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The map label for this gene is 212224525

Identifier: 212224525

GI number: 212224525

Start: 1242868

End: 1243653

Strand: Reverse

Name: 212224525

Synonym: TON_1374

Alternate gene names: NA

Gene position: 1243653-1242868 (Counterclockwise)

Preceding gene: 212224528

Following gene: 212224523

Centisome position: 67.31

GC content: 52.42

Gene sequence:

>786_bases
ATGGTGAAAATACCCAAGAGCCATCCACGCTACTGGAGCCTCTACTATAGAGAGAAGATCATCGAGGGAATGGAGAAGGG
AATGACGGCGAAGGCCGGCTTGATCGCCCACGGTAGGGGAGAGGCCTTCGACTATCTCATCGGCGAAAGGACGATAGAAC
CTGCTGAGAGGGCCATGAGAGCAGCGGTCGCGAAGCTCCTCCTTGCGGAGAATCCCGTTGTCTCTGTGAACGGCAACGTT
GCCGCTTTGGTGCCGAAGGAGACAATAGAGCTCGCCAGAGCACTCAATGCCAAACTCGAGATAAACCTCTTCTATCGCAC
GGAGGATCGTGTTAAAGCGATAGCAGAAGAACTCCGCAAATACGATCCCGAGATAGAGCTCCTCGGTATAAACCCAACAA
AGAGGATTCCCGGCCTAGAGCACGAGCGCGGAAAAGTCGATGAGAATGGCATCTGGAAGGCCGACGTGGTAGTCGTTCCT
CTGGAGGACGGTGACAGGACCGAGGCCCTCGTTAGGATGGGCAAATTTGTGATAACCATTGATTTGAACCCATTATCTCG
TTCAGCGAGGATGGCAGATATAACCATCGTAGACAACATCGTCAGGGCTTATCCGAGGATGACAGAGCTCGCTCGTGAAA
TGAAGGACTACAGCAGGGGGGAGCTCATCAGAATTATCGAGGAGTATGACAATGGAAAAACGCTGAACGACGTACTTCTC
CACATAAGGGACAGACTAACTAAGCTCGCGGAAGGTGGGATATGGCGGAAGAAGCAGCTCGATTAG

Upstream 100 bases:

>100_bases
AAAAAGTTCTCTGCAGGCTTTATTAGGGACGGCTAAAAGGATAAATCCTGCTGGGAAGGCTTTTTATCATATCATGCCAA
ACCAATACAAGGTGATGTAA

Downstream 100 bases:

>100_bases
AGTTTGCCCATTAGAGCTCCATCTCTGTCTTTTCTACAAGTCTTCTCAGCCCCGTTATAAGTTCTGCCTCACTTCCCGCG
TGGGAAATCACCAGTGGGAC

Product: protein

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MVKIPKSHPRYWSLYYREKIIEGMEKGMTAKAGLIAHGRGEAFDYLIGERTIEPAERAMRAAVAKLLLAENPVVSVNGNV
AALVPKETIELARALNAKLEINLFYRTEDRVKAIAEELRKYDPEIELLGINPTKRIPGLEHERGKVDENGIWKADVVVVP
LEDGDRTEALVRMGKFVITIDLNPLSRSARMADITIVDNIVRAYPRMTELAREMKDYSRGELIRIIEEYDNGKTLNDVLL
HIRDRLTKLAEGGIWRKKQLD

Sequences:

>Translated_261_residues
MVKIPKSHPRYWSLYYREKIIEGMEKGMTAKAGLIAHGRGEAFDYLIGERTIEPAERAMRAAVAKLLLAENPVVSVNGNV
AALVPKETIELARALNAKLEINLFYRTEDRVKAIAEELRKYDPEIELLGINPTKRIPGLEHERGKVDENGIWKADVVVVP
LEDGDRTEALVRMGKFVITIDLNPLSRSARMADITIVDNIVRAYPRMTELAREMKDYSRGELIRIIEEYDNGKTLNDVLL
HIRDRLTKLAEGGIWRKKQLD
>Mature_261_residues
MVKIPKSHPRYWSLYYREKIIEGMEKGMTAKAGLIAHGRGEAFDYLIGERTIEPAERAMRAAVAKLLLAENPVVSVNGNV
AALVPKETIELARALNAKLEINLFYRTEDRVKAIAEELRKYDPEIELLGINPTKRIPGLEHERGKVDENGIWKADVVVVP
LEDGDRTEALVRMGKFVITIDLNPLSRSARMADITIVDNIVRAYPRMTELAREMKDYSRGELIRIIEEYDNGKTLNDVLL
HIRDRLTKLAEGGIWRKKQLD

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent and ADP-producing reaction [H]

COG id: COG1701

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal pantothenate synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002855
- ProDom:   PD016827 [H]

Pfam domain/function: PF02006 DUF137 [H]

EC number: NA

Molecular weight: Translated: 29686; Mature: 29686

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIPKSHPRYWSLYYREKIIEGMEKGMTAKAGLIAHGRGEAFDYLIGERTIEPAERAMR
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHCCCCCCHHHHHHH
AAVAKLLLAENPVVSVNGNVAALVPKETIELARALNAKLEINLFYRTEDRVKAIAEELRK
HHHHHHHHHCCCEEEECCCEEEECCHHHHHHHHHCCCEEEEEEEEECHHHHHHHHHHHHH
YDPEIELLGINPTKRIPGLEHERGKVDENGIWKADVVVVPLEDGDRTEALVRMGKFVITI
CCCCEEEEECCCHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHCCEEEEE
DLNPLSRSARMADITIVDNIVRAYPRMTELAREMKDYSRGELIRIIEEYDNGKTLNDVLL
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
HIRDRLTKLAEGGIWRKKQLD
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVKIPKSHPRYWSLYYREKIIEGMEKGMTAKAGLIAHGRGEAFDYLIGERTIEPAERAMR
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHCCCCCCHHHHHHH
AAVAKLLLAENPVVSVNGNVAALVPKETIELARALNAKLEINLFYRTEDRVKAIAEELRK
HHHHHHHHHCCCEEEECCCEEEECCHHHHHHHHHCCCEEEEEEEEECHHHHHHHHHHHHH
YDPEIELLGINPTKRIPGLEHERGKVDENGIWKADVVVVPLEDGDRTEALVRMGKFVITI
CCCCEEEEECCCHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHCCEEEEE
DLNPLSRSARMADITIVDNIVRAYPRMTELAREMKDYSRGELIRIIEEYDNGKTLNDVLL
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHH
HIRDRLTKLAEGGIWRKKQLD
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]