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The map label for this gene is resE [H]

Identifier: 218231013

GI number: 218231013

Start: 603320

End: 604774

Strand: Reverse

Name: resE [H]

Synonym: BCB4264_A0622

Alternate gene names: 218231013

Gene position: 604774-603320 (Counterclockwise)

Preceding gene: 218232832

Following gene: 218235198

Centisome position: 11.16

GC content: 33.54

Gene sequence:

>1455_bases
ATGAGTAAACTTTCCCTTAAAATTGGGACATACTTTTTAATATTAGCTTTATGTATTGAAACAATTGCCTTCGTATCTTT
TTATAAAAGTCTTTCAAAAATGCGTATTGTAGAGGAAACAGATGCTCTTTTAGAGAAAGGTAATCGCTATAGTAAAAAAA
TTAAAAGCCGCGAGAGACGGGATGAATATTATAAAGAAATGAAACACGCTGAACATAATAAAAATCCTAAACGTCCTGTG
TACCCTGAGTTCGATATTACGAATGAGGCTGCACACTTAGTTGAATCGGAATCAATTTCTAACTCCGATATAGCTATCAT
TATTACTGACCATAACGGCAAAATTATTTCCACCTCAGAACCCGTAACAAAAGATATGCAAAAACAACTTACTTGTAAAA
CAGAAACTGTCCCAGACGGCGGATTGGTCGTTGAAAGGAACTGGAAAAAATCAAAGTTCATCACAACAGTAAGCCCACTT
AACACAACAAAGTTTCAAGGAAAGCTATATATGTTATTAAAAACATCTTTCCTAGAAAATATGTTACTTAAACTCATGAA
CCAATTTCTTATCATTAGCGTTTTAACAATTATTTTAACAACAATTTCTGTCTTTGTTTTTTCACGCGTTATTACAGAAC
CACTTGTAAAAATGAAGAGAGCGACAGAAAAAATGTCAAAATTAAACAAGCCAATTCAATTAGGTATTAAACGAAATGAT
GAACTTGGAAGTTTAGCAAAAACAATTGAAGATTTATCGAGTGAACTTACGTATATGAAAAAAGAGCGCAATGAATTTCT
CGCTAGTGTCGCTCATGAACTATTAACTCCATTGACCTATATGAAAGGTTATGCGAAGGTAGCAAAGAGAGACTCTTTAA
CAAAAGAGGAGCGAGAAGAATACTTACAAATTATTGAGGATGAAACGGATAGTGTAACCGATCTCGTCCAAGATTTATTT
ATGCTTGTACAATTAGAACAACACCAATTTGTTATAAAAAAACAAAAAGTGCTTCTTCAGCCATTTTTAGAACGAATGGT
TGAAAAAACAAAAACAACATTAACAAATAAGCAAATGCAACTTCATGTATATTGCAAAGATGATTTAGAAGTTTGCATAG
ACGAAAGACGTATGGAACAAGTTATGTTAAATTTATTACACAACGCTTATCAACATTCGCCAGAAAACACATCCATTACG
ATACGTGTACTCATGGAAACAGATTCTTTTACAATAAGTGTACAAGATGAAGGTGAAGGTATTCCTGAAGAAGATATCCC
GCATATTTTTGACCGTTTTTATCGTGTTGATAAATCCAGAACACGAGCTACAGGCGGAAAAGGTATCGGGCTAGCTGTTG
CAAAGGAAATTGTAGAATTGCATAACGGTTCTATTCTAGTAACAAGCCAATTAGGAGCGGGAACAAACTTTATAATCGAG
CTACCTTTTGAATAA

Upstream 100 bases:

>100_bases
TCTATAAAGTCGGATATAAATGGAAAAGTGAATAATTACTTCGGTCAGTGGGAAATCGTATACCACTGACTCTTTATTAT
GAATAAGGTATGGTGAAAAA

Downstream 100 bases:

>100_bases
TATGCGTGTGAAAACACCAGTAGTAGTAAACACTACTGGTGTTATTTTGTTCATAAAAACAGTTCATATAAGCTAAGCTT
TTGAAATTATTCTTATTTCA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSKLSLKIGTYFLILALCIETIAFVSFYKSLSKMRIVEETDALLEKGNRYSKKIKSRERRDEYYKEMKHAEHNKNPKRPV
YPEFDITNEAAHLVESESISNSDIAIIITDHNGKIISTSEPVTKDMQKQLTCKTETVPDGGLVVERNWKKSKFITTVSPL
NTTKFQGKLYMLLKTSFLENMLLKLMNQFLIISVLTIILTTISVFVFSRVITEPLVKMKRATEKMSKLNKPIQLGIKRND
ELGSLAKTIEDLSSELTYMKKERNEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEEREEYLQIIEDETDSVTDLVQDLF
MLVQLEQHQFVIKKQKVLLQPFLERMVEKTKTTLTNKQMQLHVYCKDDLEVCIDERRMEQVMLNLLHNAYQHSPENTSIT
IRVLMETDSFTISVQDEGEGIPEEDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSQLGAGTNFIIE
LPFE

Sequences:

>Translated_484_residues
MSKLSLKIGTYFLILALCIETIAFVSFYKSLSKMRIVEETDALLEKGNRYSKKIKSRERRDEYYKEMKHAEHNKNPKRPV
YPEFDITNEAAHLVESESISNSDIAIIITDHNGKIISTSEPVTKDMQKQLTCKTETVPDGGLVVERNWKKSKFITTVSPL
NTTKFQGKLYMLLKTSFLENMLLKLMNQFLIISVLTIILTTISVFVFSRVITEPLVKMKRATEKMSKLNKPIQLGIKRND
ELGSLAKTIEDLSSELTYMKKERNEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEEREEYLQIIEDETDSVTDLVQDLF
MLVQLEQHQFVIKKQKVLLQPFLERMVEKTKTTLTNKQMQLHVYCKDDLEVCIDERRMEQVMLNLLHNAYQHSPENTSIT
IRVLMETDSFTISVQDEGEGIPEEDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSQLGAGTNFIIE
LPFE
>Mature_483_residues
SKLSLKIGTYFLILALCIETIAFVSFYKSLSKMRIVEETDALLEKGNRYSKKIKSRERRDEYYKEMKHAEHNKNPKRPVY
PEFDITNEAAHLVESESISNSDIAIIITDHNGKIISTSEPVTKDMQKQLTCKTETVPDGGLVVERNWKKSKFITTVSPLN
TTKFQGKLYMLLKTSFLENMLLKLMNQFLIISVLTIILTTISVFVFSRVITEPLVKMKRATEKMSKLNKPIQLGIKRNDE
LGSLAKTIEDLSSELTYMKKERNEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEEREEYLQIIEDETDSVTDLVQDLFM
LVQLEQHQFVIKKQKVLLQPFLERMVEKTKTTLTNKQMQLHVYCKDDLEVCIDERRMEQVMLNLLHNAYQHSPENTSITI
RVLMETDSFTISVQDEGEGIPEEDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSQLGAGTNFIIEL
PFE

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=34.9344978165939, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI1788393, Length=276, Percent_Identity=29.3478260869565, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786783, Length=337, Percent_Identity=27.0029673590504, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=24.4813278008299, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=30.9090909090909, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082128, Length=302, Percent_Identity=26.4900662251656, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1787894, Length=337, Percent_Identity=24.6290801186944, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1789149, Length=222, Percent_Identity=29.7297297297297, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1790861, Length=257, Percent_Identity=29.1828793774319, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790346, Length=301, Percent_Identity=24.2524916943522, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=28.4444444444444, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=29.7297297297297, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786912, Length=223, Percent_Identity=28.6995515695067, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788279, Length=289, Percent_Identity=24.2214532871972, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI87081816, Length=333, Percent_Identity=22.8228228228228, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788713, Length=230, Percent_Identity=24.7826086956522, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790551, Length=297, Percent_Identity=26.9360269360269, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790300, Length=231, Percent_Identity=29.004329004329, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789403, Length=373, Percent_Identity=22.7882037533512, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787374, Length=316, Percent_Identity=21.8354430379747, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55638; Mature: 55507

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLSLKIGTYFLILALCIETIAFVSFYKSLSKMRIVEETDALLEKGNRYSKKIKSRERR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DEYYKEMKHAEHNKNPKRPVYPEFDITNEAAHLVESESISNSDIAIIITDHNGKIISTSE
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCC
PVTKDMQKQLTCKTETVPDGGLVVERNWKKSKFITTVSPLNTTKFQGKLYMLLKTSFLEN
CHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCEECCEEEHHHHHHHHHH
MLLKLMNQFLIISVLTIILTTISVFVFSRVITEPLVKMKRATEKMSKLNKPIQLGIKRND
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
ELGSLAKTIEDLSSELTYMKKERNEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEEREE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YLQIIEDETDSVTDLVQDLFMLVQLEQHQFVIKKQKVLLQPFLERMVEKTKTTLTNKQMQ
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LHVYCKDDLEVCIDERRMEQVMLNLLHNAYQHSPENTSITIRVLMETDSFTISVQDEGEG
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCEEEEEECCCCC
IPEEDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSQLGAGTNFIIE
CCCCCHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEE
LPFE
CCCC
>Mature Secondary Structure 
SKLSLKIGTYFLILALCIETIAFVSFYKSLSKMRIVEETDALLEKGNRYSKKIKSRERR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
DEYYKEMKHAEHNKNPKRPVYPEFDITNEAAHLVESESISNSDIAIIITDHNGKIISTSE
HHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCC
PVTKDMQKQLTCKTETVPDGGLVVERNWKKSKFITTVSPLNTTKFQGKLYMLLKTSFLEN
CHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCCEECCEEEHHHHHHHHHH
MLLKLMNQFLIISVLTIILTTISVFVFSRVITEPLVKMKRATEKMSKLNKPIQLGIKRND
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCC
ELGSLAKTIEDLSSELTYMKKERNEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEEREE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
YLQIIEDETDSVTDLVQDLFMLVQLEQHQFVIKKQKVLLQPFLERMVEKTKTTLTNKQMQ
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LHVYCKDDLEVCIDERRMEQVMLNLLHNAYQHSPENTSITIRVLMETDSFTISVQDEGEG
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCEEEEEECCCCC
IPEEDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSQLGAGTNFIIE
CCCCCHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEE
LPFE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]