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The map label for this gene is arlR [H]

Identifier: 218232832

GI number: 218232832

Start: 604840

End: 605511

Strand: Reverse

Name: arlR [H]

Synonym: BCB4264_A0623

Alternate gene names: 218232832

Gene position: 605511-604840 (Counterclockwise)

Preceding gene: 218231597

Following gene: 218231013

Centisome position: 11.17

GC content: 34.38

Gene sequence:

>672_bases
ATGGTAAAAATTTTATTAGTAGACGATGAAGAACGTATGTTACGATTATTAGATCTGTTCTTAAGCCCTCGCGGCTATTT
TTGTATGAAAGCTACCTCTGGCCTTGAAGCACTAAAATTAATCGAACAAAAAGAATTCGATATTATTTTATTAGATGTTA
TGATGCCAAGTATGGATGGATGGGATACTTGCTATCAAATTCGTCAAATTTCCAACGTTCCTATCATTATGTTAACAGCT
CGCAACCAAAACTACGATATGGTGAAAGGCCTCACGATGGGCGCAGATGATTATATTACAAAACCATTTGATGAGCATGT
ATTAGTCGCACGAATCGAGGCTATATTACGCCGTACAAAAAAAGATGGCTTTGTTAGTTTCAATGGTATTGAGTGGGATA
AAACGAAACATACTGTCACAGTTTATGATGAAAAAATCTCATTAACTCCTATCGAATTTTCGTTACTCGGACTATTTTTA
CAAAATACAAACCGTGCTTATAGCCGAGATGATTTAATCGAAAAAATTTGGGGCTATGAAACAGATATCGAATATAGAAC
AATTGATTCACACATTCGTAATATCCGTGATAAACTACGCAAAAAAGGATTTCCTATTGAAGATTACCTAGAAACGGTCT
ATAAAGTCGGATATAAATGGAAAAGTGAATAA

Upstream 100 bases:

>100_bases
GCGAAAAAATCAGCCCTCCATTCAATCACATAAAAAGAGTTTTTTATTATTTTCATGTAAACTATACAAGTAGAATGAAC
AGTTTGGGGTGCACAAGATT

Downstream 100 bases:

>100_bases
TTACTTCGGTCAGTGGGAAATCGTATACCACTGACTCTTTATTATGAATAAGGTATGGTGAAAAAATGAGTAAACTTTCC
CTTAAAATTGGGACATACTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MVKILLVDDEERMLRLLDLFLSPRGYFCMKATSGLEALKLIEQKEFDIILLDVMMPSMDGWDTCYQIRQISNVPIIMLTA
RNQNYDMVKGLTMGADDYITKPFDEHVLVARIEAILRRTKKDGFVSFNGIEWDKTKHTVTVYDEKISLTPIEFSLLGLFL
QNTNRAYSRDDLIEKIWGYETDIEYRTIDSHIRNIRDKLRKKGFPIEDYLETVYKVGYKWKSE

Sequences:

>Translated_223_residues
MVKILLVDDEERMLRLLDLFLSPRGYFCMKATSGLEALKLIEQKEFDIILLDVMMPSMDGWDTCYQIRQISNVPIIMLTA
RNQNYDMVKGLTMGADDYITKPFDEHVLVARIEAILRRTKKDGFVSFNGIEWDKTKHTVTVYDEKISLTPIEFSLLGLFL
QNTNRAYSRDDLIEKIWGYETDIEYRTIDSHIRNIRDKLRKKGFPIEDYLETVYKVGYKWKSE
>Mature_223_residues
MVKILLVDDEERMLRLLDLFLSPRGYFCMKATSGLEALKLIEQKEFDIILLDVMMPSMDGWDTCYQIRQISNVPIIMLTA
RNQNYDMVKGLTMGADDYITKPFDEHVLVARIEAILRRTKKDGFVSFNGIEWDKTKHTVTVYDEKISLTPIEFSLLGLFL
QNTNRAYSRDDLIEKIWGYETDIEYRTIDSHIRNIRDKLRKKGFPIEDYLETVYKVGYKWKSE

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=34.9557522123894, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=34.6666666666667, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=34.0909090909091, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=32.3008849557522, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=36.5217391304348, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1790860, Length=202, Percent_Identity=32.1782178217822, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=30.4545454545455, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=30.3571428571429, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=31.6742081447964, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=31.8181818181818, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=31.140350877193, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=30.6666666666667, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=27.7272727272727, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=27.0386266094421, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788550, Length=103, Percent_Identity=35.9223300970874, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790437, Length=157, Percent_Identity=29.9363057324841, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=120, Percent_Identity=34.1666666666667, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=34.2342342342342, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788905, Length=119, Percent_Identity=32.7731092436975, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1789149, Length=128, Percent_Identity=31.25, Blast_Score=61, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=112, Percent_Identity=32.1428571428571, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26258; Mature: 26258

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKILLVDDEERMLRLLDLFLSPRGYFCMKATSGLEALKLIEQKEFDIILLDVMMPSMDG
CEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCC
WDTCYQIRQISNVPIIMLTARNQNYDMVKGLTMGADDYITKPFDEHVLVARIEAILRRTK
HHHHHHHHHCCCCCEEEEEECCCCCHHHHCEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
KDGFVSFNGIEWDKTKHTVTVYDEKISLTPIEFSLLGLFLQNTNRAYSRDDLIEKIWGYE
CCCCEEECCEEECCCCCEEEEEECEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
TDIEYRTIDSHIRNIRDKLRKKGFPIEDYLETVYKVGYKWKSE
CCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEECCC
>Mature Secondary Structure
MVKILLVDDEERMLRLLDLFLSPRGYFCMKATSGLEALKLIEQKEFDIILLDVMMPSMDG
CEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCC
WDTCYQIRQISNVPIIMLTARNQNYDMVKGLTMGADDYITKPFDEHVLVARIEAILRRTK
HHHHHHHHHCCCCCEEEEEECCCCCHHHHCEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
KDGFVSFNGIEWDKTKHTVTVYDEKISLTPIEFSLLGLFLQNTNRAYSRDDLIEKIWGYE
CCCCEEECCEEECCCCCEEEEEECEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
TDIEYRTIDSHIRNIRDKLRKKGFPIEDYLETVYKVGYKWKSE
CCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA