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The map label for this gene is tus

Identifier: 218548788

GI number: 218548788

Start: 1467397

End: 1468326

Strand: Reverse

Name: tus

Synonym: EFER_1427

Alternate gene names: 218548788

Gene position: 1468326-1467397 (Counterclockwise)

Preceding gene: 218548789

Following gene: 218548785

Centisome position: 32.0

GC content: 47.85

Gene sequence:

>930_bases
ATGGCCCGTTACGATCTTGTTGACCGACTCAATACTACTTTTCGTCAAATGGAGCTGGCGCTGGCGACCTTTGTTGCAGA
GCTTGAACAGCACAGGTTGCTGATCGCCCGCGTATTTTCATTACCCGAAGTCAAAAAAGAGGATGAACATAACCCACTGG
AACAGATCGAGGTAAAACAACATTTGGGAACAGAGGCTGAATCTTTGGCGTTGCGCCATTTTCGCCATTTGTTTATCCAA
CAACAGTCTGAAAACCGTAGTAGCAAAGCTGCAGTAAGATTGCCCGGAGTCATCTGTTATCAGGTTGATGACAATACTCG
TCCCCTGCTTGAAGAACACGTTAAACGCATCAATGAATTAAAAATGGCCTTTGAGCACATTGTCACAGTGGAGTCTGGTT
TACCAACAGCAGCGCGTTTTGAGTGGGTACACCGCCACTTGCCAGGTCTCATAACGCTTAACGCTTATCGAACGTTGACG
GTTATTAACGATCCGGCGACCTTACGTTTTGGTTGGGCGAACAAACATATTATTAAGAACTTACGACGCGACGACGTACT
GGCGCAACTTGAGAAAAGCCTCAAATCACCGCGTAGCGTTTACCCATGGACACGGGAAGAGTGGCAGGCAAAACTGGAAC
GCGAGTATCAGGATATCGCCTCTCTGCCCCAGGAGGCGAAATTAAAAATTAAACGGCCAGTAAAGGTACAGCCTATTGCC
CGCGTCTGGTATAAGGGCGATCAAAAGCAAGTACAACATGCCTGCCCTACGCCGCTTATTGCCTTAATTAATACCGACAA
TGGTGCCGGGGTGCCGGATATTGGCGAATTACTCAATTACGACGCCGCGAATGTTCAGCATCGCTATAAACCACAGGCGC
AGCCGCTTCGTTTAATCATTCCACGACTGCATCTGTATGTAGCTGATTAG

Upstream 100 bases:

>100_bases
GAAATAAATGCATAAATCCCTGCCAGACCATGACCGCACGGTGGTGATGTCCGGCATGTTGTGATATACATAAAGTATGT
TGTAACTAAATGGTGGTTTT

Downstream 100 bases:

>100_bases
TGGTTTTGTTGCATACTTCCAACCATCTGTTCAGGGCGTACCCAACTGTCGAATTCAGCTTCGCTCAGATATCCCAACGC
CAGGGCTGCTGCTTTTAATG

Product: DNA replication terminus site-binding protein

Products: NA

Alternate protein names: Ter-binding protein

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MARYDLVDRLNTTFRQMELALATFVAELEQHRLLIARVFSLPEVKKEDEHNPLEQIEVKQHLGTEAESLALRHFRHLFIQ
QQSENRSSKAAVRLPGVICYQVDDNTRPLLEEHVKRINELKMAFEHIVTVESGLPTAARFEWVHRHLPGLITLNAYRTLT
VINDPATLRFGWANKHIIKNLRRDDVLAQLEKSLKSPRSVYPWTREEWQAKLEREYQDIASLPQEAKLKIKRPVKVQPIA
RVWYKGDQKQVQHACPTPLIALINTDNGAGVPDIGELLNYDAANVQHRYKPQAQPLRLIIPRLHLYVAD

Sequences:

>Translated_309_residues
MARYDLVDRLNTTFRQMELALATFVAELEQHRLLIARVFSLPEVKKEDEHNPLEQIEVKQHLGTEAESLALRHFRHLFIQ
QQSENRSSKAAVRLPGVICYQVDDNTRPLLEEHVKRINELKMAFEHIVTVESGLPTAARFEWVHRHLPGLITLNAYRTLT
VINDPATLRFGWANKHIIKNLRRDDVLAQLEKSLKSPRSVYPWTREEWQAKLEREYQDIASLPQEAKLKIKRPVKVQPIA
RVWYKGDQKQVQHACPTPLIALINTDNGAGVPDIGELLNYDAANVQHRYKPQAQPLRLIIPRLHLYVAD
>Mature_308_residues
ARYDLVDRLNTTFRQMELALATFVAELEQHRLLIARVFSLPEVKKEDEHNPLEQIEVKQHLGTEAESLALRHFRHLFIQQ
QSENRSSKAAVRLPGVICYQVDDNTRPLLEEHVKRINELKMAFEHIVTVESGLPTAARFEWVHRHLPGLITLNAYRTLTV
INDPATLRFGWANKHIIKNLRRDDVLAQLEKSLKSPRSVYPWTREEWQAKLEREYQDIASLPQEAKLKIKRPVKVQPIAR
VWYKGDQKQVQHACPTPLIALINTDNGAGVPDIGELLNYDAANVQHRYKPQAQPLRLIIPRLHLYVAD

Specific function: Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tus family

Homologues:

Organism=Escherichia coli, GI1787895, Length=309, Percent_Identity=87.378640776699, Blast_Score=560, Evalue=1e-161,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TUS_ESCF3 (B7LQQ4)

Other databases:

- EMBL:   CU928158
- RefSeq:   YP_002382579.1
- EnsemblBacteria:   EBESCT00000124698
- GeneID:   7120155
- GenomeReviews:   CU928158_GR
- KEGG:   efe:EFER_1427
- GeneTree:   EBGT00050000011457
- HOGENOM:   HBG416199
- ProtClustDB:   PRK02951
- BioCyc:   EFER585054:EFER_1427-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00483
- InterPro:   IPR008865
- Gene3D:   G3DSA:3.50.14.10
- TIGRFAMs:   TIGR02648

Pfam domain/function: PF05472 Ter; SSF56596 Rep_term_tus

EC number: NA

Molecular weight: Translated: 35803; Mature: 35672

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARYDLVDRLNTTFRQMELALATFVAELEQHRLLIARVFSLPEVKKEDEHNPLEQIEVKQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
HLGTEAESLALRHFRHLFIQQQSENRSSKAAVRLPGVICYQVDDNTRPLLEEHVKRINEL
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHH
KMAFEHIVTVESGLPTAARFEWVHRHLPGLITLNAYRTLTVINDPATLRFGWANKHIIKN
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECEEEEEEECCCCEEEECCCCHHHHHH
LRRDDVLAQLEKSLKSPRSVYPWTREEWQAKLEREYQDIASLPQEAKLKIKRPVKVQPIA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCEEECCCCCCCHHH
RVWYKGDQKQVQHACPTPLIALINTDNGAGVPDIGELLNYDAANVQHRYKPQAQPLRLII
HHHHCCCHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCHHHCCCCCCHHHHHC
PRLHLYVAD
CHHEEEECC
>Mature Secondary Structure 
ARYDLVDRLNTTFRQMELALATFVAELEQHRLLIARVFSLPEVKKEDEHNPLEQIEVKQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
HLGTEAESLALRHFRHLFIQQQSENRSSKAAVRLPGVICYQVDDNTRPLLEEHVKRINEL
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHH
KMAFEHIVTVESGLPTAARFEWVHRHLPGLITLNAYRTLTVINDPATLRFGWANKHIIKN
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECEEEEEEECCCCEEEECCCCHHHHHH
LRRDDVLAQLEKSLKSPRSVYPWTREEWQAKLEREYQDIASLPQEAKLKIKRPVKVQPIA
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCEEECCCCCCCHHH
RVWYKGDQKQVQHACPTPLIALINTDNGAGVPDIGELLNYDAANVQHRYKPQAQPLRLII
HHHHCCCHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCHHHCCCCCCHHHHHC
PRLHLYVAD
CHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA