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The map label for this gene is yfbG

Identifier: 218548295

GI number: 218548295

Start: 929252

End: 931234

Strand: Reverse

Name: yfbG

Synonym: EFER_0914

Alternate gene names: 218548295

Gene position: 931234-929252 (Counterclockwise)

Preceding gene: 218548296

Following gene: 218548294

Centisome position: 20.29

GC content: 46.39

Gene sequence:

>1983_bases
ATGAAAGCCGTTGTTTTTGCCTATCACGATATGGGCTGCCTTGGCGTACAAGCATTGCTGGACGCAGGTTATGAGATTAG
CGCTATTTTTACTCATGCGGATAATCCCGCAGAGAAAGTGTTTTATGGTTCAGTTTCCCGTCTGGCTGCCCTGGCTGGTA
TTCCAGTATATGCGCCAGATGATATTAATCATCCATTATGGGTGGAACGTATCGCGCAACTCGCACCAGACGTTATTTTC
TCATTCTATTACCGTAACTTGTTAAACAATGAGATTTTAAAACTGGCTCCGCACGGGGCTTTTAATTTGCACGGTTCTTT
ATTGCCGAAATACCGTGGTCGCGCACCACTGAACTGGGTACTGGAAAACGGCGAGAATGAAACTGGTGTGACATTACACA
GAATGGTAGCAAAAGCCGATGCAGGCGCTATTATCGCGCAACAGCGAGTAGCAATTGATCCTGAAGATGCCGCTCTGACT
CTGCATAAAAAGCTCTGCCAGTCGGCAAGTCAGATGCTCGAATATGCATTACCGGCAATTAAACAGGGGCAAACTCAAGA
AACTGCGCAAAACGAAAGTGAAGCCACCTACTTTGGCCGCAGAAAACCCGAAGACAGCTTCCTTGACTGGAACAAGCCGG
CAACAGTACTGCATAACATGGTACGTGCCGTAGCTGATCCATGGCCCGGCGCGTTCAGTTACGTCGGCACTCAAAAATTT
ACCATCTGGTCATCACGGGTTCATCCTCGTGTTAATGCCGCACAACCTGGTAGCGTGATTTCTGTTGCTCCATTCCTTAT
TGCATGCGGTGACGGTGCACTGGAAGTTATTACGGGCCAGTCGGTCGATGGCATTACCATGCAAGGTTCACAATTAGCCC
AGACTTTGGGGCTGGTTGAAGGTTCACGGCTAAACAGTCAACCAGTTTGTACTGTTCAGCGACGTACCCGAGTGCTAATC
CTCGGTGTTAATGGTTTTATTGGTAACCATCTGACCGAACGTTTACTACGTGAAGACCATTACGAAGTGTACGGGCTGGA
TATTGGTAGCGATGCCATTAGCCGGTTCCTTACACATCCTAATTTTCATTTTGTCGAAGGTGATATCAGTATCCACTCTG
AATGGATTGAGTATCACATTAAAAAATGTGACGTCGTCTTGCCACTCGTAGCAATCGCCACACCAATTGAATATACCCGT
AATCCACTACGTGTATTTGAATTAGATTTTGAAGAAAATCTGCGGATTATTCGTTACTGCGTTCAATACCATAAACGCAT
TATTTTCCCGTCCACGTCGGAAGTTTATGGTATGTGCACTGATAAATTCTTCGACGAGGATCATTCAAATTTAATTGTTG
GTCCGATTAACAAACCGCGTTGGATTTATTCTGTATCAAAACAGTTGCTTGATCGGGTTATTTGGGCGTATGGCGAAAAA
GAAGGTTTGCAGTTCACCCTCTTCCGTCCATTTAACTGGATGGGGCCACGGCTGGATAACCTTAATGCGGCACGAATTGG
TAGCTCGCGCGCCATTACCCAACTCATTCTCAACCTGGTGGAAGGATCGCCAATTAAACTGATTGATGGCGGAAAACAAA
AACGTTGCTTTACTGATATTCGCGATGGTATTGAAGCGTTATACCGCATTATCGAAAACACAGGTAATCGCTGTGACGGA
GAGATTATTAATATCGGCAACCCTGATAACGAAGCGAGTATTGAAGAACTGGGCAAGATGCTTCTGGCGAGCTTTGATAA
ACATCCGCTGCGCCAACATTTCCCACCATTTGCCGGTTTCCGCGTGGTAGAAAGCAGTAGCTATTACGGTAAAGGATATC
AGGACGTGGAGCACCGAAAACCGAGTATCCGCAATGCCCGCCGCTGCCTTGACTGGGAGCCAACCATCGATATGCAGGAA
ACCATTGACGAAACGCTGGATTTCTTCCTGCGCACAGTAGATATCGTGGAAAAATCGTCATGA

Upstream 100 bases:

>100_bases
ATATCGGCAGGATCTACAACGATGTCCGTGCCCGTCCACGCTACTTCGTTCAAAAAGTAATCCGTCCGGCAAGTTCTATA
GATATTGAGGAAAACCACTA

Downstream 100 bases:

>100_bases
CTAAAGTGGGCTTACGCATTGATGTCGACACCTTTCGTGGTACCCGCGAAGGCGTGCCACGTCTGCTGGAAACGTTGGAT
AAGCATAATATTCAGGCCAG

Product: bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase

Number of amino acids: Translated: 660; Mature: 660

Protein sequence:

>660_residues
MKAVVFAYHDMGCLGVQALLDAGYEISAIFTHADNPAEKVFYGSVSRLAALAGIPVYAPDDINHPLWVERIAQLAPDVIF
SFYYRNLLNNEILKLAPHGAFNLHGSLLPKYRGRAPLNWVLENGENETGVTLHRMVAKADAGAIIAQQRVAIDPEDAALT
LHKKLCQSASQMLEYALPAIKQGQTQETAQNESEATYFGRRKPEDSFLDWNKPATVLHNMVRAVADPWPGAFSYVGTQKF
TIWSSRVHPRVNAAQPGSVISVAPFLIACGDGALEVITGQSVDGITMQGSQLAQTLGLVEGSRLNSQPVCTVQRRTRVLI
LGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLTHPNFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIEYTR
NPLRVFELDFEENLRIIRYCVQYHKRIIFPSTSEVYGMCTDKFFDEDHSNLIVGPINKPRWIYSVSKQLLDRVIWAYGEK
EGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENTGNRCDG
EIINIGNPDNEASIEELGKMLLASFDKHPLRQHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNARRCLDWEPTIDMQE
TIDETLDFFLRTVDIVEKSS

Sequences:

>Translated_660_residues
MKAVVFAYHDMGCLGVQALLDAGYEISAIFTHADNPAEKVFYGSVSRLAALAGIPVYAPDDINHPLWVERIAQLAPDVIF
SFYYRNLLNNEILKLAPHGAFNLHGSLLPKYRGRAPLNWVLENGENETGVTLHRMVAKADAGAIIAQQRVAIDPEDAALT
LHKKLCQSASQMLEYALPAIKQGQTQETAQNESEATYFGRRKPEDSFLDWNKPATVLHNMVRAVADPWPGAFSYVGTQKF
TIWSSRVHPRVNAAQPGSVISVAPFLIACGDGALEVITGQSVDGITMQGSQLAQTLGLVEGSRLNSQPVCTVQRRTRVLI
LGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLTHPNFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIEYTR
NPLRVFELDFEENLRIIRYCVQYHKRIIFPSTSEVYGMCTDKFFDEDHSNLIVGPINKPRWIYSVSKQLLDRVIWAYGEK
EGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENTGNRCDG
EIINIGNPDNEASIEELGKMLLASFDKHPLRQHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNARRCLDWEPTIDMQE
TIDETLDFFLRTVDIVEKSS
>Mature_660_residues
MKAVVFAYHDMGCLGVQALLDAGYEISAIFTHADNPAEKVFYGSVSRLAALAGIPVYAPDDINHPLWVERIAQLAPDVIF
SFYYRNLLNNEILKLAPHGAFNLHGSLLPKYRGRAPLNWVLENGENETGVTLHRMVAKADAGAIIAQQRVAIDPEDAALT
LHKKLCQSASQMLEYALPAIKQGQTQETAQNESEATYFGRRKPEDSFLDWNKPATVLHNMVRAVADPWPGAFSYVGTQKF
TIWSSRVHPRVNAAQPGSVISVAPFLIACGDGALEVITGQSVDGITMQGSQLAQTLGLVEGSRLNSQPVCTVQRRTRVLI
LGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLTHPNFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIEYTR
NPLRVFELDFEENLRIIRYCVQYHKRIIFPSTSEVYGMCTDKFFDEDHSNLIVGPINKPRWIYSVSKQLLDRVIWAYGEK
EGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENTGNRCDG
EIINIGNPDNEASIEELGKMLLASFDKHPLRQHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNARRCLDWEPTIDMQE
TIDETLDFFLRTVDIVEKSS

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily

Homologues:

Organism=Homo sapiens, GI42516563, Length=346, Percent_Identity=26.5895953757225, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI21614513, Length=333, Percent_Identity=25.8258258258258, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI238814322, Length=217, Percent_Identity=29.4930875576037, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1788589, Length=660, Percent_Identity=87.2727272727273, Blast_Score=1223, Evalue=0.0,
Organism=Escherichia coli, GI1789683, Length=295, Percent_Identity=29.8305084745763, Blast_Score=138, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17539532, Length=349, Percent_Identity=25.214899713467, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI133930964, Length=261, Percent_Identity=24.5210727969349, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356223, Length=341, Percent_Identity=26.3929618768328, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28571984, Length=184, Percent_Identity=25.5434782608696, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI45550868, Length=184, Percent_Identity=25.5434782608696, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARNA_ESCF3 (B7LM76)

Other databases:

- EMBL:   CU928158
- RefSeq:   YP_002382086.1
- ProteinModelPortal:   B7LM76
- EnsemblBacteria:   EBESCT00000126011
- GeneID:   7119809
- GenomeReviews:   CU928158_GR
- KEGG:   efe:EFER_0914
- GeneTree:   EBGT00050000008811
- HOGENOM:   HBG298638
- ProtClustDB:   PRK08125
- BioCyc:   EFER585054:EFER_0914-MONOMER
- HAMAP:   MF_01166
- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.10.25.10
- Gene3D:   G3DSA:3.40.50.170
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF036506

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N; SSF50486 FMT_C_like; SSF53328 formyl_transf

EC number: =2.1.2.13; =1.1.1.305

Molecular weight: Translated: 74250; Mature: 74250

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: ACT_SITE 104-104 ACT_SITE 434-434 ACT_SITE 619-619 BINDING 114-114 BINDING 347-347 BINDING 393-393 BINDING 398-398 BINDING 460-460 BINDING 492-492 BINDING 613-613

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVVFAYHDMGCLGVQALLDAGYEISAIFTHADNPAEKVFYGSVSRLAALAGIPVYAPD
CCEEEEEECCCCHHHHHHHHHCCCEEEEEEEECCCHHHHHHHCCHHHHHHHHCCCEECCC
DINHPLWVERIAQLAPDVIFSFYYRNLLNNEILKLAPHGAFNLHGSLLPKYRGRAPLNWV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCE
LENGENETGVTLHRMVAKADAGAIIAQQRVAIDPEDAALTLHKKLCQSASQMLEYALPAI
EECCCCCCCHHHHHHHHHCCCCCEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KQGQTQETAQNESEATYFGRRKPEDSFLDWNKPATVLHNMVRAVADPWPGAFSYVGTQKF
CCCCCHHHHCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHCCCEEE
TIWSSRVHPRVNAAQPGSVISVAPFLIACGDGALEVITGQSVDGITMQGSQLAQTLGLVE
EEECCCCCCCCCCCCCCCEEEECCCCEECCCCCEEEEECCCCCCEEECHHHHHHHHHHCC
GSRLNSQPVCTVQRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLTHP
CCCCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCC
NFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYC
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECHHHCHHHHHHH
VQYHKRIIFPSTSEVYGMCTDKFFDEDHSNLIVGPINKPRWIYSVSKQLLDRVIWAYGEK
HHHHHEEECCCCCHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
EGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDI
CCCEEEEECCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHH
RDGIEALYRIIENTGNRCDGEIINIGNPDNEASIEELGKMLLASFDKHPLRQHFPPFAGF
HHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCE
RVVESSSYYGKGYQDVEHRKPSIRNARRCLDWEPTIDMQETIDETLDFFLRTVDIVEKSS
EEEECCCCCCCCCCHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKAVVFAYHDMGCLGVQALLDAGYEISAIFTHADNPAEKVFYGSVSRLAALAGIPVYAPD
CCEEEEEECCCCHHHHHHHHHCCCEEEEEEEECCCHHHHHHHCCHHHHHHHHCCCEECCC
DINHPLWVERIAQLAPDVIFSFYYRNLLNNEILKLAPHGAFNLHGSLLPKYRGRAPLNWV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCE
LENGENETGVTLHRMVAKADAGAIIAQQRVAIDPEDAALTLHKKLCQSASQMLEYALPAI
EECCCCCCCHHHHHHHHHCCCCCEEECCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KQGQTQETAQNESEATYFGRRKPEDSFLDWNKPATVLHNMVRAVADPWPGAFSYVGTQKF
CCCCCHHHHCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHCCCEEE
TIWSSRVHPRVNAAQPGSVISVAPFLIACGDGALEVITGQSVDGITMQGSQLAQTLGLVE
EEECCCCCCCCCCCCCCCEEEECCCCEECCCCCEEEEECCCCCCEEECHHHHHHHHHHCC
GSRLNSQPVCTVQRRTRVLILGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLTHP
CCCCCCCCCEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCC
NFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYC
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECHHHCHHHHHHH
VQYHKRIIFPSTSEVYGMCTDKFFDEDHSNLIVGPINKPRWIYSVSKQLLDRVIWAYGEK
HHHHHEEECCCCCHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
EGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDI
CCCEEEEECCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHH
RDGIEALYRIIENTGNRCDGEIINIGNPDNEASIEELGKMLLASFDKHPLRQHFPPFAGF
HHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCE
RVVESSSYYGKGYQDVEHRKPSIRNARRCLDWEPTIDMQETIDETLDFFLRTVDIVEKSS
EEEECCCCCCCCCCHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA