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The map label for this gene is apaH [H]

Identifier: 209398997

GI number: 209398997

Start: 55345

End: 56193

Strand: Reverse

Name: apaH [H]

Synonym: ECH74115_0054

Alternate gene names: 209398997

Gene position: 56193-55345 (Counterclockwise)

Preceding gene: 209398324

Following gene: 209399200

Centisome position: 1.01

GC content: 55.95

Gene sequence:

>849_bases
ATGGCGACATACCTTATTGGCGACGTTCATGGTTGTTACGATGAACTGATCGCATTGCTGCATAAAGTAGAATTTACCCC
TGGGAAAGATACCCTCTGGCTGACGGGCGATCTGGTCGCGCGCGGCCCGGGTTCGCTGGATGTTCTGCGCTATGTGAAAT
CCTTAGGCGACAGCGTACGTCTGGTGCTGGGCAATCACGATCTGCATCTGCTGGCAGTATTTGCCGGGATCAGCCGCAAT
AAACCGAAAGATCGCCTGACACCGCTGCTGGAAGCGCCGGATGCCGACGAGCTGCTTAACTGGCTGCGTCGCCAGCCTCT
GCTGCAAATCGACGAAGAGAAAAAGCTGGTGATGGCCCACGCAGGGATCACGCCGCAGTGGGATCTGCAGACCGCCAAAG
AGTGCGCGCGCGATGTAGAAGCGGTGCTGTCGAGTGACTCCTATCCCTTCTTTCTCGACGCTATGTACGGCGATATGCCA
AATAACTGGTCACCGGAATTGCGGGGGCTGGGAAGACTGCGGTTTATCACCAACGCCTTTACCCGTATGCGTTTTTGCTT
CCCGAACGGTCAACTGGATATGTACAGCAAAGAATCGCCGGAAGAGGCCCCTGCCCCACTGAAACCGTGGTTTGCGATTC
CTGGACCTGTCGCTGAAGAATACAGCATCGCCTTTGGTCACTGGGCATCGCTGGAAGGCAAAGGTACGCCGGAAGGTATT
TACGCGCTGGATACCGGCTGCTGCTGGGGTGGGTCATTAACCTGCCTGCGCTGGGAAGATAAACAGTATTTTGTCCAGCC
GTCGAACCGGCATAAGGATTTGGGTGAGGGAGAGGCGGTCGCGTCTTAA

Upstream 100 bases:

>100_bases
GCAGGGTCACTACGAAATGATCGATGAAAATGGCGTCCCTTTCAGCATCGACATTCCCGTATTCCGACTCGCCGTTCCCA
CACTCATTCATTAAAAGAAT

Downstream 100 bases:

>100_bases
ATCCCGTCGAGCATAAAATCTAATGCTCCTTTAATCAACGTTCGGTGCGCGCTGGCATCGCAAAATTTCGTTCCCAGCGC
GTTAACTGGAACAGTTGCAG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRN
KPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGI
YALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGEGEAVAS

Sequences:

>Translated_282_residues
MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRN
KPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGI
YALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGEGEAVAS
>Mature_281_residues
ATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNK
PKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPN
NWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGIY
ALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGEGEAVAS

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=279, Percent_Identity=98.9247311827957, Blast_Score=573, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31497; Mature: 31366

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVR
CCEEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEECCCCHHHHHHHHHHCCCCEE
LVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAH
EEECCCCCEEHHEEHHCCCCCCHHHHCHHHCCCCHHHHHHHHHHCCCEEECCCCEEEEEE
AGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAF
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCCCCCHHHHHCHHHHHHHHHH
TRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGI
HHEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEECCCCCCCCCCE
YALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGEGEAVAS
EEEECCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVR
CEEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEECCCCHHHHHHHHHHCCCCEE
LVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAH
EEECCCCCEEHHEEHHCCCCCCHHHHCHHHCCCCHHHHHHHHHHCCCEEECCCCEEEEEE
AGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAF
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCCCCCHHHHHCHHHHHHHHHH
TRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGI
HHEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEECCCCCCCCCCE
YALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGEGEAVAS
EEEECCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA