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The map label for this gene is flhA [H]

Identifier: 218548563

GI number: 218548563

Start: 1238139

End: 1240217

Strand: Direct

Name: flhA [H]

Synonym: EFER_1195

Alternate gene names: 218548563

Gene position: 1238139-1240217 (Clockwise)

Preceding gene: 218548562

Following gene: 218548564

Centisome position: 26.98

GC content: 52.04

Gene sequence:

>2079_bases
ATGACTAATCTGGCCTCCGTGCTGCGCTTGCCCGGCAACCTGAAATCAACACAATGGCAGATCCTCGCCGGACCCATCCT
CATCTTGCTGATTTTGTCGATGATGGTGCTGCCATTGCCAGCGTTTATCCTCGACTTGTTGTTCACCTTTAATATCGCGC
TATCGATAATGGTGCTGCTGGTGGCGATGTTTACCCAGCGCACGCTCGACTTTGCCGCGTTTCCGACAATTCTGTTGTTC
ACCACATTGCTAAGACTGGCACTTAACGTCGCTTCAACACGTATCATTTTAATGGAAGGGCATACAGGCGCAGCTGCGGC
AGGGAAAGTGGTGGAAGCGTTCGGTCACTTTCTGGTTGGTGGCAATTTCGCCATTGGTATCGTGGTGTTTATCATTCTGG
TCATCATCAACTTTATGGTTATCACCAAAGGGGCGGGGCGTATTGCCGAAGTAGGTGCGCGTTTTGTTCTTGATGGTATG
CCAGGAAAACAGATGGCGATTGATGCTGATCTTAATGCCGGGTTGATCGGTGAAGATGAAGCGAAAAAACGCCGCGCGGA
AGTGACTCAGGAAGCGGATTTTTACGGTTCGATGGATGGTGCGAGTAAGTTCGTACGTGGTGATGCCATCGCCGGGATCT
TAATCATGGTCATCAACGTGATAGGTGGTTTATTGGTTGGGGTGCTGCAACATGGAATGAGTATGGGGCACGCCGCAGAA
AGCTACACACTGCTGACTATCGGTGATGGTCTGGTCGCACAAATTCCGGCTCTGGTGATCTCCACGGCGGCAGGGGTGAT
TGTTACTCGTGTCAGCACCGATCAGGATGTTGGCGAACAGATGGTCAAACAGCTGTTCAGTAACCCTCGGGTGATGTTGC
TCTGCGCAGCCGTTCTTGGCTTGCTCGGCCTGGTGCCAGGAATGCCGAATCTGGTGTTTTTGCTGTTTACTGCCGGGCTT
CTGGCACTGGCATGGTGGATTCGTGGTCAGGAACAAAAGGCACCTGCTGAACCACAACCGATAAAAATGCCGGAAAATAA
TTCAGTAATGGAAGCGACATGGAATGACGTGCAACTGGAAGATTCGCTCGGAATGGAAGTGGGATACCGTCTGATCCCGA
TGGTGGATATGCAACAGGATGGCGAGCTATTGGGGCGCATTCGTAGTATCCGCAAGAAATTCGCTCAGGATATGGGCTTT
CTGCCACCGGTAGTGCACATTCGCGACAATATGGATTTACAACCGGCACGGTATCGCATTTTGATGAAAGGGGTAGAAAT
TGGCAGTGGCGATGCTTATCCGGGGCGCTGGCTGGCCATTAACCCTGGGACAGCGGCAGGTACGCTGCCAGGCGAACAAA
CCGTTGATCCGGCATTTGGTTTAAGTGCTATCTGGATTGAAAGTGCACTGAAAGAACAAGCGCAGATTCAGGGATATACG
GTAGTCGAAGCCAGCACTGTAGTGGCTACTCATCTTAACCATCTGCTTGGGTTATATGCTGCGGAACTGTTTGGTCGCCA
GGAGGCGCAACAGTTGCTGGACCGCGTTACGCAGGAAATGCCGAAGTTGACGGAAGATCTGGTTCCTGGCGTTATCACGC
TCACCACACTCCACAAAGTGTTGCAAAATCTGCTGGATGAGAAAGTACCGATTCGTGATATGCGTACTATCCTCGAAACA
CTGGCTGAACATGCTCCCGTTCAGAGCGATCCTCACGAGTTAACTGCCGTTGTGCGTGTGGCGCTGGGGCGAGCGATTAC
TCAACGCTGGTTTCCTGGTAATAATGAAGTGCAGGTTATCGGACTTGATGTTGCGCTTGAACGTCTGCTATTGCAGGCTT
TACAGGGTGGTGGCGGACTGGAGCCTGGGTTGGCTGATCGTTTACTGGCGCAAACTCAGGAGGCGTTGTCTCGCCAGGAA
ACACTTGGCGCACCGCCTGTACTGCTGGTAAATCATGCGCTACGTCCGCTGCTCTCTCGCTTTTTACGCCGTAGCCTGCC
ACAACTGGTGGTGCTGTCGAATCTGGAACTTGCGGATAATCGACAGATCCGCATGACGGCAACGATTGGCGGGAAATAA

Upstream 100 bases:

>100_bases
CAATTAAAGCGTTGGCGTATTGCCGGTGGACAACGCCCGGTAAAACCTGCAAACCTCCCGGTGCCAGAGGCACTGGATTT
TATCAACGAGAAAACGACCG

Downstream 100 bases:

>100_bases
TGCGTAAGTTACTGGCAATATTGTTATTTCCACTGGTTGCCAAGGCTGCTGGCGAAGGAATGTGGCAGGCCAGCAGCTTT
GGCATTACGTTACATCATCG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MTNLASVLRLPGNLKSTQWQILAGPILILLILSMMVLPLPAFILDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLF
TTLLRLALNVASTRIILMEGHTGAAAAGKVVEAFGHFLVGGNFAIGIVVFIILVIINFMVITKGAGRIAEVGARFVLDGM
PGKQMAIDADLNAGLIGEDEAKKRRAEVTQEADFYGSMDGASKFVRGDAIAGILIMVINVIGGLLVGVLQHGMSMGHAAE
SYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGEQMVKQLFSNPRVMLLCAAVLGLLGLVPGMPNLVFLLFTAGL
LALAWWIRGQEQKAPAEPQPIKMPENNSVMEATWNDVQLEDSLGMEVGYRLIPMVDMQQDGELLGRIRSIRKKFAQDMGF
LPPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLPGEQTVDPAFGLSAIWIESALKEQAQIQGYT
VVEASTVVATHLNHLLGLYAAELFGRQEAQQLLDRVTQEMPKLTEDLVPGVITLTTLHKVLQNLLDEKVPIRDMRTILET
LAEHAPVQSDPHELTAVVRVALGRAITQRWFPGNNEVQVIGLDVALERLLLQALQGGGGLEPGLADRLLAQTQEALSRQE
TLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELADNRQIRMTATIGGK

Sequences:

>Translated_692_residues
MTNLASVLRLPGNLKSTQWQILAGPILILLILSMMVLPLPAFILDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLF
TTLLRLALNVASTRIILMEGHTGAAAAGKVVEAFGHFLVGGNFAIGIVVFIILVIINFMVITKGAGRIAEVGARFVLDGM
PGKQMAIDADLNAGLIGEDEAKKRRAEVTQEADFYGSMDGASKFVRGDAIAGILIMVINVIGGLLVGVLQHGMSMGHAAE
SYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGEQMVKQLFSNPRVMLLCAAVLGLLGLVPGMPNLVFLLFTAGL
LALAWWIRGQEQKAPAEPQPIKMPENNSVMEATWNDVQLEDSLGMEVGYRLIPMVDMQQDGELLGRIRSIRKKFAQDMGF
LPPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLPGEQTVDPAFGLSAIWIESALKEQAQIQGYT
VVEASTVVATHLNHLLGLYAAELFGRQEAQQLLDRVTQEMPKLTEDLVPGVITLTTLHKVLQNLLDEKVPIRDMRTILET
LAEHAPVQSDPHELTAVVRVALGRAITQRWFPGNNEVQVIGLDVALERLLLQALQGGGGLEPGLADRLLAQTQEALSRQE
TLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELADNRQIRMTATIGGK
>Mature_691_residues
TNLASVLRLPGNLKSTQWQILAGPILILLILSMMVLPLPAFILDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLFT
TLLRLALNVASTRIILMEGHTGAAAAGKVVEAFGHFLVGGNFAIGIVVFIILVIINFMVITKGAGRIAEVGARFVLDGMP
GKQMAIDADLNAGLIGEDEAKKRRAEVTQEADFYGSMDGASKFVRGDAIAGILIMVINVIGGLLVGVLQHGMSMGHAAES
YTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGEQMVKQLFSNPRVMLLCAAVLGLLGLVPGMPNLVFLLFTAGLL
ALAWWIRGQEQKAPAEPQPIKMPENNSVMEATWNDVQLEDSLGMEVGYRLIPMVDMQQDGELLGRIRSIRKKFAQDMGFL
PPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLPGEQTVDPAFGLSAIWIESALKEQAQIQGYTV
VEASTVVATHLNHLLGLYAAELFGRQEAQQLLDRVTQEMPKLTEDLVPGVITLTTLHKVLQNLLDEKVPIRDMRTILETL
AEHAPVQSDPHELTAVVRVALGRAITQRWFPGNNEVQVIGLDVALERLLLQALQGGGGLEPGLADRLLAQTQEALSRQET
LGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELADNRQIRMTATIGGK

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=692, Percent_Identity=94.364161849711, Blast_Score=1289, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74887; Mature: 74756

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLASVLRLPGNLKSTQWQILAGPILILLILSMMVLPLPAFILDLLFTFNIALSIMVLL
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAMFTQRTLDFAAFPTILLFTTLLRLALNVASTRIILMEGHTGAAAAGKVVEAFGHFLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHC
GNFAIGIVVFIILVIINFMVITKGAGRIAEVGARFVLDGMPGKQMAIDADLNAGLIGEDE
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHEECCCCCCCEEEECCCCCCCCCCHH
AKKRRAEVTQEADFYGSMDGASKFVRGDAIAGILIMVINVIGGLLVGVLQHGMSMGHAAE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGEQMVKQLFSNPRVMLLCAAVLG
CEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LLGLVPGMPNLVFLLFTAGLLALAWWIRGQEQKAPAEPQPIKMPENNSVMEATWNDVQLE
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEC
DSLGMEVGYRLIPMVDMQQDGELLGRIRSIRKKFAQDMGFLPPVVHIRDNMDLQPARYRI
HHCCHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHH
LMKGVEIGSGDAYPGRWLAINPGTAAGTLPGEQTVDPAFGLSAIWIESALKEQAQIQGYT
HHHCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHCCEE
VVEASTVVATHLNHLLGLYAAELFGRQEAQQLLDRVTQEMPKLTEDLVPGVITLTTLHKV
EEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LQNLLDEKVPIRDMRTILETLAEHAPVQSDPHELTAVVRVALGRAITQRWFPGNNEVQVI
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
GLDVALERLLLQALQGGGGLEPGLADRLLAQTQEALSRQETLGAPPVLLVNHALRPLLSR
EHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FLRRSLPQLVVLSNLELADNRQIRMTATIGGK
HHHHCCCCEEHHCCCEECCCCEEEEEEECCCC
>Mature Secondary Structure 
TNLASVLRLPGNLKSTQWQILAGPILILLILSMMVLPLPAFILDLLFTFNIALSIMVLL
CCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAMFTQRTLDFAAFPTILLFTTLLRLALNVASTRIILMEGHTGAAAAGKVVEAFGHFLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHC
GNFAIGIVVFIILVIINFMVITKGAGRIAEVGARFVLDGMPGKQMAIDADLNAGLIGEDE
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHEECCCCCCCEEEECCCCCCCCCCHH
AKKRRAEVTQEADFYGSMDGASKFVRGDAIAGILIMVINVIGGLLVGVLQHGMSMGHAAE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGEQMVKQLFSNPRVMLLCAAVLG
CEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LLGLVPGMPNLVFLLFTAGLLALAWWIRGQEQKAPAEPQPIKMPENNSVMEATWNDVQLE
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEC
DSLGMEVGYRLIPMVDMQQDGELLGRIRSIRKKFAQDMGFLPPVVHIRDNMDLQPARYRI
HHCCHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHH
LMKGVEIGSGDAYPGRWLAINPGTAAGTLPGEQTVDPAFGLSAIWIESALKEQAQIQGYT
HHHCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHCHHHHHHHHHHHHHHHHCCEE
VVEASTVVATHLNHLLGLYAAELFGRQEAQQLLDRVTQEMPKLTEDLVPGVITLTTLHKV
EEEHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LQNLLDEKVPIRDMRTILETLAEHAPVQSDPHELTAVVRVALGRAITQRWFPGNNEVQVI
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
GLDVALERLLLQALQGGGGLEPGLADRLLAQTQEALSRQETLGAPPVLLVNHALRPLLSR
EHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
FLRRSLPQLVVLSNLELADNRQIRMTATIGGK
HHHHCCCCEEHHCCCEECCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]