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The map label for this gene is invA [H]

Identifier: 209398095

GI number: 209398095

Start: 3833628

End: 3835688

Strand: Reverse

Name: invA [H]

Synonym: ECH74115_4147

Alternate gene names: 209398095

Gene position: 3835688-3833628 (Counterclockwise)

Preceding gene: 209400791

Following gene: 209396176

Centisome position: 68.84

GC content: 37.36

Gene sequence:

>2061_bases
ATGTTTAACAAAGTTTTGGTAGGGTTAAGGAGTCATCCAGAATTAATAATTCTTGGATTAATGGTGATGATTATCGCCAT
GCTCATAATTCCATTGCCCACCTATTTAATCGACTTTTTGATTGGGCTTAACTTAACATTGGCAATACTTGTATTTTTAG
GATCATTCTATGTTGATAGGATCTTAAGCTTTTCTTCATTTCCATCAATCCTCCTTATCACAACGTTATTTCGTTTGGCG
CTGGCGATCAGTACCAGTCGACTTATACTTCTTGAGGCGGATGCTGGAGAAATTATAACGAGTTTTGGTGAGTTCGTTAT
TGGAGATAGCCTGGTAGTTGGTTTTGTTATTTTCTCCATTGTTACTATTGTTCAGTTTATCGTGATTACTAAAGGTTCGG
AACGTGTGGCTGAAGTTGCTGCCCGCTTTTCGCTTGACGGTATGCCAGGTAAACAAATGAGCATTGACGCCGATCTACGC
GCCGGGATCATTGATGCAGATTTAGCAAAAGAACGTCGTAGTGTATTAGAACGAGAGAGCCAGTTGTATGGTTCCTTTGA
TGGTGCGATGAAATTTATCAAAGGTGATGCTATTGCAAACATTATTATTATCTTTGTTAATATTATCGGTGGGCTATCAG
TAGGAGTAGGCCAAAATGGAATGGATTTCTCAACAGCGTTGACTGTCTACACAATTCTTACTGTCGGTGATGGTCTTGTT
TCTCAAATTCCAGCTTTATTAATTGCTATTAGCGCAGGATTTATCGTTACGCGCGTAAATGGCGATAGTGATAATATGGG
GCAAAATATAATGTCCCAGTTATTAAGTAATTCTTTTGTCATTGTTGTGACATGTGTCCTCGCGCTAAGTATTGGGTTGC
TTCCAGGTTTTCCCCTTCTAGTGTTTTTATGTTTGGCAGTAATCTTAGGAATTTACTTTTACTTTAAATTCAAAAAGAAA
GGGACTGAAGAAACGGTTGTTGAGGGAGATATTACCGTTGGGTTGGAACCCTATAATCAAGATGATGATATCTCATTAGG
TATCATTAATAAACTTGATCAGGTTATTACCGAAACGGTACCCTTGGTCTTGATTATGAATAGTGTACAGGCTAAAAAAT
ACACTGAAATCAATCTTGCTGATAGGATTCGTAGTCAGTTTTTTATTGAGTATGGTATCCGCATTCCCGGTATTGTCATT
CGTGAGGGGGAAGGTCTTAATGATGAAGATGTCATATTAATGCTAAATGAAGTCAGAGCTTCACAATTTAAAATTTATCA
TGATCTTGTCTTGTTGGTTGAATATTCAGATGAAGTGGTTTCGACTTTGATCAAGAAACCTGTCATTGTAAATAGTAATG
GTGAACAATATTATTGGGTTACGAAAAGTGATGCTCAAAAATTAACAAAAATTGGCTGTTATACTCGCACGGCCATGGAT
GAAATGTATAATCATTTATCTGTCTGTCTGGCTCATAATATTAATGAGTACTTTGGTATACAAGAAACAAAATATATTCT
TGATCAATTAGAGATGAAGTATTCTGATCTATTAAAAGAAATATTAAGATATATAACCGTGCAGCGCATTTCAGAGGTAA
TTCAGCGTCTGATCCAGGAGCGAATTTCAGTGCGCAATATGCGGTTAGTTATGGAGGCCTTAGCATTATGGAGCCCACGA
GAGAAAGATATAATCACACTCGTCGAGCATGTACGAGGTGCATTAGGTCGCTACATTTGCCATAAGTTTTCATATTCTGG
AGAAATTAAAGCAATTGTGATTTCGCCTGAAATAGAGGACAGAATCAGAGATGGTGTCAGGCCTACCGCTGGCGGTACTT
TTCTTAATCTCGATGCATCCGAAGCTGAGATGATTCTGGATAATTTTAAACTGGCACTTTCTGGAATCAATATTCCTATT
AAAGACATTATTTTACTGGGATCTGTGGATATTCGTCGTTTTATCAAAAAACTTATTGAATCTAGTTATCGAGACCTCGA
AGTACTTTCGTACGGGGAACTAACGGAAAATGTTCCCGTTAATATTCTGAAAACTATTTAG

Upstream 100 bases:

>100_bases
TGTAAACAGGCAATAAAAGTAACATTTGCAGCAGAGCTCTTTGATACACAAAACTGTAACAAAAAACAAAATAAAAAACC
ATGGAAGAAGGTGATGTTCA

Downstream 100 bases:

>100_bases
GATAATGTCTTGCGATATGGAGCATGCTGGTATGAAAAAATTAAAATTATTAAATAAATACAGCTACTTACATAGCATAA
ACGGCTCTCTGATTGAAGCA

Product: type III secretion protein, HrcV family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MFNKVLVGLRSHPELIILGLMVMIIAMLIIPLPTYLIDFLIGLNLTLAILVFLGSFYVDRILSFSSFPSILLITTLFRLA
LAISTSRLILLEADAGEIITSFGEFVIGDSLVVGFVIFSIVTIVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLR
AGIIDADLAKERRSVLERESQLYGSFDGAMKFIKGDAIANIIIIFVNIIGGLSVGVGQNGMDFSTALTVYTILTVGDGLV
SQIPALLIAISAGFIVTRVNGDSDNMGQNIMSQLLSNSFVIVVTCVLALSIGLLPGFPLLVFLCLAVILGIYFYFKFKKK
GTEETVVEGDITVGLEPYNQDDDISLGIINKLDQVITETVPLVLIMNSVQAKKYTEINLADRIRSQFFIEYGIRIPGIVI
REGEGLNDEDVILMLNEVRASQFKIYHDLVLLVEYSDEVVSTLIKKPVIVNSNGEQYYWVTKSDAQKLTKIGCYTRTAMD
EMYNHLSVCLAHNINEYFGIQETKYILDQLEMKYSDLLKEILRYITVQRISEVIQRLIQERISVRNMRLVMEALALWSPR
EKDIITLVEHVRGALGRYICHKFSYSGEIKAIVISPEIEDRIRDGVRPTAGGTFLNLDASEAEMILDNFKLALSGINIPI
KDIILLGSVDIRRFIKKLIESSYRDLEVLSYGELTENVPVNILKTI

Sequences:

>Translated_686_residues
MFNKVLVGLRSHPELIILGLMVMIIAMLIIPLPTYLIDFLIGLNLTLAILVFLGSFYVDRILSFSSFPSILLITTLFRLA
LAISTSRLILLEADAGEIITSFGEFVIGDSLVVGFVIFSIVTIVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLR
AGIIDADLAKERRSVLERESQLYGSFDGAMKFIKGDAIANIIIIFVNIIGGLSVGVGQNGMDFSTALTVYTILTVGDGLV
SQIPALLIAISAGFIVTRVNGDSDNMGQNIMSQLLSNSFVIVVTCVLALSIGLLPGFPLLVFLCLAVILGIYFYFKFKKK
GTEETVVEGDITVGLEPYNQDDDISLGIINKLDQVITETVPLVLIMNSVQAKKYTEINLADRIRSQFFIEYGIRIPGIVI
REGEGLNDEDVILMLNEVRASQFKIYHDLVLLVEYSDEVVSTLIKKPVIVNSNGEQYYWVTKSDAQKLTKIGCYTRTAMD
EMYNHLSVCLAHNINEYFGIQETKYILDQLEMKYSDLLKEILRYITVQRISEVIQRLIQERISVRNMRLVMEALALWSPR
EKDIITLVEHVRGALGRYICHKFSYSGEIKAIVISPEIEDRIRDGVRPTAGGTFLNLDASEAEMILDNFKLALSGINIPI
KDIILLGSVDIRRFIKKLIESSYRDLEVLSYGELTENVPVNILKTI
>Mature_686_residues
MFNKVLVGLRSHPELIILGLMVMIIAMLIIPLPTYLIDFLIGLNLTLAILVFLGSFYVDRILSFSSFPSILLITTLFRLA
LAISTSRLILLEADAGEIITSFGEFVIGDSLVVGFVIFSIVTIVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLR
AGIIDADLAKERRSVLERESQLYGSFDGAMKFIKGDAIANIIIIFVNIIGGLSVGVGQNGMDFSTALTVYTILTVGDGLV
SQIPALLIAISAGFIVTRVNGDSDNMGQNIMSQLLSNSFVIVVTCVLALSIGLLPGFPLLVFLCLAVILGIYFYFKFKKK
GTEETVVEGDITVGLEPYNQDDDISLGIINKLDQVITETVPLVLIMNSVQAKKYTEINLADRIRSQFFIEYGIRIPGIVI
REGEGLNDEDVILMLNEVRASQFKIYHDLVLLVEYSDEVVSTLIKKPVIVNSNGEQYYWVTKSDAQKLTKIGCYTRTAMD
EMYNHLSVCLAHNINEYFGIQETKYILDQLEMKYSDLLKEILRYITVQRISEVIQRLIQERISVRNMRLVMEALALWSPR
EKDIITLVEHVRGALGRYICHKFSYSGEIKAIVISPEIEDRIRDGVRPTAGGTFLNLDASEAEMILDNFKLALSGINIPI
KDIILLGSVDIRRFIKKLIESSYRDLEVLSYGELTENVPVNILKTI

Specific function: Involved in the invasion of the cells of the intestinal epithelium. Could be involved in the translocation of the invE protein [H]

COG id: COG4789

COG function: function code U; Type III secretory pathway, component EscV

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=679, Percent_Identity=34.9042709867452, Blast_Score=352, Evalue=4e-98,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001712
- InterPro:   IPR006302 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 76382; Mature: 76382

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNKVLVGLRSHPELIILGLMVMIIAMLIIPLPTYLIDFLIGLNLTLAILVFLGSFYVDR
CCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSFSSFPSILLITTLFRLALAISTSRLILLEADAGEIITSFGEFVIGDSLVVGFVIFSI
HHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHH
VTIVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLRAGIIDADLAKERRSVLERES
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEECCHHHCCCCCHHHHHHHHHHHHHHH
QLYGSFDGAMKFIKGDAIANIIIIFVNIIGGLSVGVGQNGMDFSTALTVYTILTVGDGLV
HHHCCHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCHHH
SQIPALLIAISAGFIVTRVNGDSDNMGQNIMSQLLSNSFVIVVTCVLALSIGLLPGFPLL
HHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHH
VFLCLAVILGIYFYFKFKKKGTEETVVEGDITVGLEPYNQDDDISLGIINKLDQVITETV
HHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
PLVLIMNSVQAKKYTEINLADRIRSQFFIEYGIRIPGIVIREGEGLNDEDVILMLNEVRA
HHHHHHHHHHHHHEEECCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEEHHHH
SQFKIYHDLVLLVEYSDEVVSTLIKKPVIVNSNGEQYYWVTKSDAQKLTKIGCYTRTAMD
HHHHHHHHEEEEEECCHHHHHHHHHCCEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHH
EMYNHLSVCLAHNINEYFGIQETKYILDQLEMKYSDLLKEILRYITVQRISEVIQRLIQE
HHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RISVRNMRLVMEALALWSPREKDIITLVEHVRGALGRYICHKFSYSGEIKAIVISPEIED
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHH
RIRDGVRPTAGGTFLNLDASEAEMILDNFKLALSGINIPIKDIILLGSVDIRRFIKKLIE
HHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHEECCHHHHHHHHHHHH
SSYRDLEVLSYGELTENVPVNILKTI
CCCCCEEHEECCCCCCCCCCHHHCCC
>Mature Secondary Structure
MFNKVLVGLRSHPELIILGLMVMIIAMLIIPLPTYLIDFLIGLNLTLAILVFLGSFYVDR
CCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSFSSFPSILLITTLFRLALAISTSRLILLEADAGEIITSFGEFVIGDSLVVGFVIFSI
HHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHH
VTIVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLRAGIIDADLAKERRSVLERES
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEEECCHHHCCCCCHHHHHHHHHHHHHHH
QLYGSFDGAMKFIKGDAIANIIIIFVNIIGGLSVGVGQNGMDFSTALTVYTILTVGDGLV
HHHCCHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCHHH
SQIPALLIAISAGFIVTRVNGDSDNMGQNIMSQLLSNSFVIVVTCVLALSIGLLPGFPLL
HHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHH
VFLCLAVILGIYFYFKFKKKGTEETVVEGDITVGLEPYNQDDDISLGIINKLDQVITETV
HHHHHHHHHHHHHHHHHCCCCCCCCEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
PLVLIMNSVQAKKYTEINLADRIRSQFFIEYGIRIPGIVIREGEGLNDEDVILMLNEVRA
HHHHHHHHHHHHHEEECCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEEHHHH
SQFKIYHDLVLLVEYSDEVVSTLIKKPVIVNSNGEQYYWVTKSDAQKLTKIGCYTRTAMD
HHHHHHHHEEEEEECCHHHHHHHHHCCEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHH
EMYNHLSVCLAHNINEYFGIQETKYILDQLEMKYSDLLKEILRYITVQRISEVIQRLIQE
HHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RISVRNMRLVMEALALWSPREKDIITLVEHVRGALGRYICHKFSYSGEIKAIVISPEIED
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHH
RIRDGVRPTAGGTFLNLDASEAEMILDNFKLALSGINIPIKDIILLGSVDIRRFIKKLIE
HHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHEECCHHHHHHHHHHHH
SSYRDLEVLSYGELTENVPVNILKTI
CCCCCEEHEECCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]