BacMap

Definition	Escherichia coli O157:H7 str. EC4115, complete genome.
Accession	NC_011353
Length	5,572,075

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The map label for this gene is ygcW [H]

Identifier: 209397522

GI number: 209397522

Start: 3724002

End: 3724787

Strand: Reverse

Name: ygcW [H]

Synonym: ECH74115_4030

Alternate gene names: 209397522

Gene position: 3724787-3724002 (Counterclockwise)

Preceding gene: 209398503

Following gene: 209399257

Centisome position: 66.85

GC content: 46.06

Gene sequence:

>786_bases
ATGTCAATCGAATCTCTCAATGCGTTCTCAATGGATTTTTTCTCCCTGAAAGGTAAAACCGCAATTGTTACCGGCGGGAA
TAGCGGTTTAGGCCAGGCATTTGCCATGGCGTTGGCCAAAGCAGGCGCAAATGTCTTTATTCCAAGTTTTGTCAAAGATA
ACGGCGAAACAAAGGAAATGATTGAAAATCAGGGTGTTGAGGTGGACTTCATGCAGGTGGATATCACCGCAGAAGGCGCG
CCGCAGAAGATTATCGCTGCCTGCTGTGAGCGTTTCGGTACAGTTGATATTCTGGTTAACAATGCCGGTATTTGTAAGCT
GAATAAGGTGCTGGACTTCGGTCGTGCCGACTGGGACCCGATGATTGATGTGAACCTGACCGCCGCATTCGAGTTAAGCT
ACGAAGCGGCAAAAATTATGATCCCGCAGAAAAGCGGTAAAATCATTAATATCTGTTCATTGTTCTCTTACTTAGGTGGA
CAATGGTCACCTGCATATTCTGCTACTAAACATGCTCTTGCCGGATTCACCAAAGCTTATTGTGATGAACTAGGTCAATA
TAATATTCAGGTAAATGGTATCGCCCCTGGCTATTATGCAACAGACATTACGCTGGCGACACGCAGTAATCCAGAAACCA
ATCAGCGCGTTCTTGATCATATTCCGGCAAACCGTTGGGGCGATACTCAGGATTTAATGGGCGCAGCCGTGTTTCTCGCA
AGTCAGGCATCGAATTATGTCAACGGGCATTTATTAGTGGTCGATGGCGGTTATTTAGTGCGCTAA

Upstream 100 bases:

>100_bases
AAATTATCTCCAGTTACCAGAGATAATGAGAAAGGTAACTTCCCTCTCGCGGGGGAAGTTACCTTTCTTTTTTTTTGCCT
TACGGAAATTGGAGCTAACT

Downstream 100 bases:

>100_bases
CCCATAACGGTGGTTTCTGTTTTCTCTTATTAATGATTATTCCATTTTTATTATCAGGAAGGAATTACTATGTCTTTATC
TCGCGCAGCGATTGTCGACC

Product: oxidoreductase, short chain dehydrogenase/reductase family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIENQGVEVDFMQVDITAEGA
PQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGG
QWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLA
SQASNYVNGHLLVVDGGYLVR

Sequences:

>Translated_261_residues
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIENQGVEVDFMQVDITAEGA
PQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGG
QWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLA
SQASNYVNGHLLVVDGGYLVR
>Mature_260_residues
SIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIENQGVEVDFMQVDITAEGAP
QKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQ
WSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLAS
QASNYVNGHLLVVDGGYLVR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=30.1255230125523, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=27.0161290322581, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=30.4, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=30.3030303030303, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=29.2181069958848, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=29.8387096774194, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI4758504, Length=256, Percent_Identity=30.859375, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI31542939, Length=220, Percent_Identity=29.5454545454545, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7706318, Length=196, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4504505, Length=189, Percent_Identity=32.2751322751323, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI20149619, Length=200, Percent_Identity=30, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=26.4, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=30.4597701149425, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI59889578, Length=229, Percent_Identity=29.6943231441048, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=25.4032258064516, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=29.2307692307692, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=25.5905511811024, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI83715985, Length=257, Percent_Identity=29.5719844357977, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4503301, Length=248, Percent_Identity=26.6129032258064, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503817, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7657478, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082160, Length=261, Percent_Identity=98.4674329501916, Blast_Score=532, Evalue=1e-153,
Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=44, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=40.4, Blast_Score=192, Evalue=1e-50,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=33.8709677419355, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=34.5381526104418, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=34.8, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=28.9156626506024, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=28.515625, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=26.5060240963855, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=29.9595141700405, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=28.2442748091603, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786701, Length=190, Percent_Identity=25.7894736842105, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=32.6530612244898, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=31.0756972111554, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=33.6032388663968, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=31.7460317460317, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17559104, Length=256, Percent_Identity=33.203125, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=30.6451612903226, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=28.8617886178862, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=30.2681992337165, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=30.1115241635688, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=30.4182509505703, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=31.0344827586207, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=31.1787072243346, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=31.0861423220974, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=25.9109311740891, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17563726, Length=269, Percent_Identity=30.8550185873606, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=29.1187739463602, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=29.0697674418605, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=28.735632183908, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=29.6153846153846, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=257, Percent_Identity=26.8482490272374, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17568967, Length=190, Percent_Identity=31.0526315789474, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=259, Percent_Identity=27.7992277992278, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=30.1526717557252, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=27.9245283018868, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=31.0077519379845, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=25.5725190839695, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=25.2, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=24.8, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=201, Percent_Identity=28.8557213930348, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=28.2722513089005, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=191, Percent_Identity=28.7958115183246, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=201, Percent_Identity=27.8606965174129, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=250, Percent_Identity=27.2, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=25.296442687747, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71997099, Length=238, Percent_Identity=28.1512605042017, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17557668, Length=204, Percent_Identity=29.9019607843137, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=198, Percent_Identity=23.7373737373737, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=198, Percent_Identity=23.7373737373737, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=32.8205128205128, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=26.7716535433071, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=27.6422764227642, Blast_Score=75, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320089, Length=208, Percent_Identity=27.4038461538462, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=32.7935222672065, Blast_Score=124, Evalue=6e-29,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=31.0483870967742, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=32.5396825396825, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=31.0756972111554, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=30.2788844621514, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=28.9156626506024, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=29.8039215686275, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=30.5263157894737, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24649181, Length=202, Percent_Identity=27.7227722772277, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21358495, Length=204, Percent_Identity=27.4509803921569, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=28.6458333333333, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=28.6458333333333, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640442, Length=224, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21355631, Length=185, Percent_Identity=28.1081081081081, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24644337, Length=176, Percent_Identity=27.8409090909091, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007236, Length=195, Percent_Identity=27.6923076923077, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28103; Mature: 27972

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEM
CCCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCEEECHHHCCCCCHHHH
IENQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDP
HHHCCCEEEEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCEEHHHHHHCCCCCCCC
MIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAY
EEEEEEEEEEEEEECEEEEEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
CDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLA
HHHHCCEEEEEEEECCCEEEEEEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SQASNYVNGHLLVVDGGYLVR
HHCCCCCCCEEEEEECCEEEC
>Mature Secondary Structure 
SIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEM
CCCCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCEEECHHHCCCCCHHHH
IENQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDP
HHHCCCEEEEEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCEEHHHHHHCCCCCCCC
MIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAY
EEEEEEEEEEEEEECEEEEEEECCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
CDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLA
HHHHCCEEEEEEEECCCEEEEEEEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHH
SQASNYVNGHLLVVDGGYLVR
HHCCCCCCCEEEEEECCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9205837 [H]