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The map label for this gene is purC2 [H]

Identifier: 209550729

GI number: 209550729

Start: 3233183

End: 3234127

Strand: Direct

Name: purC2 [H]

Synonym: Rleg2_3153

Alternate gene names: 209550729

Gene position: 3233183-3234127 (Clockwise)

Preceding gene: 209550728

Following gene: 209550730

Centisome position: 71.25

GC content: 61.06

Gene sequence:

>945_bases
GTGCGAATTCTCTCCGAAGCCCATTTCCCGGAACTGCCGAACTATTATCGCGGCAAGGTGCGCGAGAATTACGATCTTCC
GGACGGACGCCGCATCATCATCAGCACCGACCGGCTGAGCGCTTTCGACCGCATCCTCACCTGCATTCCTTATAAGGGCC
AGGTGCTGACGCAGACCGCGCGCTATTGGTTCGAGGCGACGAAGGACATCTGCCCGAACCATGTCCTCGACTATCCTGAT
GCGAATGTCGTGATCGGCAAGCGGCTCGACATCCTGCCGGTCGAAATCGTCGTGCGCGGTTATCTCGCCGGCACCACCGG
CACATCGATCCTGACGCTCTATAAGAAGGGTGAACGCGAGATGTACGGCATGCGCCTGCCGGACGGCATGCGCGACAACC
AGATCCTGCCGGAGCCGGTCATCACCCCGACCAGCAAGGAATTCGACGGCGGCCATGACGAGCCGCTGACGCCTGCCGAA
ATCGTCAGCCGCGGCCTTCTGACCAAGGAGCAGTGGGAAACCCTGTCGCGATATGCGCTCGCCCTTTTTGCCCGCGGCCA
GGAGATGGCTGCCAAACGCGGGCTGATCCTCGTCGACACCAAATATGAATTCGGCACCGACGGCGACGGCAACATCATCC
TCGCCGACGAGATCCATACGCCCGACAGCAGCCGCTACTGGCTTGCCGAAAGCTATCCGGCCAGTTTTGCCGCCGGAAAA
CGTCCGGAAAGTTTCGACAAGGATTTCGTCCGCGCCTGGGTGGCGGAACGCTGCGACCCATATAAGGATGAGATCCCCGA
GATCCCCACCGAACTGATCGAACAGACCTCGGCCGTCTATATCAGGGCCTATGAGGCGATCACCGGCGAGCGCTTTGTTC
CCGACGATAGCGGCGAGACACCGCTTGCCCGCATCCGGCAGAACCTCGCCCCCCACTTCTCCTGA

Upstream 100 bases:

>100_bases
TGTTCTGGCTGTGATGCGATACTTGGCATCTGACTTGACTTCCCCCGCGATGAAACTAGAGCAGGAAGCCTTCACCCAAT
TACAAGGACAGTCGAGCGCC

Downstream 100 bases:

>100_bases
GATGGCAGCGCGCGGAAGCCTCCGGCCAATCATCGGCTTGCGGCATTTCGTGCAATCGCGCTAACATCAGCCAAAAGGAT
CGGGCCCGGCCCGGCGGGGG

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase 2 [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MRILSEAHFPELPNYYRGKVRENYDLPDGRRIIISTDRLSAFDRILTCIPYKGQVLTQTARYWFEATKDICPNHVLDYPD
ANVVIGKRLDILPVEIVVRGYLAGTTGTSILTLYKKGEREMYGMRLPDGMRDNQILPEPVITPTSKEFDGGHDEPLTPAE
IVSRGLLTKEQWETLSRYALALFARGQEMAAKRGLILVDTKYEFGTDGDGNIILADEIHTPDSSRYWLAESYPASFAAGK
RPESFDKDFVRAWVAERCDPYKDEIPEIPTELIEQTSAVYIRAYEAITGERFVPDDSGETPLARIRQNLAPHFS

Sequences:

>Translated_314_residues
MRILSEAHFPELPNYYRGKVRENYDLPDGRRIIISTDRLSAFDRILTCIPYKGQVLTQTARYWFEATKDICPNHVLDYPD
ANVVIGKRLDILPVEIVVRGYLAGTTGTSILTLYKKGEREMYGMRLPDGMRDNQILPEPVITPTSKEFDGGHDEPLTPAE
IVSRGLLTKEQWETLSRYALALFARGQEMAAKRGLILVDTKYEFGTDGDGNIILADEIHTPDSSRYWLAESYPASFAAGK
RPESFDKDFVRAWVAERCDPYKDEIPEIPTELIEQTSAVYIRAYEAITGERFVPDDSGETPLARIRQNLAPHFS
>Mature_314_residues
MRILSEAHFPELPNYYRGKVRENYDLPDGRRIIISTDRLSAFDRILTCIPYKGQVLTQTARYWFEATKDICPNHVLDYPD
ANVVIGKRLDILPVEIVVRGYLAGTTGTSILTLYKKGEREMYGMRLPDGMRDNQILPEPVITPTSKEFDGGHDEPLTPAE
IVSRGLLTKEQWETLSRYALALFARGQEMAAKRGLILVDTKYEFGTDGDGNIILADEIHTPDSSRYWLAESYPASFAAGK
RPESFDKDFVRAWVAERCDPYKDEIPEIPTELIEQTSAVYIRAYEAITGERFVPDDSGETPLARIRQNLAPHFS

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=307, Percent_Identity=32.8990228013029, Blast_Score=175, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 35643; Mature: 35643

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01057 SAICAR_SYNTHETASE_1 ; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILSEAHFPELPNYYRGKVRENYDLPDGRRIIISTDRLSAFDRILTCIPYKGQVLTQTA
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCCCHHHHHHH
RYWFEATKDICPNHVLDYPDANVVIGKRLDILPVEIVVRGYLAGTTGTSILTLYKKGERE
HHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHCCCCCCEEEEEEECCCHH
MYGMRLPDGMRDNQILPEPVITPTSKEFDGGHDEPLTPAEIVSRGLLTKEQWETLSRYAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHH
ALFARGQEMAAKRGLILVDTKYEFGTDGDGNIILADEIHTPDSSRYWLAESYPASFAAGK
HHHHCCHHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCHHHCCC
RPESFDKDFVRAWVAERCDPYKDEIPEIPTELIEQTSAVYIRAYEAITGERFVPDDSGET
CCCHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHEEEEEEEHHCCCCCCCCCCCCC
PLARIRQNLAPHFS
HHHHHHHHCCCCCC
>Mature Secondary Structure
MRILSEAHFPELPNYYRGKVRENYDLPDGRRIIISTDRLSAFDRILTCIPYKGQVLTQTA
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHCCCCCHHHHHHH
RYWFEATKDICPNHVLDYPDANVVIGKRLDILPVEIVVRGYLAGTTGTSILTLYKKGERE
HHHHHHHHHCCCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHCCCCCCEEEEEEECCCHH
MYGMRLPDGMRDNQILPEPVITPTSKEFDGGHDEPLTPAEIVSRGLLTKEQWETLSRYAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHH
ALFARGQEMAAKRGLILVDTKYEFGTDGDGNIILADEIHTPDSSRYWLAESYPASFAAGK
HHHHCCHHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCCHHHCCC
RPESFDKDFVRAWVAERCDPYKDEIPEIPTELIEQTSAVYIRAYEAITGERFVPDDSGET
CCCHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHEEEEEEEHHCCCCCCCCCCCCC
PLARIRQNLAPHFS
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]