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The map label for this gene is ycbM [H]

Identifier: 218231682

GI number: 218231682

Start: 280821

End: 281435

Strand: Reverse

Name: ycbM [H]

Synonym: BCB4264_A0315

Alternate gene names: 218231682

Gene position: 281435-280821 (Counterclockwise)

Preceding gene: 218232857

Following gene: 218231539

Centisome position: 5.19

GC content: 35.77

Gene sequence:

>615_bases
TTGAAAGACGGAGTTGCTGCTTCTGAAATAGAAAAACAAGAATATCTTAAAATACTCTATATGAAATCAAATAACTTAAA
GCACCTAGTTGATGAAATATTCAATATGGCGAAGCTAGACGCTAATGAATTTCCACTAAAAGAAGAAGAACTCGACTTTT
CTGAAGTTACTAGAGAAGTTTTGATTGAATTTTTACCTGAGCTCTCAAAACATAACATCGAACTGCAAATTCTCATACCA
GAATCTACTTGTCCTATCATCGCAGATCATCTAAGCATTATGCGGATTATCGGTAATTTAATGAAAAATGCAATTTATTA
CGGAAAAGATGGGAAAACAATAGGAGTCGAATTGCTAGAAGCTGATGCAGAATACGAACTTCACATTTGGGATCAAGGCC
CTGGTATTCCAAAACATGATTTACAAAACGTATTTGAGCGAATGTACCGAAGCGAACAATCAAGAAACTCTTCATTTGGT
GGTAGCGGTCTCGGGCTTTCTATTTCCAAAGCGCTTGTTGAGAAAAACGGTGGACATATATGGGTTGAAAGTACTCCATG
GAAACGAACTACTTTTGGCTTTTCTATTCCAAAGCACAATACTTTTAAGAAATAG

Upstream 100 bases:

>100_bases
TGAAGCCAAAAGATCCGAGGAATCCAGAAAACAACTTTTGTCTAGTATCTCCCACGATATACGAACACCACTCACCTCCA
TTATCGGATATATAGATGCT

Downstream 100 bases:

>100_bases
TTAAGAAATGATTAATATGCAGTTAAGCCTTCCTTTTTATGATGTAAGTAAGAACTTATAGAAAGCAGGTGTCTCCTATA
AATACAATTATAAAAACGAC

Product: putative sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLKEEELDFSEVTREVLIEFLPELSKHNIELQILIP
ESTCPIIADHLSIMRIIGNLMKNAIYYGKDGKTIGVELLEADAEYELHIWDQGPGIPKHDLQNVFERMYRSEQSRNSSFG
GSGLGLSISKALVEKNGGHIWVESTPWKRTTFGFSIPKHNTFKK

Sequences:

>Translated_204_residues
MKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLKEEELDFSEVTREVLIEFLPELSKHNIELQILIP
ESTCPIIADHLSIMRIIGNLMKNAIYYGKDGKTIGVELLEADAEYELHIWDQGPGIPKHDLQNVFERMYRSEQSRNSSFG
GSGLGLSISKALVEKNGGHIWVESTPWKRTTFGFSIPKHNTFKK
>Mature_204_residues
MKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLKEEELDFSEVTREVLIEFLPELSKHNIELQILIP
ESTCPIIADHLSIMRIIGNLMKNAIYYGKDGKTIGVELLEADAEYELHIWDQGPGIPKHDLQNVFERMYRSEQSRNSSFG
GSGLGLSISKALVEKNGGHIWVESTPWKRTTFGFSIPKHNTFKK

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=191, Percent_Identity=26.1780104712042, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI1786912, Length=175, Percent_Identity=30.2857142857143, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789149, Length=191, Percent_Identity=30.3664921465969, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=192, Percent_Identity=28.125, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI145693157, Length=177, Percent_Identity=25.9887005649718, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1787894, Length=208, Percent_Identity=27.8846153846154, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=187, Percent_Identity=27.807486631016, Blast_Score=71, Evalue=4e-14,
Organism=Escherichia coli, GI1786783, Length=197, Percent_Identity=26.9035532994924, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1788713, Length=202, Percent_Identity=26.2376237623762, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=194, Percent_Identity=22.1649484536082, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=177, Percent_Identity=29.9435028248588, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1790346, Length=182, Percent_Identity=22.5274725274725, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 23296; Mature: 23296

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLKEEELDFSEVTREV
CCCCCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHH
LIEFLPELSKHNIELQILIPESTCPIIADHLSIMRIIGNLMKNAIYYGKDGKTIGVELLE
HHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEE
ADAEYELHIWDQGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHI
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEE
WVESTPWKRTTFGFSIPKHNTFKK
EEECCCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLKEEELDFSEVTREV
CCCCCCHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHH
LIEFLPELSKHNIELQILIPESTCPIIADHLSIMRIIGNLMKNAIYYGKDGKTIGVELLE
HHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEE
ADAEYELHIWDQGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHI
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEE
WVESTPWKRTTFGFSIPKHNTFKK
EEECCCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]