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The map label for this gene is ribB [H]

Identifier: 209551972

GI number: 209551972

Start: 36535

End: 37179

Strand: Reverse

Name: ribB [H]

Synonym: Rleg2_6109

Alternate gene names: 209551972

Gene position: 37179-36535 (Counterclockwise)

Preceding gene: 209551973

Following gene: 209551971

Centisome position: 12.04

GC content: 57.52

Gene sequence:

>645_bases
ATGAGTTTTTCCACGATCGAGCAAGCGATAGTCGCTCTCCGGCGCGGCGAAATCATAGTGGTCGTAGACGACAAGGACAG
GGAGAACGAAGGCGATGTACTGGTTGCGTCCGACCTTGTAACCGCTGAGACCATAGCCTTTATGATGAGCCACGCGCGCG
GGCTGATTTGTGTGGCAATGGAGGGAAGCAGATTGGATACGCTGGAAATTCCCTTGATGGTCTCAAGTAACAGCGACTCC
TTCAAAACGGCGTTTACAGTTTCCGTTGATTACATCCCCGAGACCACAACCGGCATCAGCGCAGCAGATCGCGCTGCCAC
TATCCGCGCGCTCCTGGACGTAAGCGCCAGTCCTCAAAGCTTCGCCCGGCCAGGACATATATTTCCGTTGCGCGCACATC
CGGCGGGGGTTCTGGCGCGGCCTGGTCATACGGAGGCGGCGGTCGACCTCACTAAATTGGCCGGCCTCACGCCATCCGGC
GTCATCTGCGAAGTCGCCAACGATGATGGTACCATGGCGCGACTGCCTCAGCTCGAGCTGTTTGCCAAACGTCACGGCCT
TATCCTGATCACGATCGAGGACCTTATCGCCTTCCGAACTGAGCACCAGCTCTCGAATAGAGAAGTGCTGCGTTCCGTCG
CCTAG

Upstream 100 bases:

>100_bases
GCGCTAGCCGGAACTTGATCGTAGCGAGTTCTGGGACCCATACCGGCACACAGCCGAAAGCGAATTTTAGCAGGGAACCG
CCAATGCGGGGGAGAGAGAC

Downstream 100 bases:

>100_bases
CGCCCGATCTCCCATTTCACGTCAGAAGGTTCCGCATTGGAGAGAATGAGCTCACTATGTCCATCACCACAATGCTATTT
GTTCCCGCAGACCGTCCCGA

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MSFSTIEQAIVALRRGEIIVVVDDKDRENEGDVLVASDLVTAETIAFMMSHARGLICVAMEGSRLDTLEIPLMVSSNSDS
FKTAFTVSVDYIPETTTGISAADRAATIRALLDVSASPQSFARPGHIFPLRAHPAGVLARPGHTEAAVDLTKLAGLTPSG
VICEVANDDGTMARLPQLELFAKRHGLILITIEDLIAFRTEHQLSNREVLRSVA

Sequences:

>Translated_214_residues
MSFSTIEQAIVALRRGEIIVVVDDKDRENEGDVLVASDLVTAETIAFMMSHARGLICVAMEGSRLDTLEIPLMVSSNSDS
FKTAFTVSVDYIPETTTGISAADRAATIRALLDVSASPQSFARPGHIFPLRAHPAGVLARPGHTEAAVDLTKLAGLTPSG
VICEVANDDGTMARLPQLELFAKRHGLILITIEDLIAFRTEHQLSNREVLRSVA
>Mature_213_residues
SFSTIEQAIVALRRGEIIVVVDDKDRENEGDVLVASDLVTAETIAFMMSHARGLICVAMEGSRLDTLEIPLMVSSNSDSF
KTAFTVSVDYIPETTTGISAADRAATIRALLDVSASPQSFARPGHIFPLRAHPAGVLARPGHTEAAVDLTKLAGLTPSGV
ICEVANDDGTMARLPQLELFAKRHGLILITIEDLIAFRTEHQLSNREVLRSVA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=201, Percent_Identity=47.2636815920398, Blast_Score=216, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=47.5490196078431, Blast_Score=194, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422 [H]

Pfam domain/function: PF00926 DHBP_synthase [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 23008; Mature: 22876

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSTIEQAIVALRRGEIIVVVDDKDRENEGDVLVASDLVTAETIAFMMSHARGLICVAM
CCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCEEEEEE
EGSRLDTLEIPLMVSSNSDSFKTAFTVSVDYIPETTTGISAADRAATIRALLDVSASPQS
CCCCCCEEEEEEEEECCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHH
FARPGHIFPLRAHPAGVLARPGHTEAAVDLTKLAGLTPSGVICEVANDDGTMARLPQLEL
HCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCEECCCHHHH
FAKRHGLILITIEDLIAFRTEHQLSNREVLRSVA
HHHHCCEEEEEHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
SFSTIEQAIVALRRGEIIVVVDDKDRENEGDVLVASDLVTAETIAFMMSHARGLICVAM
CHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCEEEEEE
EGSRLDTLEIPLMVSSNSDSFKTAFTVSVDYIPETTTGISAADRAATIRALLDVSASPQS
CCCCCCEEEEEEEEECCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHH
FARPGHIFPLRAHPAGVLARPGHTEAAVDLTKLAGLTPSGVICEVANDDGTMARLPQLEL
HCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCEECCCHHHH
FAKRHGLILITIEDLIAFRTEHQLSNREVLRSVA
HHHHCCEEEEEHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]