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The map label for this gene is pncB [H]

Identifier: 218548447

GI number: 218548447

Start: 1116454

End: 1117656

Strand: Reverse

Name: pncB [H]

Synonym: EFER_1075

Alternate gene names: 218548447

Gene position: 1117656-1116454 (Counterclockwise)

Preceding gene: 218548449

Following gene: 218548446

Centisome position: 24.36

GC content: 48.38

Gene sequence:

>1203_bases
ATGACACAATTCGCTTCTCCTGTTCTGCACTCGTTGCTGGATACAGATGCTTATAAGTTGCATATGCAGCAAGCTGTTTT
TCATCACTATCACGATGTGCATGTAGCCGCTGAATTTCGTTGCCGTGGTGACGACCTTTTGGGGATATATGCTGATGCCA
TCCGCGAGCAGGTGCATGCAATGCAACATCTGCGTCTTCAGGAGGAGGAGTTCCAGTGGCTGACCGGTCTGCCCTTCTTC
AAGCCTGATTACCTGAACTGGCTGCGTGATTTTCGCTATAACCCGGAGCAAGTTTCCGTTACTAACGATAACGGTAAACT
TAATATTCGCCTTACCGGGCCGTGGCTGGAAGTAATCATGTGGGAAGTTCCGTTACTGGCAGTGATCAGTGAACTGGTGC
ATCACTATCGTTCCCCCGAGGCTAGTGTACAGCTGGCGATGAATACCCTTGAGCAAAAACTGGCTGATTTCACCACATTA
ACTGCCGGGCTCGATATGTCGCGCTTCCATTTGATGGATTTCGGTACTCGTCGGCGTTTTTCCCGAGACGTACAAGAAGC
CATTGTTAAGCGCTTACAGCAAGAATCCTGGTTTGTCGGTACCAGTAATTACGATCTGGCACGTCGTTTGTCGCTCACAC
CGATGGGTACCCAGGCGCATGAGTGGTTTCAGGCACATCAACAAATTAGCCCAGATTTAGCGACCAGTCAGCGAGCTGCA
CTTGCTGCCTGGCTGGAAGAGTATCCCGATCAACTTGGCATTGCATTAACCGACTGCATCACTATGGATGCCTTCCTGCG
TGATTTCGGTGTCGAGTTCGCCAGTCGTTATCAGGGATTACGCCATGACTCTGGCGATCCGGTTGAATGGGGTGAAAAAG
CCATTGCCCATTATCTGAAGCTGGGTATCGATCCACAAAGTAAGGTGTTAGTGTTTTCCGATAATCTCGATTTAACGAAG
GCTATTGAGCTTTATCGGCACTTCTCTTCGCGAATCAAATTGAGCTTTGGTATTGGCACACGACTGACCTGTGATATTCC
TCAGGTTAAACCACTCAATATTGTGATTAAGCTGGTGGAATGTAATGGTAAGCCGGTGGCTAAGCTTTCTGATAGCCCAG
GTAAAACCATTTGCCATGATAAAGCCTTTGTGCGGGCATTGCGCAAAGCCTTCGATCTTCCCCAAATCAAAAAAGCCAGT
TAA

Upstream 100 bases:

>100_bases
GATCGGGGTTCAATAAATCGCTAAACAAGGTATACTCCAGCGGTTTTCGAAGATGTTTATTGTACTAAACGCTCCCGCGA
GAGGATGCTACTGCGAACCT

Downstream 100 bases:

>100_bases
TTTAGAGGGAGTCGTAAAGGCTCCCTTTTTGCCTTTTATTCTGAAATCTTTCACTCAGCCTGCGAATTCTGCTTGTCTGA
TTGCAGATGCCAGGTAACAT

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTQFASPVLHSLLDTDAYKLHMQQAVFHHYHDVHVAAEFRCRGDDLLGIYADAIREQVHAMQHLRLQEEEFQWLTGLPFF
KPDYLNWLRDFRYNPEQVSVTNDNGKLNIRLTGPWLEVIMWEVPLLAVISELVHHYRSPEASVQLAMNTLEQKLADFTTL
TAGLDMSRFHLMDFGTRRRFSRDVQEAIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLATSQRAA
LAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYLKLGIDPQSKVLVFSDNLDLTK
AIELYRHFSSRIKLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQIKKAS

Sequences:

>Translated_400_residues
MTQFASPVLHSLLDTDAYKLHMQQAVFHHYHDVHVAAEFRCRGDDLLGIYADAIREQVHAMQHLRLQEEEFQWLTGLPFF
KPDYLNWLRDFRYNPEQVSVTNDNGKLNIRLTGPWLEVIMWEVPLLAVISELVHHYRSPEASVQLAMNTLEQKLADFTTL
TAGLDMSRFHLMDFGTRRRFSRDVQEAIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLATSQRAA
LAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYLKLGIDPQSKVLVFSDNLDLTK
AIELYRHFSSRIKLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQIKKAS
>Mature_399_residues
TQFASPVLHSLLDTDAYKLHMQQAVFHHYHDVHVAAEFRCRGDDLLGIYADAIREQVHAMQHLRLQEEEFQWLTGLPFFK
PDYLNWLRDFRYNPEQVSVTNDNGKLNIRLTGPWLEVIMWEVPLLAVISELVHHYRSPEASVQLAMNTLEQKLADFTTLT
AGLDMSRFHLMDFGTRRRFSRDVQEAIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLATSQRAAL
AAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYLKLGIDPQSKVLVFSDNLDLTKA
IELYRHFSSRIKLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQIKKAS

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=400, Percent_Identity=90.5, Blast_Score=769, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6324783, Length=419, Percent_Identity=34.3675417661098, Blast_Score=210, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45850; Mature: 45719

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQFASPVLHSLLDTDAYKLHMQQAVFHHYHDVHVAAEFRCRGDDLLGIYADAIREQVHA
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHH
MQHLRLQEEEFQWLTGLPFFKPDYLNWLRDFRYNPEQVSVTNDNGKLNIRLTGPWLEVIM
HHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECHHHHHHH
WEVPLLAVISELVHHYRSPEASVQLAMNTLEQKLADFTTLTAGLDMSRFHLMDFGTRRRF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHH
SRDVQEAIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLATSQRAA
HHHHHHHHHHHHHHCCEEECCCCCCHHHHEECCCCCCHHHHHHHHHHHCCCCHHHHHHHH
LAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYLK
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
LGIDPQSKVLVFSDNLDLTKAIELYRHFSSRIKLSFGIGTRLTCDIPQVKPLNIVIKLVE
HCCCCCCCEEEEECCCCHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCEEEEEEEE
CNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQIKKAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TQFASPVLHSLLDTDAYKLHMQQAVFHHYHDVHVAAEFRCRGDDLLGIYADAIREQVHA
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHHHHH
MQHLRLQEEEFQWLTGLPFFKPDYLNWLRDFRYNPEQVSVTNDNGKLNIRLTGPWLEVIM
HHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECHHHHHHH
WEVPLLAVISELVHHYRSPEASVQLAMNTLEQKLADFTTLTAGLDMSRFHLMDFGTRRRF
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHH
SRDVQEAIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLATSQRAA
HHHHHHHHHHHHHHCCEEECCCCCCHHHHEECCCCCCHHHHHHHHHHHCCCCHHHHHHHH
LAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYLK
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
LGIDPQSKVLVFSDNLDLTKAIELYRHFSSRIKLSFGIGTRLTCDIPQVKPLNIVIKLVE
HCCCCCCCEEEEECCCCHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCCCCEEEEEEEE
CNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQIKKAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA