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The map label for this gene is pta [H]

Identifier: 218548253

GI number: 218548253

Start: 884715

End: 886859

Strand: Reverse

Name: pta [H]

Synonym: EFER_0871

Alternate gene names: 218548253

Gene position: 886859-884715 (Counterclockwise)

Preceding gene: 218548254

Following gene: 218548247

Centisome position: 19.33

GC content: 53.8

Gene sequence:

>2145_bases
GTGTCCCGTATTATTATGCTGATCCCTACCGGAACAAGCGTCGGTCTGACCAGCGTCAGCCTTGGCGTTGTCCGCGCTAT
GGAACGTAAAGGCGTTCGCCTGAGCGTCTTTAAGCCTATCGCTCAACCGCGTTCCGGTAGCGATGCTCCTGACCAGACCA
CAGCTATCGTCCGCGCAAACTCCACGCTGGCAACGGCTGAACCTCTGAAAATGAGCCACGTTGAGTCTCTGCTTTCCAGC
AATCAAAAAGATGTGCTGATGGAAGAGATCATCGCCAACTATCATGCCAACACCAAAGATGCTGAAGTCGTTCTGGTTGA
AGGTCTGGTTCCAACACGTAAACATCAGTTTGCTCAGTCTCTGAACTATGAAATTGCGAAAACGCTGAACGCGGAAATCG
TCTTTGTCATGTCTCAGGGTTCTGACACGCCAGAACAACTGAAAGAGCGTATCGAACTGACGCGCAGCAGCTTCGGCGGT
GCCAAAAACACCAATATCATCGGCGTTATCGTTAACAAACTGAACGCGCCCGTTGACGACCAGGGGCGCACTCGCCCGGA
TCTGTCTGAGATTTTCGACGACTCTTCTAAAGCGCATGTCACCAAGTTTGATCCAGCGAAACTGCTGGAATCCAGCCCGC
TGCCAGTGCTTGGCATCGTGCCGTGGAGCTTTGATCTGATCGCAACCCGTGCGATCGATATGGCGCGTCACCTGAACGCA
ACCATTATTAACGAAGGTGATATCAACACTCGCCGTGTTAAATCCGTTACGTTCTGTGCCCGTAGCATTCCGCATATGCT
TGAGCACTTCCGTGCCGGTTCTCTGCTGGTAACTTCCGCAGACCGTCCTGACGTACTGGTTGCCGCTTGCCTGGCTGCGA
TGAATGGCGTAGAAATTGGCGCTCTGCTGCTGACTGGCGGCTACGAAATGGACGCACGTATTTCTAAACTGTGCGAGCGT
GCGTTTGCTACTGGCCTGCCGGTATTTATGGTGAACACCAACACCTGGCAGACTTCTTTAAGCCTGCAGAGCTTCAATCT
GGAAGTTCCGGTTGACGATCACGAGCGTATCGAGAAAGTTCAGGAATACGTTGCTAACTACATCAACGCTGACTGGATCG
AATCTCTGACGGCTACTTCCGAGCGCAGCCGTCGTCTGTCTCCGCCAGCATTCCGCTATCAGCTGACCGAACTGGCACGC
AAAGCCGGTAAGCGCATTGTTCTGCCGGAAGGTGACGAACCACGTACAGTGAAAGCAGCGGCTATTTGTGCGGAACGTGG
TATCGCAACTTGTGTGCTTCTGGGTAACCCGGAAGAAATCAACCGTGTTGCGGCATCTCAGGGCGTAGAACTGGGTGCTG
GCATTGAAATCGTCGATCCAGAAGTTGTTCGCGAAAGCTATGTTGGCCGCCTGGTTGAACTGCGTAAGAGCAAAGGTATG
ACCGAAACCGTTGCCCGCGAACAGCTGGAAGACAACGTGGTTCTCGGCACTCTGATGCTGGAGCAGGATGAAGTTGACGG
TCTGGTTTCCGGTGCTGTTCACACCACCGCAAACACCATCCGTCCGCCGCTGCAGCTGATCAAAACTGCACCGGGTAGCT
CTTTAGTATCTTCTGTGTTCTTCATGCTGCTGCCGGAACAGGTTTACGTTTACGGTGACTGCGCGATCAACCCGGACCCG
ACCGCTGAGCAGCTGGCAGAAATCGCGATTCAGTCTGCTGATTCTGCTACTGCTTTTGGTATCGAACCGCGTGTAGCCAT
GCTCTCCTACTCCACCGGGACTTCTGGTGCAGGCAGCGATGTAGAGAAAGTTCGCGAAGCAACTCGTCTGGCGCAGGAAA
AACGTCCTGACCTGATGATCGACGGCCCGCTGCAGTACGATGCTGCAGTAATGGCTGACGTTGCGAAATCTAAAGCACCG
AACTCTCCGGTTGCAGGTCGCGCTACCGTGTTCATCTTCCCGGATCTGAACACCGGTAACACCACCTACAAAGCGGTACA
GCGTTCTGCTGACCTGATCTCCATCGGGCCGATGCTGCAGGGTATGCGCAAGCCGGTTAACGACTTGTCTCGAGGCGCAC
TGGTTGACGATATCGTCTACACTATCGCTCTGACCGCGATCCAGTCTGCACAACAGCAGAAGTAA

Upstream 100 bases:

>100_bases
GACGCGAGCCGTCTGACTGCCTGATTTCACACCGCCAGCCCTGCTGGCGGTGCTGTTTTGTAACCCGCCCACCTTCGGCG
GTAACGAAAGAGGATAAATC

Downstream 100 bases:

>100_bases
TCTTTTCTGTTTAGCGTAAAAGACTAAAAGCAAAATCCGGAAATAGTGATTATTTCCGGATTTTTTATTTTAGAATCAGT
TACAACAACTCTCTCGCAGC

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MSRIIMLIPTGTSVGLTSVSLGVVRAMERKGVRLSVFKPIAQPRSGSDAPDQTTAIVRANSTLATAEPLKMSHVESLLSS
NQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGSDTPEQLKERIELTRSSFGG
AKNTNIIGVIVNKLNAPVDDQGRTRPDLSEIFDDSSKAHVTKFDPAKLLESSPLPVLGIVPWSFDLIATRAIDMARHLNA
TIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCER
AFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERSRRLSPPAFRYQLTELAR
KAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELGAGIEIVDPEVVRESYVGRLVELRKSKGM
TETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDP
TAEQLAEIAIQSADSATAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAP
NSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQK

Sequences:

>Translated_714_residues
MSRIIMLIPTGTSVGLTSVSLGVVRAMERKGVRLSVFKPIAQPRSGSDAPDQTTAIVRANSTLATAEPLKMSHVESLLSS
NQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGSDTPEQLKERIELTRSSFGG
AKNTNIIGVIVNKLNAPVDDQGRTRPDLSEIFDDSSKAHVTKFDPAKLLESSPLPVLGIVPWSFDLIATRAIDMARHLNA
TIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCER
AFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERSRRLSPPAFRYQLTELAR
KAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELGAGIEIVDPEVVRESYVGRLVELRKSKGM
TETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDP
TAEQLAEIAIQSADSATAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAP
NSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQK
>Mature_713_residues
SRIIMLIPTGTSVGLTSVSLGVVRAMERKGVRLSVFKPIAQPRSGSDAPDQTTAIVRANSTLATAEPLKMSHVESLLSSN
QKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGSDTPEQLKERIELTRSSFGGA
KNTNIIGVIVNKLNAPVDDQGRTRPDLSEIFDDSSKAHVTKFDPAKLLESSPLPVLGIVPWSFDLIATRAIDMARHLNAT
IINEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERA
FATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERSRRLSPPAFRYQLTELARK
AGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPEEINRVAASQGVELGAGIEIVDPEVVRESYVGRLVELRKSKGMT
ETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPT
AEQLAEIAIQSADSATAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPN
SPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQK

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0857

COG function: function code R; BioD-like N-terminal domain of phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=714, Percent_Identity=96.6386554621849, Blast_Score=1412, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=318, Percent_Identity=38.3647798742138, Blast_Score=217, Evalue=3e-57,
Organism=Escherichia coli, GI1788806, Length=349, Percent_Identity=31.2320916905444, Blast_Score=167, Evalue=3e-42,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010766
- InterPro:   IPR016475
- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF07085 DRTGG; PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 77319; Mature: 77188

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIIMLIPTGTSVGLTSVSLGVVRAMERKGVRLSVFKPIAQPRSGSDAPDQTTAIVRAN
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEEEC
STLATAEPLKMSHVESLLSSNQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQS
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHH
LNYEIAKTLNAEIVFVMSQGSDTPEQLKERIELTRSSFGGAKNTNIIGVIVNKLNAPVDD
CCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHCCCCCC
QGRTRPDLSEIFDDSSKAHVTKFDPAKLLESSPLPVLGIVPWSFDLIATRAIDMARHLNA
CCCCCCCHHHHHCCCCCCEEEECCHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCC
TIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIG
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCEEE
ALLLTGGYEMDARISKLCERAFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKV
EEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEEEEECCCCHHHHHHHH
QEYVANYINADWIESLTATSERSRRLSPPAFRYQLTELARKAGKRIVLPEGDEPRTVKAA
HHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHH
AICAERGIATCVLLGNPEEINRVAASQGVELGAGIEIVDPEVVRESYVGRLVELRKSKGM
HHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCC
TETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVF
HHHHHHHHHCCCEEEEEEEECCHHHHHHHHCHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
FMLLPEQVYVYGDCAINPDPTAEQLAEIAIQSADSATAFGIEPRVAMLSYSTGTSGAGSD
HHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCCCHH
VEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGN
HHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCC
TTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQK
HHHHHHHHCCCEEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRIIMLIPTGTSVGLTSVSLGVVRAMERKGVRLSVFKPIAQPRSGSDAPDQTTAIVRAN
CEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEEEC
STLATAEPLKMSHVESLLSSNQKDVLMEEIIANYHANTKDAEVVLVEGLVPTRKHQFAQS
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHH
LNYEIAKTLNAEIVFVMSQGSDTPEQLKERIELTRSSFGGAKNTNIIGVIVNKLNAPVDD
CCHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHCCCCCC
QGRTRPDLSEIFDDSSKAHVTKFDPAKLLESSPLPVLGIVPWSFDLIATRAIDMARHLNA
CCCCCCCHHHHHCCCCCCEEEECCHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCC
TIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIG
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCEEE
ALLLTGGYEMDARISKLCERAFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKV
EEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEEEEECCCCHHHHHHHH
QEYVANYINADWIESLTATSERSRRLSPPAFRYQLTELARKAGKRIVLPEGDEPRTVKAA
HHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHH
AICAERGIATCVLLGNPEEINRVAASQGVELGAGIEIVDPEVVRESYVGRLVELRKSKGM
HHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCC
TETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVF
HHHHHHHHHCCCEEEEEEEECCHHHHHHHHCHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
FMLLPEQVYVYGDCAINPDPTAEQLAEIAIQSADSATAFGIEPRVAMLSYSTGTSGAGSD
HHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCCCHH
VEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGN
HHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCC
TTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQK
HHHHHHHHCCCEEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883769; 7918659; 9205837; 9278503; 2536666 [H]