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The map label for this gene is znuA [H]

Identifier: 218548582

GI number: 218548582

Start: 1255834

End: 1256820

Strand: Direct

Name: znuA [H]

Synonym: EFER_1215

Alternate gene names: 218548582

Gene position: 1255834-1256820 (Clockwise)

Preceding gene: 218548579

Following gene: 218548583

Centisome position: 27.37

GC content: 46.2

Gene sequence:

>987_bases
ATGAAATGTTATAATATCACATTTCTTCTATTCAGTACGATGATTGGTCGCATTATGTTACATAAAAATACGCTTCTTTT
CGCGGCATTATCCGCCGCCTTATGGGGGAGTGCAACACAGGCGGCAAATGCCGCTGTAGTAGCATCTCTCAAGCCAATCG
GCTTTATTGCAGCAGCTATTGCTGATGGGGTTACATATACAGAAATATTATTACCAGATGGTGCATCTGAGCATGATTAT
TCACTGCGTCCATCAGACGTTAAACGCTTACAGAACGCGGACTTAGTCATTTGGGTTGGTCCGGAAATGGAAGCATTCAT
GGAAAAAGCCGTCAACAAAATTCCGCCCTCGAAACAAGTTACAATTGCGCAACTTCCTGACGTACAACCATTGCTATTGA
AAGGGAATGATGAAGACGAGCACGATCATGCCGGGGGTGAAAACAGTGACGAACATCACCATCATGGCGATTACAACATG
CACTTATGGCTTTCTCCAGAGATAGCGCGGGCCTCAGCGGTTGCAATCCATAAAAAATTAGTGGAACTTATGCCGCAAAG
TCGAGCCAAACTTGACGCCAACCTGAAGGATTTTGAGGCACAATTAGCCACAACCGACAAACAGGTGGGTAACGAGCTCG
CACCGCTCAAGGGTAAAGGTTATTTCGTTTTCCACGATGCCTGGGGTTATTACGAAAAACATTTCGGACTGACACCGCTC
GGTCATTTTACCGTTAATCCTGAGATACAACCTGGTGCGCAGCGTTTACATGAGATTAGAACACAGTTGGTTGAGCAAAA
AGCAACTTGCGTTTTTGCTGAGCCACAGTTCAGGCCAGCGGTCGTAGAAAGCGTTGCGAGAGGGACATCCGTTCGAATGG
GGACGTTGGATCCCCTCGGTACGAATATCAAACTGGGCAAAACGAGCTATTCAGCATTTTTGACCCAGGTCGCTAATCAA
TATGCGAGCTGCCTGAAAGGAGAATAA

Upstream 100 bases:

>100_bases
CAAGCGACACGTCAGACAGCACGCGGCGTTGGCCAAAGGAGACTGAAACCTTATCCAGTGAAACCAGGGTTGTCATGTTA
ATTTTAGTCTTGCAGAAGTC

Downstream 100 bases:

>100_bases
CGAGGAAGTGATTACGTGCAACAGATAGCCCGCTCTGTCGCCCTGGCATTTAACAATTTGCCGCGACCTCACCGCGTTAT
GCTGGGGTCGCTTACCGTTC

Product: high-affinity zinc transporter periplasmic component

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKCYNITFLLFSTMIGRIMLHKNTLLFAALSAALWGSATQAANAAVVASLKPIGFIAAAIADGVTYTEILLPDGASEHDY
SLRPSDVKRLQNADLVIWVGPEMEAFMEKAVNKIPPSKQVTIAQLPDVQPLLLKGNDEDEHDHAGGENSDEHHHHGDYNM
HLWLSPEIARASAVAIHKKLVELMPQSRAKLDANLKDFEAQLATTDKQVGNELAPLKGKGYFVFHDAWGYYEKHFGLTPL
GHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMGTLDPLGTNIKLGKTSYSAFLTQVANQ
YASCLKGE

Sequences:

>Translated_328_residues
MKCYNITFLLFSTMIGRIMLHKNTLLFAALSAALWGSATQAANAAVVASLKPIGFIAAAIADGVTYTEILLPDGASEHDY
SLRPSDVKRLQNADLVIWVGPEMEAFMEKAVNKIPPSKQVTIAQLPDVQPLLLKGNDEDEHDHAGGENSDEHHHHGDYNM
HLWLSPEIARASAVAIHKKLVELMPQSRAKLDANLKDFEAQLATTDKQVGNELAPLKGKGYFVFHDAWGYYEKHFGLTPL
GHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMGTLDPLGTNIKLGKTSYSAFLTQVANQ
YASCLKGE
>Mature_328_residues
MKCYNITFLLFSTMIGRIMLHKNTLLFAALSAALWGSATQAANAAVVASLKPIGFIAAAIADGVTYTEILLPDGASEHDY
SLRPSDVKRLQNADLVIWVGPEMEAFMEKAVNKIPPSKQVTIAQLPDVQPLLLKGNDEDEHDHAGGENSDEHHHHGDYNM
HLWLSPEIARASAVAIHKKLVELMPQSRAKLDANLKDFEAQLATTDKQVGNELAPLKGKGYFVFHDAWGYYEKHFGLTPL
GHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMGTLDPLGTNIKLGKTSYSAFLTQVANQ
YASCLKGE

Specific function: Involved in the high-affinity zinc uptake transport system [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=310, Percent_Identity=86.7741935483871, Blast_Score=532, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 36026; Mature: 36026

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCYNITFLLFSTMIGRIMLHKNTLLFAALSAALWGSATQAANAAVVASLKPIGFIAAAI
CCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHCCEEEEEECCHHHHHHHHH
ADGVTYTEILLPDGASEHDYSLRPSDVKRLQNADLVIWVGPEMEAFMEKAVNKIPPSKQV
HCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCE
TIAQLPDVQPLLLKGNDEDEHDHAGGENSDEHHHHGDYNMHLWLSPEIARASAVAIHKKL
EEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHH
VELMPQSRAKLDANLKDFEAQLATTDKQVGNELAPLKGKGYFVFHDAWGYYEKHFGLTPL
HHHCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHCCCCCC
GHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMGTLDPLG
CCEEECCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCEEECCCCCCC
TNIKLGKTSYSAFLTQVANQYASCLKGE
CCEEECCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKCYNITFLLFSTMIGRIMLHKNTLLFAALSAALWGSATQAANAAVVASLKPIGFIAAAI
CCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHCCEEEEEECCHHHHHHHHH
ADGVTYTEILLPDGASEHDYSLRPSDVKRLQNADLVIWVGPEMEAFMEKAVNKIPPSKQV
HCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCE
TIAQLPDVQPLLLKGNDEDEHDHAGGENSDEHHHHGDYNMHLWLSPEIARASAVAIHKKL
EEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHH
VELMPQSRAKLDANLKDFEAQLATTDKQVGNELAPLKGKGYFVFHDAWGYYEKHFGLTPL
HHHCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHCCCCCC
GHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMGTLDPLG
CCEEECCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCEEECCCCCCC
TNIKLGKTSYSAFLTQVANQYASCLKGE
CCEEECCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 9600841; 9680209 [H]