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The map label for this gene is atoA [H]

Identifier: 218548318

GI number: 218548318

Start: 960632

End: 961282

Strand: Reverse

Name: atoA [H]

Synonym: EFER_0937

Alternate gene names: 218548318

Gene position: 961282-960632 (Counterclockwise)

Preceding gene: 218548319

Following gene: 218548317

Centisome position: 20.95

GC content: 52.84

Gene sequence:

>651_bases
ATGGACGCGAAACAACGTATTGCGCGCCGCGTGGCGCAGGAACTTTGTGATGGTGACATCGTTAACTTAGGGATCGGTTT
ACCCACAATGGTCGCCAACTATTTGCCGGAGGGTATTCATATCACTCTGCAATCGGAAAACGGCTTCCTCGGTTTAGGCC
CGGTCACGAAAGCGCATCCAGATTTGGTTAACGCGGGCGGACAACCGTGTGGCGTTTTACCCGGCGCAGCGATGTTCGAC
AGCGCCATGTCATTTGCGCTGATTCGTGGTGGTCATATTGATGCCTGTGTACTCGGTGGCTTACAGGTCGATGAACAAGG
CAATCTCGCCAACTGGGTCGTGCCAGGAAAAATGGTGCCTGGTATGGGTGGTGCGATGGATCTGGTGACCGGGTCGCGCA
AAGTGATCATTGCCATGGAACATTGCGCCAAAGATGGTTCAGCAAAAATTTTACGTCAATGCACCATGCCGCTAACCGCG
CTTCATGCAGTTCATATGCTGGTGACAGAACTGGCGGTGTTCCGCTTTATCGATGGCAAGATGTGGCTCACTGAAATTGC
CGAAGGTTGTGATTTAGAAACTGTGCGTGCCAAAACTGAAGCACAGTTCGCCGTCGCTGATGATCTTCTGCTCCCACAGG
GGGCGCTATGA

Upstream 100 bases:

>100_bases
AACCCGACGAACTGGTCGACACGGGAGAATTGCAACCTGACCACATAGTCACCCCCGGTGCCGTTATCGACCACATCATC
ATCCCACAGGAGAGTAAATA

Downstream 100 bases:

>100_bases
TCGGTCGCATATCGCGTTTTATGACGCGCTTTGTCAGTCGCTGGCTTCCCGATCCTCTGATCTTCGCCATGCTACTGACA
TTAATCACCTTTGCCGTAGC

Product: acetyl-CoA:acetoacetyl-CoA transferase subunit beta

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit beta [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MDAKQRIARRVAQELCDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTKAHPDLVNAGGQPCGVLPGAAMFD
SAMSFALIRGGHIDACVLGGLQVDEQGNLANWVVPGKMVPGMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRQCTMPLTA
LHAVHMLVTELAVFRFIDGKMWLTEIAEGCDLETVRAKTEAQFAVADDLLLPQGAL

Sequences:

>Translated_216_residues
MDAKQRIARRVAQELCDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTKAHPDLVNAGGQPCGVLPGAAMFD
SAMSFALIRGGHIDACVLGGLQVDEQGNLANWVVPGKMVPGMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRQCTMPLTA
LHAVHMLVTELAVFRFIDGKMWLTEIAEGCDLETVRAKTEAQFAVADDLLLPQGAL
>Mature_216_residues
MDAKQRIARRVAQELCDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTKAHPDLVNAGGQPCGVLPGAAMFD
SAMSFALIRGGHIDACVLGGLQVDEQGNLANWVVPGKMVPGMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRQCTMPLTA
LHAVHMLVTELAVFRFIDGKMWLTEIAEGCDLETVRAKTEAQFAVADDLLLPQGAL

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=215, Percent_Identity=48.3720930232558, Blast_Score=203, Evalue=9e-53,
Organism=Homo sapiens, GI11545841, Length=213, Percent_Identity=46.9483568075117, Blast_Score=192, Evalue=1e-49,
Organism=Escherichia coli, GI1788552, Length=216, Percent_Identity=92.5925925925926, Blast_Score=404, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17531517, Length=213, Percent_Identity=44.131455399061, Blast_Score=183, Evalue=5e-47,
Organism=Drosophila melanogaster, GI21358325, Length=211, Percent_Identity=51.6587677725119, Blast_Score=216, Evalue=8e-57,
Organism=Drosophila melanogaster, GI24655794, Length=211, Percent_Identity=51.6587677725119, Blast_Score=216, Evalue=1e-56,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 22814; Mature: 22814

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAKQRIARRVAQELCDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTKAHP
CCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCC
DLVNAGGQPCGVLPGAAMFDSAMSFALIRGGHIDACVLGGLQVDEQGNLANWVVPGKMVP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCCEEEEEECCCCCC
GMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRQCTMPLTALHAVHMLVTELAVFRFIDGK
CCCCCCCEECCCCEEEEEEHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
MWLTEIAEGCDLETVRAKTEAQFAVADDLLLPQGAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDAKQRIARRVAQELCDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTKAHP
CCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCC
DLVNAGGQPCGVLPGAAMFDSAMSFALIRGGHIDACVLGGLQVDEQGNLANWVVPGKMVP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCCEEEEEECCCCCC
GMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRQCTMPLTALHAVHMLVTELAVFRFIDGK
CCCCCCCEECCCCEEEEEEHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
MWLTEIAEGCDLETVRAKTEAQFAVADDLLLPQGAL
HHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]