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The map label for this gene is ureG

Identifier: 209398478

GI number: 209398478

Start: 1338351

End: 1338968

Strand: Direct

Name: ureG

Synonym: ECH74115_1326

Alternate gene names: 209398478

Gene position: 1338351-1338968 (Clockwise)

Preceding gene: 209400407

Following gene: 209399777

Centisome position: 24.02

GC content: 53.72

Gene sequence:

>618_bases
ATGAACATAATCAAGCAACCGCTGCGTGTCGGCGTCGGCGGTCCGGTCGGCTCAGGTAAAACCGCGCTTCTGGAAGCCCT
CTGCAAATCCATGCGTGACACCTGGCAATTAGCCGTAGTCACCAACGACATCTACACCAGAGAAGATCAACGCATTCTCA
CTGAGGCCGGAGCACTGGAAGCGGAACGCATTGTCGGTGTCGAAACGGGGGGCTGCCCTCATACAGCCATTCGTGAAGAC
GCATCAATGAATCTGGCAGCCGTGGAAGCACTGAGTGAGAAATTTGGTAATCTCGAGCTGATCTTTGTGGAAAGCGGCGG
CGACAACCTGAGTGCGACCTTCAGCCCCGAACTGGCGGACCTTACCATATATGTCATAGATGTGGCAGAAGGAGAAAAGA
TCCCGCGTAAAGGCGGTCCGGGGATCACCAAATCCGACTTCCTCGTGATCAATAAAACTGACCTTGCACCATACGTGGGC
GCCTCCCTCGAGGTAATGGAGCGTGATACTTTACGTATGCGCGGAGAACGCCCATGGGGGTTCACTAACCTGAAAAGTGG
TGAAGGTCTGCAAAACATCATCGCCTTTATCGAAGAGCAGGGCATGCTGGGTAAGTAA

Upstream 100 bases:

>100_bases
CGGATCACGCAATTGGTTCAGCAACGCCACTTGCATCTATCGCTTCCGCGCGACATGAAACCCAGTATTCCCGATTATTC
CGTTCTTAGGAGAAAATAAA

Downstream 100 bases:

>100_bases
TCACAACATCCTCTGTATCAGGGCCGGCAGGCGGCCCCTTGTTTTTATCAGAAGGAATAACGGAAGTTGGCGTTCACCGC
GTTATCCACGTTGTACTTAC

Product: urease accessory protein UreG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MNIIKQPLRVGVGGPVGSGKTALLEALCKSMRDTWQLAVVTNDIYTREDQRILTEAGALEAERIVGVETGGCPHTAIRED
ASMNLAAVEALSEKFGNLELIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITKSDFLVINKTDLAPYVG
ASLEVMERDTLRMRGERPWGFTNLKSGEGLQNIIAFIEEQGMLGK

Sequences:

>Translated_205_residues
MNIIKQPLRVGVGGPVGSGKTALLEALCKSMRDTWQLAVVTNDIYTREDQRILTEAGALEAERIVGVETGGCPHTAIRED
ASMNLAAVEALSEKFGNLELIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITKSDFLVINKTDLAPYVG
ASLEVMERDTLRMRGERPWGFTNLKSGEGLQNIIAFIEEQGMLGK
>Mature_205_residues
MNIIKQPLRVGVGGPVGSGKTALLEALCKSMRDTWQLAVVTNDIYTREDQRILTEAGALEAERIVGVETGGCPHTAIRED
ASMNLAAVEALSEKFGNLELIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITKSDFLVINKTDLAPYVG
ASLEVMERDTLRMRGERPWGFTNLKSGEGLQNIIAFIEEQGMLGK

Specific function: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by ureG

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ureG family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UREG_ECO57 (Q8X9U4)

Other databases:

- EMBL:   AE005174
- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A85604
- PIR:   G90794
- RefSeq:   NP_286683.1
- RefSeq:   NP_287091.1
- RefSeq:   NP_309354.1
- ProteinModelPortal:   Q8X9U4
- SMR:   Q8X9U4
- EnsemblBacteria:   EBESCT00000026237
- EnsemblBacteria:   EBESCT00000026754
- EnsemblBacteria:   EBESCT00000056607
- GeneID:   912768
- GeneID:   958601
- GeneID:   959235
- GenomeReviews:   AE005174_GR
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z1148
- KEGG:   ece:Z1587
- KEGG:   ecs:ECs1327
- GeneTree:   EBGT00050000012888
- HOGENOM:   HBG364734
- OMA:   LCKAMRE
- ProtClustDB:   CLSK879809
- BioCyc:   ECOL83334:ECS1327-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01389
- InterPro:   IPR003495
- InterPro:   IPR012202
- InterPro:   IPR004400
- PIRSF:   PIRSF005624
- TIGRFAMs:   TIGR00101

Pfam domain/function: PF02492 cobW

EC number: NA

Molecular weight: Translated: 22125; Mature: 22125

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIKQPLRVGVGGPVGSGKTALLEALCKSMRDTWQLAVVTNDIYTREDQRILTEAGALE
CCCHHCHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEECCHHCCCHHHHHHHHCCCC
AERIVGVETGGCPHTAIREDASMNLAAVEALSEKFGNLELIFVESGGDNLSATFSPELAD
HHHEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCEEEECCCCCE
LTIYVIDVAEGEKIPRKGGPGITKSDFLVINKTDLAPYVGASLEVMERDTLRMRGERPWG
EEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEHHHHHHHHCCCCCCC
FTNLKSGEGLQNIIAFIEEQGMLGK
CCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNIIKQPLRVGVGGPVGSGKTALLEALCKSMRDTWQLAVVTNDIYTREDQRILTEAGALE
CCCHHCHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEEEEEECCHHCCCHHHHHHHHCCCC
AERIVGVETGGCPHTAIREDASMNLAAVEALSEKFGNLELIFVESGGDNLSATFSPELAD
HHHEEEEECCCCCCHHHHCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCEEEECCCCCE
LTIYVIDVAEGEKIPRKGGPGITKSDFLVINKTDLAPYVGASLEVMERDTLRMRGERPWG
EEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEHHHHHHHHCCCCCCC
FTNLKSGEGLQNIIAFIEEQGMLGK
CCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796