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The map label for this gene is ureE

Identifier: 209399946

GI number: 209399946

Start: 1337200

End: 1337664

Strand: Direct

Name: ureE

Synonym: ECH74115_1324

Alternate gene names: 209399946

Gene position: 1337200-1337664 (Clockwise)

Preceding gene: 209396808

Following gene: 209400407

Centisome position: 24.0

GC content: 54.84

Gene sequence:

>465_bases
ATGCTTTATTTGACCCGGCGGGTGGAGACCCCGGCTCAGACAACTGCCAGCGTTACCCTCCCTGTTGACATGCGGGTAAA
AAGCCGTATTAAAGTCACCCTTAACGATGGACGTCAGGCTGGACTGTTGCTGCCACGCGGTCTGCTGCTGCGCGATGGTG
ATATTCTCAGTAACGAAAACGGTGATGAATTCATTAAGGTGATCGCCGCTGATGAAGCCGTTTCTGTAGTGCGCTGCGCA
GATCCTTTTATGCTCGCGAAAGCCTGCTGGCATCTCGGCAATCGCCACGTTCCGCTGCAAATAATGCCCGGAGAGCTGCG
CTACCATCACGATCACGTCCTCGATGATATGCTGCGCCAGTTTGGGCTGGATGTTGATTTTGCACATCTTCCGTTTGAGC
CGGAAGCCGGCGCTTACGCCAGCAAGTCGCACGCCCATAATCACGATCAGGAGCACAGCCACTGA

Upstream 100 bases:

>100_bases
ACAAACCTACGAAGTGCGTATCAACGGCGAACTGATAACCAGTGAACCGGCGGACATTCTGCCAATGGCGCAACGTTATT
TCCTGTTTTAAGGAGCACAA

Downstream 100 bases:

>100_bases
ATGCCGACTCCGGAAAAACGTCTGCGGCTGATGCAGCTTGCCAGTAACAGCCTCCCTGTTGGAGGCTACAGCTGGTCCCA
GGGACTGGAGTGGGCAGTGG

Product: urease accessory protein UreE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MLYLTRRVETPAQTTASVTLPVDMRVKSRIKVTLNDGRQAGLLLPRGLLLRDGDILSNENGDEFIKVIAADEAVSVVRCA
DPFMLAKACWHLGNRHVPLQIMPGELRYHHDHVLDDMLRQFGLDVDFAHLPFEPEAGAYASKSHAHNHDQEHSH

Sequences:

>Translated_154_residues
MLYLTRRVETPAQTTASVTLPVDMRVKSRIKVTLNDGRQAGLLLPRGLLLRDGDILSNENGDEFIKVIAADEAVSVVRCA
DPFMLAKACWHLGNRHVPLQIMPGELRYHHDHVLDDMLRQFGLDVDFAHLPFEPEAGAYASKSHAHNHDQEHSH
>Mature_154_residues
MLYLTRRVETPAQTTASVTLPVDMRVKSRIKVTLNDGRQAGLLLPRGLLLRDGDILSNENGDEFIKVIAADEAVSVVRCA
DPFMLAKACWHLGNRHVPLQIMPGELRYHHDHVLDDMLRQFGLDVDFAHLPFEPEAGAYASKSHAHNHDQEHSH

Specific function: Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly

COG id: COG2371

COG function: function code O; Urease accessory protein UreE

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREE_ECO57 (Q8X9U6)

Other databases:

- EMBL:   AE005174
- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   E90794
- PIR:   G85603
- RefSeq:   NP_286681.1
- RefSeq:   NP_287089.1
- RefSeq:   NP_309352.1
- ProteinModelPortal:   Q8X9U6
- SMR:   Q8X9U6
- EnsemblBacteria:   EBESCT00000026368
- EnsemblBacteria:   EBESCT00000027107
- EnsemblBacteria:   EBESCT00000056330
- GeneID:   913913
- GeneID:   958583
- GeneID:   959232
- GenomeReviews:   AE005174_GR
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z1146
- KEGG:   ece:Z1585
- KEGG:   ecs:ECs1325
- GeneTree:   EBGT00050000012845
- HOGENOM:   HBG635302
- OMA:   DARCKSR
- ProtClustDB:   PRK13261
- BioCyc:   ECOL83334:ECS1325-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00822
- InterPro:   IPR012406
- InterPro:   IPR007864
- InterPro:   IPR004029
- Gene3D:   G3DSA:3.30.70.790
- PIRSF:   PIRSF036402

Pfam domain/function: PF05194 UreE_C; PF02814 UreE_N; SSF69737 UreE_C; SSF69287 UreE_N

EC number: NA

Molecular weight: Translated: 17307; Mature: 17307

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYLTRRVETPAQTTASVTLPVDMRVKSRIKVTLNDGRQAGLLLPRGLLLRDGDILSNEN
CEEEECCCCCCCCCCEEEEEEECEEECCEEEEEECCCCCCCEECCCCEEEECCCCCCCCC
GDEFIKVIAADEAVSVVRCADPFMLAKACWHLGNRHVPLQIMPGELRYHHDHVLDDMLRQ
CCCEEEEEECCCHHEEHHHCCHHHHHHHHHHCCCCCCEEEEECCCCEECHHHHHHHHHHH
FGLDVDFAHLPFEPEAGAYASKSHAHNHDQEHSH
HCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLYLTRRVETPAQTTASVTLPVDMRVKSRIKVTLNDGRQAGLLLPRGLLLRDGDILSNEN
CEEEECCCCCCCCCCEEEEEEECEEECCEEEEEECCCCCCCEECCCCEEEECCCCCCCCC
GDEFIKVIAADEAVSVVRCADPFMLAKACWHLGNRHVPLQIMPGELRYHHDHVLDDMLRQ
CCCEEEEEECCCHHEEHHHCCHHHHHHHHHHCCCCCCEEEEECCCCEECHHHHHHHHHHH
FGLDVDFAHLPFEPEAGAYASKSHAHNHDQEHSH
HCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796