTCTGGCTGGACTGGTGGATAATGACGATCAGGCTGCGGCACTGGTTAGCGGAACGGT
ACGTATTGCCAGTGCGTTAGGCATGTTGGTGACTGCGGAAGGCGTGGAGACAGAGAAACAGATGAAACTATTACGCCTGG
CTGGCTGCGACCGTTTACAGGGCTTTTATTTCAGCCAGCCGATGCCGATAGAATCACTGATGCAATTACGCCAGCAGCGT
CATTGCTGA

Upstream 100 bases:

>100_bases
GTAAATACGCAGATTTAATTTTTGCTCTCATGAAATGCAGCTAAATTCTTAGCCTGTATTACGCTATAAGTACTAGTCCT
CGTCAGATAACGCATGAGAC

Downstream 100 bases:

>100_bases
GCCAGAGCCTGTAATTTTTCACGAAATCCGGTGACTGAAATAGCGCGATTGTCTGCACGCCAGCGATCTTTTGCCGCTGG
TGCCGAACTTTGTACGCCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 722; Mature: 722

Protein sequence:

>722_residues
MRMANWLHWRNIPTAKTLFVMIFIAGIGLIISVVALLYLSLHLISSKANEIDNRRAALSVEGAIQTSVFRVSSLVLDNAV
WDEAVKETYRSELNTDWLYNTWGSGFKVNNLYDGTFVLNENFEVLWGAFRGETLRGNERHFFGKGIEALIDKHADALKNG
KNIYSGITRTQAGIAFVGIGLIRPMAEAFSFTQPSRRYLLITRHLNNNILHALGNTFQIAHLSYSENEPGTPHIPLTSSA
GELLGYLSWQPRLPGAQAADAASSQITQIVALASALILLFILLSSVGLYKLAHGEQKARRIARIDWLSRLPNRRALIETL
EDLRKRGECDLKSVVFIDLDGFKDINDIYGHYVGDQLIISLAQTLQVLTPKDGMLARMGGDEFALMIGGKKSEQIATEFA
DKVMKYLNNPVQLGERSIHISASIGIASGSLVECTSSELFRRADIAMYHAKATGKGRITHYDAELNSARERQLTIENDIR
LGLERNEFDVWYQPIVDARTQLMVGVEGLVRWKRRPAGELRPDDFIPVAETSGLIDALGQFVLRRACYDLHPLSELKLSV
NISPAQFRDPEFEDKVAGVLNETCFPASRLQLEVTETYVLENPDRAKSAIANLKALGTAIALDDFGTGYSSIGYLRRFNF
DAIKIDKSLAGLVDNDDQAAALVSGTVRIASALGMLVTAEGVETEKQMKLLRLAGCDRLQGFYFSQPMPIESLMQLRQQR
HC

Sequences:

>Translated_722_residues
MRMANWLHWRNIPTAKTLFVMIFIAGIGLIISVVALLYLSLHLISSKANEIDNRRAALSVEGAIQTSVFRVSSLVLDNAV
WDEAVKETYRSELNTDWLYNTWGSGFKVNNLYDGTFVLNENFEVLWGAFRGETLRGNERHFFGKGIEALIDKHADALKNG
KNIYSGITRTQAGIAFVGIGLIRPMAEAFSFTQPSRRYLLITRHLNNNILHALGNTFQIAHLSYSENEPGTPHIPLTSSA
GELLGYLSWQPRLPGAQAADAASSQITQIVALASALILLFILLSSVGLYKLAHGEQKARRIARIDWLSRLPNRRALIETL
EDLRKRGECDLKSVVFIDLDGFKDINDIYGHYVGDQLIISLAQTLQVLTPKDGMLARMGGDEFALMIGGKKSEQIATEFA
DKVMKYLNNPVQLGERSIHISASIGIASGSLVECTSSELFRRADIAMYHAKATGKGRITHYDAELNSARERQLTIENDIR
LGLERNEFDVWYQPIVDARTQLMVGVEGLVRWKRRPAGELRPDDFIPVAETSGLIDALGQFVLRRACYDLHPLSELKLSV
NISPAQFRDPEFEDKVAGVLNETCFPASRLQLEVTETYVLENPDRAKSAIANLKALGTAIALDDFGTGYSSIGYLRRFNF
DAIKIDKSLAGLVDNDDQAAALVSGTVRIASALGMLVTAEGVETEKQMKLLRLAGCDRLQGFYFSQPMPIESLMQLRQQR
HC
>Mature_722_residues
MRMANWLHWRNIPTAKTLFVMIFIAGIGLIISVVALLYLSLHLISSKANEIDNRRAALSVEGAIQTSVFRVSSLVLDNAV
WDEAVKETYRSELNTDWLYNTWGSGFKVNNLYDGTFVLNENFEVLWGAFRGETLRGNERHFFGKGIEALIDKHADALKNG
KNIYSGITRTQAGIAFVGIGLIRPMAEAFSFTQPSRRYLLITRHLNNNILHALGNTFQIAHLSYSENEPGTPHIPLTSSA
GELLGYLSWQPRLPGAQAADAASSQITQIVALASALILLFILLSSVGLYKLAHGEQKARRIARIDWLSRLPNRRALIETL
EDLRKRGECDLKSVVFIDLDGFKDINDIYGHYVGDQLIISLAQTLQVLTPKDGMLARMGGDEFALMIGGKKSEQIATEFA
DKVMKYLNNPVQLGERSIHISASIGIASGSLVECTSSELFRRADIAMYHAKATGKGRITHYDAELNSARERQLTIENDIR
LGLERNEFDVWYQPIVDARTQLMVGVEGLVRWKRRPAGELRPDDFIPVAETSGLIDALGQFVLRRACYDLHPLSELKLSV
NISPAQFRDPEFEDKVAGVLNETCFPASRLQLEVTETYVLENPDRAKSAIANLKALGTAIALDDFGTGYSSIGYLRRFNF
DAIKIDKSLAGLVDNDDQAAALVSGTVRIASALGMLVTAEGVETEKQMKLLRLAGCDRLQGFYFSQPMPIESLMQLRQQR
HC

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=435, Percent_Identity=33.7931034482759, Blast_Score=248, Evalue=1e-66,
Organism=Escherichia coli, GI87081921, Length=504, Percent_Identity=26.5873015873016, Blast_Score=189, Evalue=6e-49,
Organism=Escherichia coli, GI226510982, Length=429, Percent_Identity=29.3706293706294, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI1786507, Length=250, Percent_Identity=34, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1788502, Length=251, Percent_Identity=32.6693227091633, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1790496, Length=255, Percent_Identity=29.8039215686275, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI87081980, Length=245, Percent_Identity=34.2857142857143, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1787055, Length=258, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI87081845, Length=251, Percent_Identity=32.2709163346614, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI87081743, Length=245, Percent_Identity=30.2040816326531, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1788849, Length=441, Percent_Identity=25.3968253968254, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI87082096, Length=420, Percent_Identity=23.5714285714286, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1788381, Length=182, Percent_Identity=32.4175824175824, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786584, Length=183, Percent_Identity=30.6010928961749, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787802, Length=168, Percent_Identity=30.952380952381, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1787056, Length=160, Percent_Identity=31.25, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI87081977, Length=200, Percent_Identity=32.5, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87081881, Length=170, Percent_Identity=31.7647058823529, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787262, Length=205, Percent_Identity=26.3414634146341, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=29.4478527607362, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787410, Length=229, Percent_Identity=26.6375545851528, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=33.9622641509434, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788956, Length=155, Percent_Identity=31.6129032258064, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI1789650, Length=409, Percent_Identity=22.0048899755501, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788085, Length=180, Percent_Identity=26.6666666666667, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 80268; Mature: 80268

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMANWLHWRNIPTAKTLFVMIFIAGIGLIISVVALLYLSLHLISSKANEIDNRRAALSV
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
EGAIQTSVFRVSSLVLDNAVWDEAVKETYRSELNTDWLYNTWGSGFKVNNLYDGTFVLNE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECEEECCEEEECC
NFEVLWGAFRGETLRGNERHFFGKGIEALIDKHADALKNGKNIYSGITRTQAGIAFVGIG
CCCEEEEECCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHH
LIRPMAEAFSFTQPSRRYLLITRHLNNNILHALGNTFQIAHLSYSENEPGTPHIPLTSSA
HHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCH
GELLGYLSWQPRLPGAQAADAASSQITQIVALASALILLFILLSSVGLYKLAHGEQKARR
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHH
IARIDWLSRLPNRRALIETLEDLRKRGECDLKSVVFIDLDGFKDINDIYGHYVGDQLIIS
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
LAQTLQVLTPKDGMLARMGGDEFALMIGGKKSEQIATEFADKVMKYLNNPVQLGERSIHI
HHHHHHHCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHCCCCEEEE
SASIGIASGSLVECTSSELFRRADIAMYHAKATGKGRITHYDAELNSARERQLTIENDIR
EEEEEECCCCEEECCHHHHHHHHHHHEEEECCCCCCCEEEECCHHCCCHHHEEEEECCEE
LGLERNEFDVWYQPIVDARTQLMVGVEGLVRWKRRPAGELRPDDFIPVAETSGLIDALGQ
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCHHHHHHHH
FVLRRACYDLHPLSELKLSVNISPAQFRDPEFEDKVAGVLNETCFPASRLQLEVTETYVL
HHHHHHHHCCCCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHCCCCCHHEEEEEEEEEEE
ENPDRAKSAIANLKALGTAIALDDFGTGYSSIGYLRRFNFDAIKIDKSLAGLVDNDDQAA
CCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCEEEECHHHHCCCCCCCCHH
ALVSGTVRIASALGMLVTAEGVETEKQMKLLRLAGCDRLQGFYFSQPMPIESLMQLRQQR
HHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCHHHCCEECCCCCCHHHHHHHHHHC
HC
CC
>Mature Secondary Structure
MRMANWLHWRNIPTAKTLFVMIFIAGIGLIISVVALLYLSLHLISSKANEIDNRRAALSV
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
EGAIQTSVFRVSSLVLDNAVWDEAVKETYRSELNTDWLYNTWGSGFKVNNLYDGTFVLNE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEECEEECCEEEECC
NFEVLWGAFRGETLRGNERHFFGKGIEALIDKHADALKNGKNIYSGITRTQAGIAFVGIG
CCCEEEEECCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHH
LIRPMAEAFSFTQPSRRYLLITRHLNNNILHALGNTFQIAHLSYSENEPGTPHIPLTSSA
HHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCH
GELLGYLSWQPRLPGAQAADAASSQITQIVALASALILLFILLSSVGLYKLAHGEQKARR
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHH
IARIDWLSRLPNRRALIETLEDLRKRGECDLKSVVFIDLDGFKDINDIYGHYVGDQLIIS
HHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
LAQTLQVLTPKDGMLARMGGDEFALMIGGKKSEQIATEFADKVMKYLNNPVQLGERSIHI
HHHHHHHCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHCCCCEEEE
SASIGIASGSLVECTSSELFRRADIAMYHAKATGKGRITHYDAELNSARERQLTIENDIR
EEEEEECCCCEEECCHHHHHHHHHHHEEEECCCCCCCEEEECCHHCCCHHHEEEEECCEE
LGLERNEFDVWYQPIVDARTQLMVGVEGLVRWKRRPAGELRPDDFIPVAETSGLIDALGQ
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCHHHHHHHH
FVLRRACYDLHPLSELKLSVNISPAQFRDPEFEDKVAGVLNETCFPASRLQLEVTETYVL
HHHHHHHHCCCCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHCCCCCHHEEEEEEEEEEE
ENPDRAKSAIANLKALGTAIALDDFGTGYSSIGYLRRFNFDAIKIDKSLAGLVDNDDQAA
CCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCEEEECHHHHCCCCCCCCHH
ALVSGTVRIASALGMLVTAEGVETEKQMKLLRLAGCDRLQGFYFSQPMPIESLMQLRQQR
HHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCHHHCCEECCCCCCHHHHHHHHHHC
HC
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]