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The map label for this gene is flhB [H]

Identifier: 218548562

GI number: 218548562

Start: 1236998

End: 1238146

Strand: Direct

Name: flhB [H]

Synonym: EFER_1194

Alternate gene names: 218548562

Gene position: 1236998-1238146 (Clockwise)

Preceding gene: 218548561

Following gene: 218548563

Centisome position: 26.96

GC content: 51.26

Gene sequence:

>1149_bases
GTGTCTGACGAGAGCGACGACAAAACAGAAGCCCCCACACCTCACCGACTGGAAAAAGCCAGGGAAGAAGGGCAAATCCC
GCGTTCCCGTGAACTCACGTCGATGCTGATCTTACTGGTCGGTGTTTGTGTCATTTGGTTTGGCGGCGAATCACTGGCAC
GGCAGCTTGCTGCGATGTTATCGGCAGGTTTGCACTTTGACCATCATCTGATTAACGATCCAAATCTGATCCTTGGGCAA
ATTATTCTGCTGATTAAACAAGCGATGATGGCGCTATTGCCGCTGATTACTGGCGTCGTGCTGGTGGCGTTGATCTCTCC
GGTTTTGCTGGGAGGATTAATTTTTAGTGGCAAATCGTTACAACCGAAATTCTCTAAACTGAATCCGTTACCAGGAATTA
AACGGATGTTTTCTGCCCAGACCGGAGCAGAGTTATTAAAAGCGATCCTCAAATCAACATTGGTGGGGTGCGTAGCCGGG
TTTTACTTATGGCATAAGTGGCCAGAGATGATGCGCCTGATGGCGCAATCGCCAATTACCGCTATGGGTAATGCGTTGGA
TCTGGTTGGCCTGTGCGCACTGCTGGTGGTGCTGGGTGTCATTCCGATGGTCGGTTTTGACGTTTTTTATCAAATCTTCA
GCCATCTTAAGAAACTTCGCATGTCACGCCAGGATATTCGCGATGAGTTTAAACAAAGCGAAGGCGACCCACACGTTAAA
GGCCGTATCCGTCAAATGCAGCGGGCCGCTGCCCGACGACGAATGATGAATGATGTGCCCCAGGCTGATGTTATCGTCAA
TAACCCGACGCACTATTCTGTGGCACTGCAATACGACGAAAACAAAATGAGCGCACCAAAAGTGATTGCCAAAGGGGCAG
GGCTGGTGGCGCTGCGTATTCGGGAAATTGCGGCCGAACACCATATTCCAACACTGGAAGCGCCACCTCTGGCGCGTGCG
CTATATCGCCATGCCGAAATTGGCCAGCAAATCCCCGGTCAACTGTATGCTGCCGTAGCAGAGGTGCTGGCGTGGGTATG
GCAATTAAAGCGTTGGCGTATTGCCGGTGGACAACGCCCGGTAAAACCTGCAAACCTCCCGGTGCCAGAGGCACTGGATT
TTATCAACGAGAAAACGACCGATGACTAA

Upstream 100 bases:

>100_bases
GTAAAAGTCGATAAACCCACCTATTTCACCTCTTACTCTTGCCATTGACTACGCGCAGGTCTGGCATCATTGGCATATCT
TTATTACCAGGATCTGCCGC

Downstream 100 bases:

>100_bases
TCTGGCCTCCGTGCTGCGCTTGCCCGGCAACCTGAAATCAACACAATGGCAGATCCTCGCCGGACCCATCCTCATCTTGC
TGATTTTGTCGATGATGGTG

Product: flagellar biosynthesis protein FlhB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSDESDDKTEAPTPHRLEKAREEGQIPRSRELTSMLILLVGVCVIWFGGESLARQLAAMLSAGLHFDHHLINDPNLILGQ
IILLIKQAMMALLPLITGVVLVALISPVLLGGLIFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAILKSTLVGCVAG
FYLWHKWPEMMRLMAQSPITAMGNALDLVGLCALLVVLGVIPMVGFDVFYQIFSHLKKLRMSRQDIRDEFKQSEGDPHVK
GRIRQMQRAAARRRMMNDVPQADVIVNNPTHYSVALQYDENKMSAPKVIAKGAGLVALRIREIAAEHHIPTLEAPPLARA
LYRHAEIGQQIPGQLYAAVAEVLAWVWQLKRWRIAGGQRPVKPANLPVPEALDFINEKTTDD

Sequences:

>Translated_382_residues
MSDESDDKTEAPTPHRLEKAREEGQIPRSRELTSMLILLVGVCVIWFGGESLARQLAAMLSAGLHFDHHLINDPNLILGQ
IILLIKQAMMALLPLITGVVLVALISPVLLGGLIFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAILKSTLVGCVAG
FYLWHKWPEMMRLMAQSPITAMGNALDLVGLCALLVVLGVIPMVGFDVFYQIFSHLKKLRMSRQDIRDEFKQSEGDPHVK
GRIRQMQRAAARRRMMNDVPQADVIVNNPTHYSVALQYDENKMSAPKVIAKGAGLVALRIREIAAEHHIPTLEAPPLARA
LYRHAEIGQQIPGQLYAAVAEVLAWVWQLKRWRIAGGQRPVKPANLPVPEALDFINEKTTDD
>Mature_381_residues
SDESDDKTEAPTPHRLEKAREEGQIPRSRELTSMLILLVGVCVIWFGGESLARQLAAMLSAGLHFDHHLINDPNLILGQI
ILLIKQAMMALLPLITGVVLVALISPVLLGGLIFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAILKSTLVGCVAGF
YLWHKWPEMMRLMAQSPITAMGNALDLVGLCALLVVLGVIPMVGFDVFYQIFSHLKKLRMSRQDIRDEFKQSEGDPHVKG
RIRQMQRAAARRRMMNDVPQADVIVNNPTHYSVALQYDENKMSAPKVIAKGAGLVALRIREIAAEHHIPTLEAPPLARAL
YRHAEIGQQIPGQLYAAVAEVLAWVWQLKRWRIAGGQRPVKPANLPVPEALDFINEKTTDD

Specific function: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1377

COG function: function code NU; Flagellar biosynthesis pathway, component FlhB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III secretion exporter family [H]

Homologues:

Organism=Escherichia coli, GI1788188, Length=382, Percent_Identity=90.0523560209424, Blast_Score=662, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006136
- InterPro:   IPR006135 [H]

Pfam domain/function: PF01312 Bac_export_2 [H]

EC number: NA

Molecular weight: Translated: 42333; Mature: 42201

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDESDDKTEAPTPHRLEKAREEGQIPRSRELTSMLILLVGVCVIWFGGESLARQLAAML
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
SAGLHFDHHLINDPNLILGQIILLIKQAMMALLPLITGVVLVALISPVLLGGLIFSGKSL
HHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QPKFSKLNPLPGIKRMFSAQTGAELLKAILKSTLVGCVAGFYLWHKWPEMMRLMAQSPIT
CCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AMGNALDLVGLCALLVVLGVIPMVGFDVFYQIFSHLKKLRMSRQDIRDEFKQSEGDPHVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
GRIRQMQRAAARRRMMNDVPQADVIVNNPTHYSVALQYDENKMSAPKVIAKGAGLVALRI
HHHHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCCCHHHHHCCCCHHHHHH
REIAAEHHIPTLEAPPLARALYRHAEIGQQIPGQLYAAVAEVLAWVWQLKRWRIAGGQRP
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VKPANLPVPEALDFINEKTTDD
CCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8002587; 11677609; 3298217 [H]