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The map label for this gene is nodT [H]

Identifier: 209550733

GI number: 209550733

Start: 3239510

End: 3240952

Strand: Direct

Name: nodT [H]

Synonym: Rleg2_3157

Alternate gene names: 209550733

Gene position: 3239510-3240952 (Clockwise)

Preceding gene: 209550732

Following gene: 209550734

Centisome position: 71.39

GC content: 63.41

Gene sequence:

>1443_bases
ATGGTATCTCTTCGTTTTGCCGCCACACCGGCATTGCTGTTATTATTGTCGGGCTGCGTTGTTGGCCCGGATCATGTTCC
TCCTGAGATGCCGCTGCCCGCCAAATTCGGAGAGGGCGGAACGAAGAGTGTAGGCGATGTTGCTACCGCCGCCTGGTGGA
CCGCCTTCAACGACCCCAAACTGAATGGCTATGTCAAAGCCGGCCTCGATCAGAACCTGACTGTCCAGCAGGCGATCGAG
CGCATCAATGCGGCCTCCGCCAACGTCACCACCGCCGGCGCCGGCGCCCTGCCGAACCTGACGGTCGGCGGCTCACACAC
GGTCAGCGGCCAGAGAGGCGAGCTGCGCACGCAGTTCGACACGCGCAACACCAGTGCCGGCGAAGTCCAGCTGAGCTGGC
TGCTCGATCTCTTCGGCCTCTATAAGCGCAGCACCGAGAGCGCGCTTGCTTCGCTCGATTCGGCCTACGCCTCCGCTGAT
GTCGCCAAGCTGACCCTGGTGCAGGATCTGGTCTCGAGCTATATCGACGTTCGCTACTATCAGCAGCGCCTGGCGCTTTC
GAGGGCCAACCTGAAGTCGCGTCAGGAAACCTACGAGCTTACCAAATTCCAGCTTGAAGCCGGCGCAGCCTCGCGTCTTG
ACGTCGTCCAGGCCGAAGGCCTGGTACAATCGACGCTCGCCGAAATTCCCGGCCTCGAAACCAACATCCGCATATCGGCC
CATCACATTGCCACCTTGCTCGGCCTGCCGGCCTCGGCCCTCGTCGACGAATTGCTGAAGGGTCATGGACAGCCCGTATT
CCGCGGCGGCATCAACTCCGGCATCCCTGCAGACCTGATCCGCAACCGTCCCGACGTTCGCGTCGCGGAGCGCGATCTCG
CCGCCGCAACGGCCAATATCGGTGTAGCCCAGGCGCAGCTTTATCCGAGCATCTCGCTCAGCGGTTCGATCTCGCCGTCC
TACATCAACCAGCGCGGCATCCATGGCGGCCTGACGCCTTGGTCCTTCGGTCCGACCCTCAACCTGCCGATCTTCGATGG
CGGCCGCCTGCGCGCCAACGTCAAGTCTGCACAGTCCGACGCCGCGACCGCCTACCTCAACTGGAAATCGACGGTGCTGA
CCTCCGTCGAGCAGGTTGAGAACGCGCTCGCCGCTGTCCGGCGTGACGCCCGCACGGTCTCGGCACTCCAGGCGCAGGTG
AAGACCACGCAGGAAACCCTCGAACTGTCGACTGCATCTTACAAGGACGGCGCCTCTTCGTTGCTCGACGTTCTCGACGC
GCAGCGCCAGGTTTCGCTCGCCCAGGCAAGCCTTGCCCAGGCAGTTCAGCAGATGGCCAAGGACTATGTCTCCCTCAACA
TCGCGGTCGGCGGCGGCTATGCCCCCGGCGGCAAGACGACCGTGGCCAACACCACTGTCGCGGTGAAGCCGGCCAAGACC
TGA

Upstream 100 bases:

>100_bases
TGCTTCGGAATGGTGTTTTGGGTAAACGAGGCGCGGCGGCCGATAGTGAAGCATGAAGCTTCGGACAAGAATTGACTTGC
TCGAGTACAGGATGAAATGA

Downstream 100 bases:

>100_bases
TCGGCTGCCTTGCGCCGTCTGGACATATAGAGCCCCGCGATCGTCTCGCGGGGCTTTTTCATGTCGGCCGAGTTTGTATC
GCGGATAATGCGCGATAAGA

Product: RND efflux system, outer membrane lipoprotein, NodT family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MVSLRFAATPALLLLLSGCVVGPDHVPPEMPLPAKFGEGGTKSVGDVATAAWWTAFNDPKLNGYVKAGLDQNLTVQQAIE
RINAASANVTTAGAGALPNLTVGGSHTVSGQRGELRTQFDTRNTSAGEVQLSWLLDLFGLYKRSTESALASLDSAYASAD
VAKLTLVQDLVSSYIDVRYYQQRLALSRANLKSRQETYELTKFQLEAGAASRLDVVQAEGLVQSTLAEIPGLETNIRISA
HHIATLLGLPASALVDELLKGHGQPVFRGGINSGIPADLIRNRPDVRVAERDLAAATANIGVAQAQLYPSISLSGSISPS
YINQRGIHGGLTPWSFGPTLNLPIFDGGRLRANVKSAQSDAATAYLNWKSTVLTSVEQVENALAAVRRDARTVSALQAQV
KTTQETLELSTASYKDGASSLLDVLDAQRQVSLAQASLAQAVQQMAKDYVSLNIAVGGGYAPGGKTTVANTTVAVKPAKT

Sequences:

>Translated_480_residues
MVSLRFAATPALLLLLSGCVVGPDHVPPEMPLPAKFGEGGTKSVGDVATAAWWTAFNDPKLNGYVKAGLDQNLTVQQAIE
RINAASANVTTAGAGALPNLTVGGSHTVSGQRGELRTQFDTRNTSAGEVQLSWLLDLFGLYKRSTESALASLDSAYASAD
VAKLTLVQDLVSSYIDVRYYQQRLALSRANLKSRQETYELTKFQLEAGAASRLDVVQAEGLVQSTLAEIPGLETNIRISA
HHIATLLGLPASALVDELLKGHGQPVFRGGINSGIPADLIRNRPDVRVAERDLAAATANIGVAQAQLYPSISLSGSISPS
YINQRGIHGGLTPWSFGPTLNLPIFDGGRLRANVKSAQSDAATAYLNWKSTVLTSVEQVENALAAVRRDARTVSALQAQV
KTTQETLELSTASYKDGASSLLDVLDAQRQVSLAQASLAQAVQQMAKDYVSLNIAVGGGYAPGGKTTVANTTVAVKPAKT
>Mature_480_residues
MVSLRFAATPALLLLLSGCVVGPDHVPPEMPLPAKFGEGGTKSVGDVATAAWWTAFNDPKLNGYVKAGLDQNLTVQQAIE
RINAASANVTTAGAGALPNLTVGGSHTVSGQRGELRTQFDTRNTSAGEVQLSWLLDLFGLYKRSTESALASLDSAYASAD
VAKLTLVQDLVSSYIDVRYYQQRLALSRANLKSRQETYELTKFQLEAGAASRLDVVQAEGLVQSTLAEIPGLETNIRISA
HHIATLLGLPASALVDELLKGHGQPVFRGGINSGIPADLIRNRPDVRVAERDLAAATANIGVAQAQLYPSISLSGSISPS
YINQRGIHGGLTPWSFGPTLNLPIFDGGRLRANVKSAQSDAATAYLNWKSTVLTSVEQVENALAAVRRDARTVSALQAQV
KTTQETLELSTASYKDGASSLLDVLDAQRQVSLAQASLAQAVQQMAKDYVSLNIAVGGGYAPGGKTTVANTTVAVKPAKT

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=456, Percent_Identity=28.5087719298246, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI2367348, Length=482, Percent_Identity=22.4066390041494, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50575; Mature: 50575

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSLRFAATPALLLLLSGCVVGPDHVPPEMPLPAKFGEGGTKSVGDVATAAWWTAFNDPK
CEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
LNGYVKAGLDQNLTVQQAIERINAASANVTTAGAGALPNLTVGGSHTVSGQRGELRTQFD
CCCEEECCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCEECCCCCCCCCCCCCCEEEEC
TRNTSAGEVQLSWLLDLFGLYKRSTESALASLDSAYASADVAKLTLVQDLVSSYIDVRYY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQRLALSRANLKSRQETYELTKFQLEAGAASRLDVVQAEGLVQSTLAEIPGLETNIRISA
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHH
HHIATLLGLPASALVDELLKGHGQPVFRGGINSGIPADLIRNRPDVRVAERDLAAATANI
HHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHCCCCCCEEHHHHHHHHHHCC
GVAQAQLYPSISLSGSISPSYINQRGIHGGLTPWSFGPTLNLPIFDGGRLRANVKSAQSD
CHHHHHHCCCEEECCCCCHHHHHHCCCCCCCCCCCCCCEECCEECCCCCEEECHHHCCCC
AATAYLNWKSTVLTSVEQVENALAAVRRDARTVSALQAQVKTTQETLELSTASYKDGASS
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LLDVLDAQRQVSLAQASLAQAVQQMAKDYVSLNIAVGGGYAPGGKTTVANTTVAVKPAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEECEEEEEECCCC
>Mature Secondary Structure
MVSLRFAATPALLLLLSGCVVGPDHVPPEMPLPAKFGEGGTKSVGDVATAAWWTAFNDPK
CEEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCC
LNGYVKAGLDQNLTVQQAIERINAASANVTTAGAGALPNLTVGGSHTVSGQRGELRTQFD
CCCEEECCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCEECCCCCCCCCCCCCCEEEEC
TRNTSAGEVQLSWLLDLFGLYKRSTESALASLDSAYASADVAKLTLVQDLVSSYIDVRYY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQRLALSRANLKSRQETYELTKFQLEAGAASRLDVVQAEGLVQSTLAEIPGLETNIRISA
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHH
HHIATLLGLPASALVDELLKGHGQPVFRGGINSGIPADLIRNRPDVRVAERDLAAATANI
HHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHCCCCCCEEHHHHHHHHHHCC
GVAQAQLYPSISLSGSISPSYINQRGIHGGLTPWSFGPTLNLPIFDGGRLRANVKSAQSD
CHHHHHHCCCEEECCCCCHHHHHHCCCCCCCCCCCCCCEECCEECCCCCEEECHHHCCCC
AATAYLNWKSTVLTSVEQVENALAAVRRDARTVSALQAQVKTTQETLELSTASYKDGASS
CEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LLDVLDAQRQVSLAQASLAQAVQQMAKDYVSLNIAVGGGYAPGGKTTVANTTVAVKPAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEECEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2338917; 2622339 [H]