| Definition | Bacillus cereus B4264, complete genome. |
|---|---|
| Accession | NC_011725 |
| Length | 5,419,036 |
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The map label for this gene is yvgN [H]
Identifier: 218233093
GI number: 218233093
Start: 194417
End: 195250
Strand: Reverse
Name: yvgN [H]
Synonym: BCB4264_A0222
Alternate gene names: 218233093
Gene position: 195250-194417 (Counterclockwise)
Preceding gene: 218232312
Following gene: 218230899
Centisome position: 3.6
GC content: 34.53
Gene sequence:
>834_bases ATGATTTTAACAAGTTTAAAAGACTATACAACATTACATAACGGTGTAAAAATGCCTTGGTTTGGTTTAGGTGTTTTTAA AGTAGAAGATGGTTCAGAAGTAATTGATTCTGTAAAAGCAGCAATTAAAAATGGCTACCGCAGCATCGATACTGCAGCAA TCTATCAAAATGAAGAAGGCGTTGGGCAAGCGATTCGTGAATCCGGTGTTTCACGTGAAGAATTATTTATTACCTCAAAA GTATGGAATAGCGATCAAGGATATGAAACAACACTTCAAGCATTTGAAACTACATTAGAGAAATTAGGTCTAGAATATTT AGATTTATATTTAGTACATTGGCCTGTAAAAGGGAAATATACTGAATCATGGAAAGCATTAGAAACACTTTATAAAGATG GCCGTGTTCGCGCTATCGGTGTGAGTAATTTCCACATTCACCACTTACAAGACGTATTTGAAATTGCTGAAATTAAGCCA ATGGTCAACCAAGTGGAATATCACCCACGTTTAGCACAAGAAGAGTTACATGCATTCTGTAAAGAACATAATATCCAGCT TGAAGCTTGGTCACCATTAATGCAAGGACAACTACTAGATAATCCAACGTTACAAGAAATTGCGACAAAATATAATAAAT CAACTGCGCAAATTATTTTACGTTGGGATTTACAAAACGAAGTTGTAACAATTCCCAAATCAATTAAAGAACATCGCATT ATTGAAAATGCAAACATCTTCGACTTTGAATTAAGTGCTGATGATATGAAAGCAATTCAAGCTTTAAATGAAGATCGTCG TGTTGGTCCAGATCCAGATAACTTTAACTTCTAG
Upstream 100 bases:
>100_bases TCCACAGCTGAGGGTCTCAAAACTTTATACGAATATAATTTTTCAGAGGCAATTCAAAAAGCAGTAGAAGCAACAAACAA AAAAGCTAGGGGGAAATAAT
Downstream 100 bases:
>100_bases TAGAAAAACCACTGCCATATGCAGTGGTTTTTCTATTTAAGAAAACTGAAAATTTAAACTACATTTCATTTAGTTGACAC TTCATTATTCAAGGTGTAAG
Product: oxidoreductase, aldo/keto reductase family
Products: NA
Alternate protein names: GR; Methylglyoxal reductase [H]
Number of amino acids: Translated: 277; Mature: 277
Protein sequence:
>277_residues MILTSLKDYTTLHNGVKMPWFGLGVFKVEDGSEVIDSVKAAIKNGYRSIDTAAIYQNEEGVGQAIRESGVSREELFITSK VWNSDQGYETTLQAFETTLEKLGLEYLDLYLVHWPVKGKYTESWKALETLYKDGRVRAIGVSNFHIHHLQDVFEIAEIKP MVNQVEYHPRLAQEELHAFCKEHNIQLEAWSPLMQGQLLDNPTLQEIATKYNKSTAQIILRWDLQNEVVTIPKSIKEHRI IENANIFDFELSADDMKAIQALNEDRRVGPDPDNFNF
Sequences:
>Translated_277_residues MILTSLKDYTTLHNGVKMPWFGLGVFKVEDGSEVIDSVKAAIKNGYRSIDTAAIYQNEEGVGQAIRESGVSREELFITSK VWNSDQGYETTLQAFETTLEKLGLEYLDLYLVHWPVKGKYTESWKALETLYKDGRVRAIGVSNFHIHHLQDVFEIAEIKP MVNQVEYHPRLAQEELHAFCKEHNIQLEAWSPLMQGQLLDNPTLQEIATKYNKSTAQIILRWDLQNEVVTIPKSIKEHRI IENANIFDFELSADDMKAIQALNEDRRVGPDPDNFNF >Mature_277_residues MILTSLKDYTTLHNGVKMPWFGLGVFKVEDGSEVIDSVKAAIKNGYRSIDTAAIYQNEEGVGQAIRESGVSREELFITSK VWNSDQGYETTLQAFETTLEKLGLEYLDLYLVHWPVKGKYTESWKALETLYKDGRVRAIGVSNFHIHHLQDVFEIAEIKP MVNQVEYHPRLAQEELHAFCKEHNIQLEAWSPLMQGQLLDNPTLQEIATKYNKSTAQIILRWDLQNEVVTIPKSIKEHRI IENANIFDFELSADDMKAIQALNEDRRVGPDPDNFNF
Specific function: Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis [H]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=291, Percent_Identity=42.9553264604811, Blast_Score=231, Evalue=7e-61, Organism=Homo sapiens, GI5174391, Length=291, Percent_Identity=42.9553264604811, Blast_Score=231, Evalue=7e-61, Organism=Homo sapiens, GI223468663, Length=298, Percent_Identity=38.9261744966443, Blast_Score=201, Evalue=4e-52, Organism=Homo sapiens, GI4502049, Length=293, Percent_Identity=40.9556313993174, Blast_Score=185, Evalue=3e-47, Organism=Homo sapiens, GI5174695, Length=307, Percent_Identity=36.4820846905537, Blast_Score=185, Evalue=5e-47, Organism=Homo sapiens, GI291291012, Length=272, Percent_Identity=38.2352941176471, Blast_Score=184, Evalue=8e-47, Organism=Homo sapiens, GI310109922, Length=290, Percent_Identity=37.5862068965517, Blast_Score=182, Evalue=3e-46, Organism=Homo sapiens, GI5453543, Length=310, Percent_Identity=35.4838709677419, Blast_Score=179, Evalue=3e-45, Organism=Homo sapiens, GI310109920, Length=310, Percent_Identity=35.4838709677419, Blast_Score=179, Evalue=3e-45, Organism=Homo sapiens, GI93277124, Length=304, Percent_Identity=35.1973684210526, Blast_Score=178, Evalue=5e-45, Organism=Homo sapiens, GI45446745, Length=310, Percent_Identity=35.4838709677419, Blast_Score=178, Evalue=5e-45, Organism=Homo sapiens, GI4503285, Length=310, Percent_Identity=35.4838709677419, Blast_Score=178, Evalue=5e-45, Organism=Homo sapiens, GI24497583, Length=293, Percent_Identity=35.8361774744027, Blast_Score=173, Evalue=2e-43, Organism=Homo sapiens, GI24497585, Length=295, Percent_Identity=35.5932203389831, Blast_Score=172, Evalue=3e-43, Organism=Homo sapiens, GI300116273, Length=283, Percent_Identity=35.3356890459364, Blast_Score=162, Evalue=4e-40, Organism=Homo sapiens, GI300116271, Length=285, Percent_Identity=35.7894736842105, Blast_Score=155, Evalue=5e-38, Organism=Homo sapiens, GI310109924, Length=169, Percent_Identity=35.5029585798817, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI310109926, Length=114, Percent_Identity=41.2280701754386, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI207028673, Length=114, Percent_Identity=41.2280701754386, Blast_Score=89, Evalue=6e-18, Organism=Escherichia coli, GI87082198, Length=269, Percent_Identity=46.4684014869888, Blast_Score=262, Evalue=2e-71, Organism=Escherichia coli, GI1786400, Length=261, Percent_Identity=37.9310344827586, Blast_Score=172, Evalue=3e-44, Organism=Escherichia coli, GI1788081, Length=260, Percent_Identity=32.3076923076923, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI1788070, Length=303, Percent_Identity=23.1023102310231, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI87081735, Length=177, Percent_Identity=27.1186440677966, Blast_Score=69, Evalue=3e-13, Organism=Caenorhabditis elegans, GI71998625, Length=267, Percent_Identity=43.8202247191011, Blast_Score=216, Evalue=1e-56, Organism=Caenorhabditis elegans, GI17564128, Length=300, Percent_Identity=37, Blast_Score=205, Evalue=2e-53, Organism=Caenorhabditis elegans, GI17537075, Length=297, Percent_Identity=39.3939393939394, Blast_Score=192, Evalue=2e-49, Organism=Caenorhabditis elegans, GI17537077, Length=292, Percent_Identity=38.3561643835616, Blast_Score=187, Evalue=5e-48, Organism=Caenorhabditis elegans, GI17561298, Length=270, Percent_Identity=35.1851851851852, Blast_Score=181, Evalue=3e-46, Organism=Caenorhabditis elegans, GI17537079, Length=305, Percent_Identity=34.0983606557377, Blast_Score=172, Evalue=2e-43, Organism=Caenorhabditis elegans, GI17550248, Length=300, Percent_Identity=36.6666666666667, Blast_Score=171, Evalue=4e-43, Organism=Caenorhabditis elegans, GI17538386, Length=271, Percent_Identity=34.6863468634686, Blast_Score=170, Evalue=9e-43, Organism=Caenorhabditis elegans, GI17552492, Length=273, Percent_Identity=31.8681318681319, Blast_Score=166, Evalue=1e-41, Organism=Caenorhabditis elegans, GI17562292, Length=276, Percent_Identity=32.9710144927536, Blast_Score=165, Evalue=3e-41, Organism=Caenorhabditis elegans, GI17566692, Length=288, Percent_Identity=33.3333333333333, Blast_Score=154, Evalue=6e-38, Organism=Caenorhabditis elegans, GI17561300, Length=273, Percent_Identity=31.5018315018315, Blast_Score=142, Evalue=2e-34, Organism=Caenorhabditis elegans, GI17550246, Length=81, Percent_Identity=50.6172839506173, Blast_Score=73, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6324694, Length=288, Percent_Identity=37.5, Blast_Score=195, Evalue=5e-51, Organism=Saccharomyces cerevisiae, GI6320576, Length=285, Percent_Identity=38.2456140350877, Blast_Score=191, Evalue=8e-50, Organism=Saccharomyces cerevisiae, GI6321896, Length=317, Percent_Identity=34.0694006309148, Blast_Score=173, Evalue=2e-44, Organism=Saccharomyces cerevisiae, GI6319625, Length=299, Percent_Identity=36.7892976588629, Blast_Score=172, Evalue=4e-44, Organism=Saccharomyces cerevisiae, GI6322556, Length=260, Percent_Identity=34.6153846153846, Blast_Score=169, Evalue=3e-43, Organism=Saccharomyces cerevisiae, GI6320079, Length=283, Percent_Identity=34.2756183745583, Blast_Score=155, Evalue=5e-39, Organism=Drosophila melanogaster, GI24663317, Length=292, Percent_Identity=40.4109589041096, Blast_Score=199, Evalue=1e-51, Organism=Drosophila melanogaster, GI24662789, Length=293, Percent_Identity=37.542662116041, Blast_Score=198, Evalue=4e-51, Organism=Drosophila melanogaster, GI20129731, Length=296, Percent_Identity=37.5, Blast_Score=187, Evalue=8e-48, Organism=Drosophila melanogaster, GI24657054, Length=301, Percent_Identity=37.2093023255814, Blast_Score=181, Evalue=6e-46, Organism=Drosophila melanogaster, GI24644950, Length=302, Percent_Identity=33.4437086092715, Blast_Score=176, Evalue=2e-44, Organism=Drosophila melanogaster, GI21356425, Length=301, Percent_Identity=34.21926910299, Blast_Score=170, Evalue=7e-43, Organism=Drosophila melanogaster, GI24662785, Length=291, Percent_Identity=38.8316151202749, Blast_Score=169, Evalue=3e-42, Organism=Drosophila melanogaster, GI45553081, Length=289, Percent_Identity=33.5640138408304, Blast_Score=169, Evalue=3e-42, Organism=Drosophila melanogaster, GI221378297, Length=322, Percent_Identity=31.3664596273292, Blast_Score=168, Evalue=3e-42, Organism=Drosophila melanogaster, GI24662781, Length=293, Percent_Identity=38.5665529010239, Blast_Score=167, Evalue=5e-42, Organism=Drosophila melanogaster, GI281366140, Length=257, Percent_Identity=34.2412451361868, Blast_Score=151, Evalue=5e-37,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: =1.1.1.283 [H]
Molecular weight: Translated: 31800; Mature: 31800
Theoretical pI: Translated: 4.88; Mature: 4.88
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MILTSLKDYTTLHNGVKMPWFGLGVFKVEDGSEVIDSVKAAIKNGYRSIDTAAIYQNEEG CCCCCCHHHHHHHCCCCCCEEECEEEEECCCHHHHHHHHHHHHCCCCCCCHHHEEECCCH VGQAIRESGVSREELFITSKVWNSDQGYETTLQAFETTLEKLGLEYLDLYLVHWPVKGKY HHHHHHHCCCCHHHEEEEHHHCCCCCCHHHHHHHHHHHHHHHCHHHEEEEHEEECCCCCC TESWKALETLYKDGRVRAIGVSNFHIHHLQDVFEIAEIKPMVNQVEYHPRLAQEELHAFC CHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH KEHNIQLEAWSPLMQGQLLDNPTLQEIATKYNKSTAQIILRWDLQNEVVTIPKSIKEHRI HHCCCEEEECCHHHCCCCCCCCCHHHHHHHHCCCEEEEEEEEECCCCEEECCHHHHHHHH IENANIFDFELSADDMKAIQALNEDRRVGPDPDNFNF HCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCC >Mature Secondary Structure MILTSLKDYTTLHNGVKMPWFGLGVFKVEDGSEVIDSVKAAIKNGYRSIDTAAIYQNEEG CCCCCCHHHHHHHCCCCCCEEECEEEEECCCHHHHHHHHHHHHCCCCCCCHHHEEECCCH VGQAIRESGVSREELFITSKVWNSDQGYETTLQAFETTLEKLGLEYLDLYLVHWPVKGKY HHHHHHHCCCCHHHEEEEHHHCCCCCCHHHHHHHHHHHHHHHCHHHEEEEHEEECCCCCC TESWKALETLYKDGRVRAIGVSNFHIHHLQDVFEIAEIKPMVNQVEYHPRLAQEELHAFC CHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH KEHNIQLEAWSPLMQGQLLDNPTLQEIATKYNKSTAQIILRWDLQNEVVTIPKSIKEHRI HHCCCEEEECCHHHCCCCCCCCCHHHHHHHHCCCEEEEEEEEECCCCEEECCHHHHHHHH IENANIFDFELSADDMKAIQALNEDRRVGPDPDNFNF HCCCCEEEEEECHHHHHHHHHHCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9639930; 9384377 [H]