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The map label for this gene is glnII [H]

Identifier: 209550421

GI number: 209550421

Start: 2891895

End: 2892935

Strand: Direct

Name: glnII [H]

Synonym: Rleg2_2842

Alternate gene names: 209550421

Gene position: 2891895-2892935 (Clockwise)

Preceding gene: 209550419

Following gene: 209550422

Centisome position: 63.73

GC content: 59.17

Gene sequence:

>1041_bases
ATGACAAAATATAAGCTCGAGTATATTTGGCTCGATGGGTACACTCCGGTACCGAACCTGCGTGGCAAGACGCAGATCAA
GGAATTCGACGTATTCCCGACGCTGGAACAGCTTCCGCTCTGGGGCTTTGACGGTTCGTCGACCATGCAGGCCGAAGGCC
GCAGCTCCGATTGCGTGCTGAAGCCGGTCGCAATCTATCCCGACCCGGCCCGCACCAATGGCGCGCTCGTCATGTGCGAA
GTCATGATGCCCGATGGCGTCACGCCGCACCCGAGCAATGCCCGCGCCACCATCCTCGACGACGAAGACGCCTGGTTCGG
CTTCGAGCAGGAATATTTCTTCTATCAGAACGGTCGTCCGCTCGGCTTCCCTGAGCAGGGTTATCCGGCTCCGCAGGGCC
CCTACTACACCGGCGTCGGTTATTCGAACGTCGGCGATGTCGCCCGCGAAATCGTCGAAGAGCATCTCGACCTCTGCCTC
GCTGCCGGCATCAACCACGAAGGTATTAATGCCGAAGTGGCCAAGGGCCAGTGGGAATTCCAGATTTTCGGCAAGGGCTC
CAAGAAGGCCGCCGACCAGATCTGGATGGCACGCTATCTGCTGCAGCGCCTGACCGAAAAATACGGCATCGACATCGAGT
ATCATTGCAAGCCGCTCGGCGACACCGACTGGAACGGCTCGGGCATGCATTGCAACTTCTCGACCAAGTACATGCGCGAA
GTCGGCGGCAAGGCCTATTTCGAGGCGCTGATGGCGCAGTTCGAAAAGAACCTGATGGACCACATCGAAGTCTACGGTCC
TGACAACGACAAGCGCCTGACCGGCAAGCACGAAACCGCACCGTGGAACAAGTTCTCCTACGGCGTTGCCGACCGTGGCG
CCTCCATCCGCGTCCCGCACTCCTTCGTCAAAAACGACTACAAGGGCTATCTGGAAGATCGCCGCCCGAACTCGCAGGGC
TGCCCCTACCAGATCGCTTCGCAGGTTCTGAAGACGATTTCGGAAGTTCCGACTGCAAGCTCGGCTTCCGCTGCCGCTTA
A

Upstream 100 bases:

>100_bases
GCTACGTGCTTTTAAAGGTGCATCCCCTGGCGGTTGGGTGCGCTTGCGCGCCCAGATCGTCTCCGGATTTGCTCACCTTC
GTAGCATTGAGAGAGTCACG

Downstream 100 bases:

>100_bases
CCTCCCAAATGGCGCCGGTCGACGACCGGCGCCGTCCTTCTTTCCGCATGCAAACCCGCGATCGGCCGCTGACATATTCG
CGGGGATCGGGCCGTTGAAA

Product: glutamate--ammonia ligase

Products: NA

Alternate protein names: Glutamate--ammonia ligase II; Glutamine synthetase II; GSII [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTKYKLEYIWLDGYTPVPNLRGKTQIKEFDVFPTLEQLPLWGFDGSSTMQAEGRSSDCVLKPVAIYPDPARTNGALVMCE
VMMPDGVTPHPSNARATILDDEDAWFGFEQEYFFYQNGRPLGFPEQGYPAPQGPYYTGVGYSNVGDVAREIVEEHLDLCL
AAGINHEGINAEVAKGQWEFQIFGKGSKKAADQIWMARYLLQRLTEKYGIDIEYHCKPLGDTDWNGSGMHCNFSTKYMRE
VGGKAYFEALMAQFEKNLMDHIEVYGPDNDKRLTGKHETAPWNKFSYGVADRGASIRVPHSFVKNDYKGYLEDRRPNSQG
CPYQIASQVLKTISEVPTASSASAAA

Sequences:

>Translated_346_residues
MTKYKLEYIWLDGYTPVPNLRGKTQIKEFDVFPTLEQLPLWGFDGSSTMQAEGRSSDCVLKPVAIYPDPARTNGALVMCE
VMMPDGVTPHPSNARATILDDEDAWFGFEQEYFFYQNGRPLGFPEQGYPAPQGPYYTGVGYSNVGDVAREIVEEHLDLCL
AAGINHEGINAEVAKGQWEFQIFGKGSKKAADQIWMARYLLQRLTEKYGIDIEYHCKPLGDTDWNGSGMHCNFSTKYMRE
VGGKAYFEALMAQFEKNLMDHIEVYGPDNDKRLTGKHETAPWNKFSYGVADRGASIRVPHSFVKNDYKGYLEDRRPNSQG
CPYQIASQVLKTISEVPTASSASAAA
>Mature_345_residues
TKYKLEYIWLDGYTPVPNLRGKTQIKEFDVFPTLEQLPLWGFDGSSTMQAEGRSSDCVLKPVAIYPDPARTNGALVMCEV
MMPDGVTPHPSNARATILDDEDAWFGFEQEYFFYQNGRPLGFPEQGYPAPQGPYYTGVGYSNVGDVAREIVEEHLDLCLA
AGINHEGINAEVAKGQWEFQIFGKGSKKAADQIWMARYLLQRLTEKYGIDIEYHCKPLGDTDWNGSGMHCNFSTKYMREV
GGKAYFEALMAQFEKNLMDHIEVYGPDNDKRLTGKHETAPWNKFSYGVADRGASIRVPHSFVKNDYKGYLEDRRPNSQGC
PYQIASQVLKTISEVPTASSASAAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI74271826, Length=343, Percent_Identity=42.8571428571429, Blast_Score=254, Evalue=8e-68,
Organism=Homo sapiens, GI74271837, Length=343, Percent_Identity=42.8571428571429, Blast_Score=254, Evalue=8e-68,
Organism=Homo sapiens, GI19923206, Length=343, Percent_Identity=42.8571428571429, Blast_Score=254, Evalue=8e-68,
Organism=Caenorhabditis elegans, GI115532978, Length=343, Percent_Identity=47.2303206997085, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI115532980, Length=343, Percent_Identity=47.2303206997085, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17554028, Length=346, Percent_Identity=45.9537572254335, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17540008, Length=345, Percent_Identity=45.2173913043478, Blast_Score=268, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17538856, Length=346, Percent_Identity=41.907514450867, Blast_Score=256, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17551038, Length=319, Percent_Identity=40.7523510971787, Blast_Score=216, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6325292, Length=334, Percent_Identity=47.6047904191617, Blast_Score=287, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24641292, Length=338, Percent_Identity=47.9289940828402, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24641290, Length=338, Percent_Identity=47.9289940828402, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI281360453, Length=344, Percent_Identity=45.3488372093023, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI17136208, Length=344, Percent_Identity=45.3488372093023, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24580558, Length=344, Percent_Identity=45.3488372093023, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI45554830, Length=267, Percent_Identity=48.314606741573, Blast_Score=229, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 38814; Mature: 38683

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYKLEYIWLDGYTPVPNLRGKTQIKEFDVFPTLEQLPLWGFDGSSTMQAEGRSSDCVL
CCEEEEEEEEECCCCCCCCCCCCCCHHHCCCCCCHHHCEEECCCCCCEEECCCCCCCEEE
KPVAIYPDPARTNGALVMCEVMMPDGVTPHPSNARATILDDEDAWFGFEQEYFFYQNGRP
EEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCC
LGFPEQGYPAPQGPYYTGVGYSNVGDVAREIVEEHLDLCLAAGINHEGINAEVAKGQWEF
CCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCEEEE
QIFGKGSKKAADQIWMARYLLQRLTEKYGIDIEYHCKPLGDTDWNGSGMHCNFSTKYMRE
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCHHHHHHH
VGGKAYFEALMAQFEKNLMDHIEVYGPDNDKRLTGKHETAPWNKFSYGVADRGASIRVPH
HCCHHHHHHHHHHHHHHHHHHEEEECCCCCCEECCCCCCCCCCCEECCCCCCCCEEECCH
SFVKNDYKGYLEDRRPNSQGCPYQIASQVLKTISEVPTASSASAAA
HHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TKYKLEYIWLDGYTPVPNLRGKTQIKEFDVFPTLEQLPLWGFDGSSTMQAEGRSSDCVL
CEEEEEEEEECCCCCCCCCCCCCCHHHCCCCCCHHHCEEECCCCCCEEECCCCCCCEEE
KPVAIYPDPARTNGALVMCEVMMPDGVTPHPSNARATILDDEDAWFGFEQEYFFYQNGRP
EEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCC
LGFPEQGYPAPQGPYYTGVGYSNVGDVAREIVEEHLDLCLAAGINHEGINAEVAKGQWEF
CCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCEEEE
QIFGKGSKKAADQIWMARYLLQRLTEKYGIDIEYHCKPLGDTDWNGSGMHCNFSTKYMRE
EEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCHHHHHHH
VGGKAYFEALMAQFEKNLMDHIEVYGPDNDKRLTGKHETAPWNKFSYGVADRGASIRVPH
HCCHHHHHHHHHHHHHHHHHHEEEECCCCCCEECCCCCCCCCCCEECCCCCCCCEEECCH
SFVKNDYKGYLEDRRPNSQGCPYQIASQVLKTISEVPTASSASAAA
HHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]