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The map label for this gene is slt [C]

Identifier: 209550191

GI number: 209550191

Start: 2653407

End: 2654339

Strand: Direct

Name: slt [C]

Synonym: Rleg2_2611

Alternate gene names: 209550191

Gene position: 2653407-2654339 (Clockwise)

Preceding gene: 209550190

Following gene: 209550193

Centisome position: 58.47

GC content: 62.17

Gene sequence:

>933_bases
ATGGTAGCGATCGGATTGTCCGGCCTGAAACGCAGTTTTGTCGTTTCGACGATACTCTGTTGCGGCATGATGGCGGGCTG
TGCGAGCGTCGAATACACGTCCCAGGCCGAACTGACCGCTGCCCAGACCGTGGTGCCGATGCCGAAACCCGGTGAAGACG
CCACGCTTGCCGCAATACCGACAGCCGAAGGCACGGCCGGTCAGGCGGTCGGCGGAGCCACCCTTCCCCAGGCATCTCCT
GCCCTGACCGCGACGGCGATGCCGACCGTGACAGCCTCTCAACCTGCCGATCTCACCATGCAGCCGGCGGCCTATGCACA
AATCCCGCTGACACCCGAGATGACGGCGATCCAATCCGTGGTGCCGACGCCGCGTCCGGGAGCCCCAGCACAGCCGACGA
CGCAGCTTGCCTTTGCCGCGACACCGCAGAACGGCGCGCTTGCGGCCCTTGCCGCAGTCGACACCACGCCGCGCGCCAGC
ATGGATTACGGCTTCGACGAATCCGGGCCGATCGATCCGCCGACGGCGCCGCCGATGTTCAGCGACGACGACAAGGACGA
TGCGCCAACGGTCGAAAAGAGCTTCGTCACCAAGCTCATTCAGAAATATTCGAAGCTCTACGAAATTCCCGAGACGCTGC
TCCACCGCATCGTCCATCGCGAGAGCCGCTACAATCCGAAGGCCTACAACAAGCGCGGCTATTTCGGCCTGATGCAGATC
AAGTACAACACTGCCAAATCAATGGGCTATGACGGCGCCCCGGGCGGTCTCTTCGACGCCGAGACCAACATCAAATATGC
CGCGAAATATCTGCGCGGTGCCTGGCTCGTCTCCGACAGCAAGGAAGACGATGCCGTGCGTCTCTATGCGCGCGGCTATT
ATTACGACGCCAAGCGCAAGGGCATGACCGACATCGCCCAGGGCAACTATTAA

Upstream 100 bases:

>100_bases
GCCGGAATGCCACGAATAGGTTAATGGGGTCGTCGGATTTAAGCTTTTTAGTAACTTTTATAACGCTGCCGGGGCGGCAC
GATTTCACGAAAGTGGCGGA

Downstream 100 bases:

>100_bases
GCAATAAACGACTGGAACGACGAAAGCCGTCTATGGCTACGGCTGCGCGCGCTGTTGCGACCCGGCCTGCTGTTGCGGCG
CTCCCGTTTGCGGCAAGGCC

Product: Lytic transglycosylase

Products: 1,6-Anhydrobond [C]

Alternate protein names: Transglycosylase Protein; Transglycosylase; Lytic Murein Transglycosylase; Transglycosylase SLT Domain Protein; Soluble Lytic Transglycosylase; Soluble Lytic Murein Transglycosylase; Transglycosylase Slt Family; Transglycosylase SLT Domain; Transglycosylase SLT Domain-Containing Protein

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MVAIGLSGLKRSFVVSTILCCGMMAGCASVEYTSQAELTAAQTVVPMPKPGEDATLAAIPTAEGTAGQAVGGATLPQASP
ALTATAMPTVTASQPADLTMQPAAYAQIPLTPEMTAIQSVVPTPRPGAPAQPTTQLAFAATPQNGALAALAAVDTTPRAS
MDYGFDESGPIDPPTAPPMFSDDDKDDAPTVEKSFVTKLIQKYSKLYEIPETLLHRIVHRESRYNPKAYNKRGYFGLMQI
KYNTAKSMGYDGAPGGLFDAETNIKYAAKYLRGAWLVSDSKEDDAVRLYARGYYYDAKRKGMTDIAQGNY

Sequences:

>Translated_310_residues
MVAIGLSGLKRSFVVSTILCCGMMAGCASVEYTSQAELTAAQTVVPMPKPGEDATLAAIPTAEGTAGQAVGGATLPQASP
ALTATAMPTVTASQPADLTMQPAAYAQIPLTPEMTAIQSVVPTPRPGAPAQPTTQLAFAATPQNGALAALAAVDTTPRAS
MDYGFDESGPIDPPTAPPMFSDDDKDDAPTVEKSFVTKLIQKYSKLYEIPETLLHRIVHRESRYNPKAYNKRGYFGLMQI
KYNTAKSMGYDGAPGGLFDAETNIKYAAKYLRGAWLVSDSKEDDAVRLYARGYYYDAKRKGMTDIAQGNY
>Mature_310_residues
MVAIGLSGLKRSFVVSTILCCGMMAGCASVEYTSQAELTAAQTVVPMPKPGEDATLAAIPTAEGTAGQAVGGATLPQASP
ALTATAMPTVTASQPADLTMQPAAYAQIPLTPEMTAIQSVVPTPRPGAPAQPTTQLAFAATPQNGALAALAAVDTTPRAS
MDYGFDESGPIDPPTAPPMFSDDDKDDAPTVEKSFVTKLIQKYSKLYEIPETLLHRIVHRESRYNPKAYNKRGYFGLMQI
KYNTAKSMGYDGAPGGLFDAETNIKYAAKYLRGAWLVSDSKEDDAVRLYARGYYYDAKRKGMTDIAQGNY

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 32942; Mature: 32942

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAIGLSGLKRSFVVSTILCCGMMAGCASVEYTSQAELTAAQTVVPMPKPGEDATLAAIP
CEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHEECCCCCCCCCCEEEEEC
TAEGTAGQAVGGATLPQASPALTATAMPTVTASQPADLTMQPAAYAQIPLTPEMTAIQSV
CCCCCCCCCCCCCCCCCCCCCEEEECCCCEECCCCCCCEECCCCEEECCCCCCHHHHHHH
VPTPRPGAPAQPTTQLAFAATPQNGALAALAAVDTTPRASMDYGFDESGPIDPPTAPPMF
CCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
SDDDKDDAPTVEKSFVTKLIQKYSKLYEIPETLLHRIVHRESRYNPKAYNKRGYFGLMQI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
KYNTAKSMGYDGAPGGLFDAETNIKYAAKYLRGAWLVSDSKEDDAVRLYARGYYYDAKRK
EECHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCEEEECCCCCCCEEEEEEECEEEEHHHC
GMTDIAQGNY
CCCCHHCCCC
>Mature Secondary Structure
MVAIGLSGLKRSFVVSTILCCGMMAGCASVEYTSQAELTAAQTVVPMPKPGEDATLAAIP
CEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHEECCCCCCCCCCEEEEEC
TAEGTAGQAVGGATLPQASPALTATAMPTVTASQPADLTMQPAAYAQIPLTPEMTAIQSV
CCCCCCCCCCCCCCCCCCCCCEEEECCCCEECCCCCCCEECCCCEEECCCCCCHHHHHHH
VPTPRPGAPAQPTTQLAFAATPQNGALAALAAVDTTPRASMDYGFDESGPIDPPTAPPMF
CCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
SDDDKDDAPTVEKSFVTKLIQKYSKLYEIPETLLHRIVHRESRYNPKAYNKRGYFGLMQI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
KYNTAKSMGYDGAPGGLFDAETNIKYAAKYLRGAWLVSDSKEDDAVRLYARGYYYDAKRK
EECHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCEEEECCCCCCCEEEEEEECEEEEHHHC
GMTDIAQGNY
CCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA