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The map label for this gene is ycbL [H]

Identifier: 218232857

GI number: 218232857

Start: 281824

End: 282537

Strand: Reverse

Name: ycbL [H]

Synonym: BCB4264_A0316

Alternate gene names: 218232857

Gene position: 282537-281824 (Counterclockwise)

Preceding gene: 218231858

Following gene: 218231682

Centisome position: 5.21

GC content: 32.07

Gene sequence:

>714_bases
ATGAAAGATATACGTATCCTTATAGCAGACGACGATAAAGAAATCCGAAATTTATTAAAAATATATTTAGAACGAGAATT
ATACATGGTAGACACTGCAATCAACGGCGAAGAAGCCTTACATTTATTTAATCAAAATAACTATAACCTCGTTATATTAG
ATCTTATGATGCCCAAAATAGATGGAATCGAGGTATGTAAAAAACTTAGAGATAAAACTAACATACCTATATTAATGCTC
ACCGCTAAAGATCACGAAGTTGATAAAATTTTAGGTTTAAGCATTGGTGCTGATGATTATATTACGAAACCTTTCAGCAT
TCACGAAGTAATTGCACGAGTAAAAGCTCTTATGCGGCGTTTTTTAGTTCTCGGAAGTAACAATACTGCTCAAGAAAAAA
CAACTTTATCTTTTAAAGGACTAACTATCAATTTAAATACATACACAGTTCATACAAACAAAGAAGAAATTAGCTTAACC
GGAAAAGAACTGGAACTGTTAAAATTCTTTACTTCAAACCCAGGGCAAGTATTTACAAAAACACAGCTCTTCCGAAATGT
GTGGGACGATAATTATATAGAAGATGATAATACCGTTATGGTACATATTCGAAAACTCAGAAAGAAAATAGAAATTGACC
CTTCCAATCCAAAATTCATTCAGACTATATGGGGAATTGGTTATAAGTTTGTAGGTGAAAAGCTTGAAGACTGA

Upstream 100 bases:

>100_bases
TTCCTCCAACAAAACTAGCAACCTTATTTTAACAAATACTAGTATATAATTAGAGAGTTGTTGTACTATCAATAAAACTC
TATTAGAAGCAGGTGAAGAT

Downstream 100 bases:

>100_bases
TAAAACCCTCTTCCTGATTTCATTACAACTTATCATTTGCGGGATTTTAAACATACAAATGGATCCAAGAATAAAAATGT
CTTTATTTATTATCCTTATC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAINGEEALHLFNQNNYNLVILDLMMPKIDGIEVCKKLRDKTNIPILML
TAKDHEVDKILGLSIGADDYITKPFSIHEVIARVKALMRRFLVLGSNNTAQEKTTLSFKGLTINLNTYTVHTNKEEISLT
GKELELLKFFTSNPGQVFTKTQLFRNVWDDNYIEDDNTVMVHIRKLRKKIEIDPSNPKFIQTIWGIGYKFVGEKLED

Sequences:

>Translated_237_residues
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAINGEEALHLFNQNNYNLVILDLMMPKIDGIEVCKKLRDKTNIPILML
TAKDHEVDKILGLSIGADDYITKPFSIHEVIARVKALMRRFLVLGSNNTAQEKTTLSFKGLTINLNTYTVHTNKEEISLT
GKELELLKFFTSNPGQVFTKTQLFRNVWDDNYIEDDNTVMVHIRKLRKKIEIDPSNPKFIQTIWGIGYKFVGEKLED
>Mature_237_residues
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAINGEEALHLFNQNNYNLVILDLMMPKIDGIEVCKKLRDKTNIPILML
TAKDHEVDKILGLSIGADDYITKPFSIHEVIARVKALMRRFLVLGSNNTAQEKTTLSFKGLTINLNTYTVHTNKEEISLT
GKELELLKFFTSNPGQVFTKTQLFRNVWDDNYIEDDNTVMVHIRKLRKKIEIDPSNPKFIQTIWGIGYKFVGEKLED

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=38.1578947368421, Blast_Score=188, Evalue=2e-49,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=37.1681415929204, Blast_Score=163, Evalue=9e-42,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=36.6812227074236, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=35.9307359307359, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1790863, Length=241, Percent_Identity=36.5145228215768, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=36.283185840708, Blast_Score=153, Evalue=8e-39,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=35.3982300884956, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=35.5263157894737, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=32.8947368421053, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=34.3478260869565, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=30.2222222222222, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789402, Length=234, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=31.7796610169492, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=35.5140186915888, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=40, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788191, Length=112, Percent_Identity=33.9285714285714, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27462; Mature: 27462

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAINGEEALHLFNQNNYNLVILDLMMPKI
CCCEEEEEECCCHHHHHHHHHHHHCEEEEEEEECCCHHHEEEECCCCCCEEEEEEECCCC
DGIEVCKKLRDKTNIPILMLTAKDHEVDKILGLSIGADDYITKPFSIHEVIARVKALMRR
CHHHHHHHHHHCCCCCEEEEEECCCCHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
FLVLGSNNTAQEKTTLSFKGLTINLNTYTVHTNKEEISLTGKELELLKFFTSNPGQVFTK
HEEECCCCCCCCEEEEEEEEEEEEEEEEEEECCCCEEEECCCCEEEHHHHHCCCCCCHHH
TQLFRNVWDDNYIEDDNTVMVHIRKLRKKIEIDPSNPKFIQTIWGIGYKFVGEKLED
HHHHHHHCCCCCCCCCCEEEEEEHHHHHHEECCCCCCHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MKDIRILIADDDKEIRNLLKIYLERELYMVDTAINGEEALHLFNQNNYNLVILDLMMPKI
CCCEEEEEECCCHHHHHHHHHHHHCEEEEEEEECCCHHHEEEECCCCCCEEEEEEECCCC
DGIEVCKKLRDKTNIPILMLTAKDHEVDKILGLSIGADDYITKPFSIHEVIARVKALMRR
CHHHHHHHHHHCCCCCEEEEEECCCCHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
FLVLGSNNTAQEKTTLSFKGLTINLNTYTVHTNKEEISLTGKELELLKFFTSNPGQVFTK
HEEECCCCCCCCEEEEEEEEEEEEEEEEEEECCCCEEEECCCCEEEHHHHHCCCCCCHHH
TQLFRNVWDDNYIEDDNTVMVHIRKLRKKIEIDPSNPKFIQTIWGIGYKFVGEKLED
HHHHHHHCCCCCCCCCCEEEEEEHHHHHHEECCCCCCHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]