Click here to switch to the map view.

The map label for this gene is cya1 [H]

Identifier: 209549421

GI number: 209549421

Start: 1874557

End: 1876413

Strand: Reverse

Name: cya1 [H]

Synonym: Rleg2_1827

Alternate gene names: 209549421

Gene position: 1876413-1874557 (Counterclockwise)

Preceding gene: 209549422

Following gene: 209549420

Centisome position: 41.35

GC content: 68.07

Gene sequence:

>1857_bases
ATGAACCATCGCCTGCAGACGGTGATCGCGCTGCTGCTCGCCGGTTTTTGGGGGGCAGCGCTCGGCTATGCCAATCTGAA
GGGCGGAAGCGGCCTGCTCGACCGGATGGAGGCATCGCTTGCCGATATCCGCAGCGTGGTCATCGGGGCGACGACACCGC
CCCCCGTCGTCTCGATCGTTGCGATCGACGACCGCACCGCCGCCGCTCACGGTTATCCCCTTGATCGGGCCACGCTTGCG
CGCCTCGTCGGTGCGATTACCGCCTTGAAGCCGAAGGCGCTGGCGCTCGACATTCTGCTTGTCGATCCGGGGCCGGAGGA
GGGCGATGCGGCGCTGACGGCCGCGCTTGCAGAAGGCCCGAGCGTGATTGCCGCCGCGGCCACTTTTGCCAGGAGCAGGC
AAGAGGTCGCCGATGGGGCGAACGATCCGCTTGCCGCTATCCCCGAGGCAAACCAGCTTCTGTTGCCGCTTGCCCGCTTC
GCCGAAGCCGCCGCCGTCGGTATCGTCAATGTGGCAACCGACCAGACCGGCACGCCGCGCTTCATTCCGCTGATTTCGCG
CGGCACAGACCGATTGGATCCAGCCTTTCCGCTGCGCGCCGCGTCGGTGGCGCTCGGCGTCGATCCGACCATCGAACGCG
ATGCCATCATGCTCGGCGCGCTGCGCATTCCCACAGATATCGGCCAGCGCCTGCCGGTGACCTTCTATGGTGGGCGCGGC
AGCATCGCCACGTCAAGCGCCGCCGACGCGCTTGACGGCAAGCTTTCGGCGGATGCGGTCGCAGGACGGATCGTCGTCAT
CGGCTCGACGGTCACCGGCGGCGGCGACGTCTTCCCGACGCCGTTCGATCCGGTCATGCCCGGCGTCGAGGTGATGTCGA
CGGCGATCACCCATCTCGTCACCGGCGACGGCATGGTGCGCGATCACAGGATGAGGCTGATCGATGCCGCCACGGCCATC
GGATTGCCGCTGGTTTTCGTCTCATTGATCGCCTGGCGGCGGAGTGCGGCGGGCTATATCATCATCGTGCTGACGCTGAT
CGTCTGGGCGCTGCTCAATCTGTCGGCCTTCGCGCATGGCTATTGGCTGAGTGCGGCGCTGCCGATCGCCGCGGCGCTGC
CGCCGGCGCTGATTTTCGGTGCGGCCGAACTCTGGCTCGACCGCGGCCGCGCCCGCCATTTCGCCGAGCAGAGCGCGCTC
CTGCAGCGCATCGAGGCGCCCGGCCTTGGCGAGTGGCTGGCGCGGGATCCGAATTTCCTTGCCAAGCCGGTGCGCCAGAA
CGCTGCCGTCATCTTCATCGATCTCTCGGGTTTCACCGGCCTCAGCGAAAAGCTCGGGCCGGTCAAGGTCAGCCAGGTGC
TGAGCGGCTTCTTCGAACTGATCGACGAGGAGGCGCGCGCTCACGGCGGCGCCATCACCAGTTTCATGGGCGACGGGGCG
ATGATCCTGTTCGGCCTGCCGGAGCCTGCCGATGACGATGCCGCCCGCGCGGCTGCCTGCGCCGTCAGCCTCTGCGAGCG
CACCCGGGCCTGGCTCCAAGCGCATGCGGGCTTCGCCGAGAAGAAGATCGGCTTCAAGGTCGGCGCCCATTGCGGGCCGA
TCGTCGCCTCGCGGCTCGGCACCGGCGACCGGCAGCAGATTACGGCGGCGGGCGACACCATCAATGTCGGCAGCCGGCTG
ATGGAGGTGGCCGCCCTCCATGGCGTCGAACTGGCGCTGAGCGCCGAAATCGTCCGCTCCGCGGGCCCCGACAGCGCGCT
GCTGCAGGCCGGCCGGATGGAGGGTCCGTTGGAAACGGCGCTGCGCGGCAGGGCAAGCCATATCGACACCTGGCTGTGGC
GCAGCCGCACGCTTTGA

Upstream 100 bases:

>100_bases
GAGGGCGTCGACGTCAGCAGCGGGTCGGAACCCCTCGTCGTGCGTCGCTGGCCGGCACCGCGCGCCGCCGCCCTTCTTGC
CCGCCTCGGCCAATAAATCC

Downstream 100 bases:

>100_bases
CAATCGCCGCCGGAGCGGCTAGGAACGGCGCAAATACCCCGCCGGCTGGCTCCGGCCATGGCGCAATTCGCGCCTGACAG
CTCCGAAAGATCGAACTCAT

Product: adenylate/guanylate cyclase with Chase sensor

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1 [H]

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MNHRLQTVIALLLAGFWGAALGYANLKGGSGLLDRMEASLADIRSVVIGATTPPPVVSIVAIDDRTAAAHGYPLDRATLA
RLVGAITALKPKALALDILLVDPGPEEGDAALTAALAEGPSVIAAAATFARSRQEVADGANDPLAAIPEANQLLLPLARF
AEAAAVGIVNVATDQTGTPRFIPLISRGTDRLDPAFPLRAASVALGVDPTIERDAIMLGALRIPTDIGQRLPVTFYGGRG
SIATSSAADALDGKLSADAVAGRIVVIGSTVTGGGDVFPTPFDPVMPGVEVMSTAITHLVTGDGMVRDHRMRLIDAATAI
GLPLVFVSLIAWRRSAAGYIIIVLTLIVWALLNLSAFAHGYWLSAALPIAAALPPALIFGAAELWLDRGRARHFAEQSAL
LQRIEAPGLGEWLARDPNFLAKPVRQNAAVIFIDLSGFTGLSEKLGPVKVSQVLSGFFELIDEEARAHGGAITSFMGDGA
MILFGLPEPADDDAARAAACAVSLCERTRAWLQAHAGFAEKKIGFKVGAHCGPIVASRLGTGDRQQITAAGDTINVGSRL
MEVAALHGVELALSAEIVRSAGPDSALLQAGRMEGPLETALRGRASHIDTWLWRSRTL

Sequences:

>Translated_618_residues
MNHRLQTVIALLLAGFWGAALGYANLKGGSGLLDRMEASLADIRSVVIGATTPPPVVSIVAIDDRTAAAHGYPLDRATLA
RLVGAITALKPKALALDILLVDPGPEEGDAALTAALAEGPSVIAAAATFARSRQEVADGANDPLAAIPEANQLLLPLARF
AEAAAVGIVNVATDQTGTPRFIPLISRGTDRLDPAFPLRAASVALGVDPTIERDAIMLGALRIPTDIGQRLPVTFYGGRG
SIATSSAADALDGKLSADAVAGRIVVIGSTVTGGGDVFPTPFDPVMPGVEVMSTAITHLVTGDGMVRDHRMRLIDAATAI
GLPLVFVSLIAWRRSAAGYIIIVLTLIVWALLNLSAFAHGYWLSAALPIAAALPPALIFGAAELWLDRGRARHFAEQSAL
LQRIEAPGLGEWLARDPNFLAKPVRQNAAVIFIDLSGFTGLSEKLGPVKVSQVLSGFFELIDEEARAHGGAITSFMGDGA
MILFGLPEPADDDAARAAACAVSLCERTRAWLQAHAGFAEKKIGFKVGAHCGPIVASRLGTGDRQQITAAGDTINVGSRL
MEVAALHGVELALSAEIVRSAGPDSALLQAGRMEGPLETALRGRASHIDTWLWRSRTL
>Mature_618_residues
MNHRLQTVIALLLAGFWGAALGYANLKGGSGLLDRMEASLADIRSVVIGATTPPPVVSIVAIDDRTAAAHGYPLDRATLA
RLVGAITALKPKALALDILLVDPGPEEGDAALTAALAEGPSVIAAAATFARSRQEVADGANDPLAAIPEANQLLLPLARF
AEAAAVGIVNVATDQTGTPRFIPLISRGTDRLDPAFPLRAASVALGVDPTIERDAIMLGALRIPTDIGQRLPVTFYGGRG
SIATSSAADALDGKLSADAVAGRIVVIGSTVTGGGDVFPTPFDPVMPGVEVMSTAITHLVTGDGMVRDHRMRLIDAATAI
GLPLVFVSLIAWRRSAAGYIIIVLTLIVWALLNLSAFAHGYWLSAALPIAAALPPALIFGAAELWLDRGRARHFAEQSAL
LQRIEAPGLGEWLARDPNFLAKPVRQNAAVIFIDLSGFTGLSEKLGPVKVSQVLSGFFELIDEEARAHGGAITSFMGDGA
MILFGLPEPADDDAARAAACAVSLCERTRAWLQAHAGFAEKKIGFKVGAHCGPIVASRLGTGDRQQITAAGDTINVGSRL
MEVAALHGVELALSAEIVRSAGPDSALLQAGRMEGPLETALRGRASHIDTWLWRSRTL

Specific function: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 64424; Mature: 64424

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHRLQTVIALLLAGFWGAALGYANLKGGSGLLDRMEASLADIRSVVIGATTPPPVVSIV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCEEEEE
AIDDRTAAAHGYPLDRATLARLVGAITALKPKALALDILLVDPGPEEGDAALTAALAEGP
EECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCC
SVIAAAATFARSRQEVADGANDPLAAIPEANQLLLPLARFAEAAAVGIVNVATDQTGTPR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCC
FIPLISRGTDRLDPAFPLRAASVALGVDPTIERDAIMLGALRIPTDIGQRLPVTFYGGRG
EEEEECCCCCCCCCCCCCHHHHEEECCCCCCCCCCEEEEEEECCHHHCCCCCEEEECCCC
SIATSSAADALDGKLSADAVAGRIVVIGSTVTGGGDVFPTPFDPVMPGVEVMSTAITHLV
CCCCCCHHHHHCCCCCHHHHCCEEEEEECEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TGDGMVRDHRMRLIDAATAIGLPLVFVSLIAWRRSAAGYIIIVLTLIVWALLNLSAFAHG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
YWLSAALPIAAALPPALIFGAAELWLDRGRARHFAEQSALLQRIEAPGLGEWLARDPNFL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHH
AKPVRQNAAVIFIDLSGFTGLSEKLGPVKVSQVLSGFFELIDEEARAHGGAITSFMGDGA
HHHHCCCCEEEEEECCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCE
MILFGLPEPADDDAARAAACAVSLCERTRAWLQAHAGFAEKKIGFKVGAHCGPIVASRLG
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEECCCHHHHHHHHCC
TGDRQQITAAGDTINVGSRLMEVAALHGVELALSAEIVRSAGPDSALLQAGRMEGPLETA
CCCCCEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHH
LRGRASHIDTWLWRSRTL
HCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNHRLQTVIALLLAGFWGAALGYANLKGGSGLLDRMEASLADIRSVVIGATTPPPVVSIV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCEEEEE
AIDDRTAAAHGYPLDRATLARLVGAITALKPKALALDILLVDPGPEEGDAALTAALAEGP
EECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCC
SVIAAAATFARSRQEVADGANDPLAAIPEANQLLLPLARFAEAAAVGIVNVATDQTGTPR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCCC
FIPLISRGTDRLDPAFPLRAASVALGVDPTIERDAIMLGALRIPTDIGQRLPVTFYGGRG
EEEEECCCCCCCCCCCCCHHHHEEECCCCCCCCCCEEEEEEECCHHHCCCCCEEEECCCC
SIATSSAADALDGKLSADAVAGRIVVIGSTVTGGGDVFPTPFDPVMPGVEVMSTAITHLV
CCCCCCHHHHHCCCCCHHHHCCEEEEEECEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TGDGMVRDHRMRLIDAATAIGLPLVFVSLIAWRRSAAGYIIIVLTLIVWALLNLSAFAHG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
YWLSAALPIAAALPPALIFGAAELWLDRGRARHFAEQSALLQRIEAPGLGEWLARDPNFL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHH
AKPVRQNAAVIFIDLSGFTGLSEKLGPVKVSQVLSGFFELIDEEARAHGGAITSFMGDGA
HHHHCCCCEEEEEECCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCE
MILFGLPEPADDDAARAAACAVSLCERTRAWLQAHAGFAEKKIGFKVGAHCGPIVASRLG
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEECCCHHHHHHHHCC
TGDRQQITAAGDTINVGSRLMEVAALHGVELALSAEIVRSAGPDSALLQAGRMEGPLETA
CCCCCEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHH
LRGRASHIDTWLWRSRTL
HCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 1970565 [H]