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The map label for this gene is anmK

Identifier: 218548764

GI number: 218548764

Start: 1442309

End: 1443433

Strand: Direct

Name: anmK

Synonym: EFER_1403

Alternate gene names: 218548764

Gene position: 1442309-1443433 (Clockwise)

Preceding gene: 218548762

Following gene: 218548765

Centisome position: 31.43

GC content: 53.24

Gene sequence:

>1125_bases
ATGAGATCCGGTCGTTATATTGGCGTTATGTCAGGAACCAGCCTTGATGGAGTTGATGTGGTGCTGGCGGCGATAGATGA
AAACATGGTGGCGCAGCAAGCCAGCCTGAGTTGGCCTATCCCGGTCGAACTCAAACAGGCCGTGCTGGATATTTGCCAGG
GCCAACAACTCACACTTTCTCAGTTTGGACAACTCGATACCCGATTAGGCATCTTGTTTGCTGATGCCGTAAATGGTTTG
CTGGCACAAGAAAACCTACAACCGCAGGATATCGTGGCAATAGGCTGCCACGGTCAAACGGTCTGGCATGAACCACAAGG
CCCGGCTCCCCATACTTTGCAAATTGGTGATAACAATCAGATCGTTGCCCGTACAGGCATCACCGTTGTCGGGGATTTTC
GTCGCCGTGATATCGCGCTCGGTGGACAAGGCGCACCACTGGTGCCGGCGTTTCATCATGCACTGTTAGCACATCCTACC
GAACGACGGATGGTGCTAAATATTGGGGGTATTGCCAATCTGTCAATGCTTCTCCCCGGACAACCAGTACGGGGTTACGA
CACCGGTCCTGGTAACATGTTGATGGATGCCTGGATCTGGCGGCAGTGTGCCAAACCGTATGATAAAGATGCTCAGTGGG
CCTGTGAAGGGAATGTCGTGTTACCGTTGTTACAGCAAATGCTTAACGATCCCTACTTTGCCGCACCAGCACCAAAAAGT
ACCGGGCGTGAATACTTCAATTATGGCTGGCTGGAACGTCATCTACAGAAATTCCCAGGACTGCGGTCGCGGGACGTTCA
GGCGACACTGGCAGAACTTACTGCTGTGACTATCTCCGAGCAAGTCTTGTTGAGCGGAGGCTGCGATCGCCTGATGGTGT
GTGGCGGAGGAAGTCGCAATCCATTAGTAATGGCGCGTCTGGCTGGTTTACTGCCTGGCACAGAGGTGACCACAACAGAT
ACGGCAGGTATCAGTGGTGATGATATGGAGGCTTTAGCTTTTGCATGGCTTGCCTGGCGAACACTGGCTGGTCTGGCGGG
CAATTTACCGTCGGTCACTGGCGCCAGTGAGGCGACAGTGCTTGGCGCAATTTTTCCAGCTAATCCCCCGCGAACTCAGA
GTTAA

Upstream 100 bases:

>100_bases
ACCACAGGCTAAAACAGCTAAAAAAATAGCTGAAGCATGGCATTGACGAGGCGTTTGTGGTGGAGTGTGACAGATAAATT
ATGCTGCATAAGGAAGGCCT

Downstream 100 bases:

>100_bases
CTGAATTTTTCTTAGTCATACTGCCGTTACACTAGGAATGTTAGGGAGGGCGTTTTGCCCTCCGGACCAGGAAAGTCTTC
AGGATGCTGCTATGAAAAAA

Product: anhydro-N-acetylmuramic acid kinase

Products: NA

Alternate protein names: AnhMurNAc kinase

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MRSGRYIGVMSGTSLDGVDVVLAAIDENMVAQQASLSWPIPVELKQAVLDICQGQQLTLSQFGQLDTRLGILFADAVNGL
LAQENLQPQDIVAIGCHGQTVWHEPQGPAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPT
ERRMVLNIGGIANLSMLLPGQPVRGYDTGPGNMLMDAWIWRQCAKPYDKDAQWACEGNVVLPLLQQMLNDPYFAAPAPKS
TGREYFNYGWLERHLQKFPGLRSRDVQATLAELTAVTISEQVLLSGGCDRLMVCGGGSRNPLVMARLAGLLPGTEVTTTD
TAGISGDDMEALAFAWLAWRTLAGLAGNLPSVTGASEATVLGAIFPANPPRTQS

Sequences:

>Translated_374_residues
MRSGRYIGVMSGTSLDGVDVVLAAIDENMVAQQASLSWPIPVELKQAVLDICQGQQLTLSQFGQLDTRLGILFADAVNGL
LAQENLQPQDIVAIGCHGQTVWHEPQGPAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPT
ERRMVLNIGGIANLSMLLPGQPVRGYDTGPGNMLMDAWIWRQCAKPYDKDAQWACEGNVVLPLLQQMLNDPYFAAPAPKS
TGREYFNYGWLERHLQKFPGLRSRDVQATLAELTAVTISEQVLLSGGCDRLMVCGGGSRNPLVMARLAGLLPGTEVTTTD
TAGISGDDMEALAFAWLAWRTLAGLAGNLPSVTGASEATVLGAIFPANPPRTQS
>Mature_374_residues
MRSGRYIGVMSGTSLDGVDVVLAAIDENMVAQQASLSWPIPVELKQAVLDICQGQQLTLSQFGQLDTRLGILFADAVNGL
LAQENLQPQDIVAIGCHGQTVWHEPQGPAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPT
ERRMVLNIGGIANLSMLLPGQPVRGYDTGPGNMLMDAWIWRQCAKPYDKDAQWACEGNVVLPLLQQMLNDPYFAAPAPKS
TGREYFNYGWLERHLQKFPGLRSRDVQATLAELTAVTISEQVLLSGGCDRLMVCGGGSRNPLVMARLAGLLPGTEVTTTD
TAGISGDDMEALAFAWLAWRTLAGLAGNLPSVTGASEATVLGAIFPANPPRTQS

Specific function: Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived

COG id: COG2377

COG function: function code O; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anhydro-N-acetylmuramic acid kinase family

Homologues:

Organism=Escherichia coli, GI1787928, Length=369, Percent_Identity=88.0758807588076, Blast_Score=647, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANMK_ESCF3 (B7LQN0)

Other databases:

- EMBL:   CU928158
- RefSeq:   YP_002382555.1
- ProteinModelPortal:   B7LQN0
- EnsemblBacteria:   EBESCT00000122489
- GeneID:   7121791
- GenomeReviews:   CU928158_GR
- KEGG:   efe:EFER_1403
- GeneTree:   EBGT00050000010687
- HOGENOM:   HBG324434
- ProtClustDB:   PRK09585
- BioCyc:   EFER585054:EFER_1403-MONOMER
- HAMAP:   MF_01270
- InterPro:   IPR005338

Pfam domain/function: PF03702 UPF0075

EC number: NA

Molecular weight: Translated: 40046; Mature: 40046

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSGRYIGVMSGTSLDGVDVVLAAIDENMVAQQASLSWPIPVELKQAVLDICQGQQLTLS
CCCCCEEEEECCCCCCCHHHHEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEECHH
QFGQLDTRLGILFADAVNGLLAQENLQPQDIVAIGCHGQTVWHEPQGPAPHTLQIGDNNQ
HHCCHHHHHHEEEHHHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCCCCEEEECCCCE
IVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPTERRMVLNIGGIANLSMLLPG
EEEECCCEEEECCCCCEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCC
QPVRGYDTGPGNMLMDAWIWRQCAKPYDKDAQWACEGNVVLPLLQQMLNDPYFAAPAPKS
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHCCCEECCCCCCC
TGREYFNYGWLERHLQKFPGLRSRDVQATLAELTAVTISEQVLLSGGCDRLMVCGGGSRN
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
PLVMARLAGLLPGTEVTTTDTAGISGDDMEALAFAWLAWRTLAGLAGNLPSVTGASEATV
CHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
LGAIFPANPPRTQS
EEEEECCCCCCCCC
>Mature Secondary Structure
MRSGRYIGVMSGTSLDGVDVVLAAIDENMVAQQASLSWPIPVELKQAVLDICQGQQLTLS
CCCCCEEEEECCCCCCCHHHHEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEECHH
QFGQLDTRLGILFADAVNGLLAQENLQPQDIVAIGCHGQTVWHEPQGPAPHTLQIGDNNQ
HHCCHHHHHHEEEHHHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCCCCCEEEECCCCE
IVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPTERRMVLNIGGIANLSMLLPG
EEEECCCEEEECCCCCEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCEEEEECCC
QPVRGYDTGPGNMLMDAWIWRQCAKPYDKDAQWACEGNVVLPLLQQMLNDPYFAAPAPKS
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHCCCEECCCCCCC
TGREYFNYGWLERHLQKFPGLRSRDVQATLAELTAVTISEQVLLSGGCDRLMVCGGGSRN
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
PLVMARLAGLLPGTEVTTTDTAGISGDDMEALAFAWLAWRTLAGLAGNLPSVTGASEATV
CHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
LGAIFPANPPRTQS
EEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA